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daunorubicin e assays  (Enamine Ltd)


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    Enamine Ltd daunorubicin e assays
    Concentration-effect curves of compound 21 (●) against ABCB1 (A and D), ABCC1 (B and E), and ABCG2 (C and F) as determined in calcein AM (A and B), pheophorbide A (C), Hoechst 33342 (D and F), and <t>daunorubicin</t> (E) assays using ABCB1-overexpressing A2780/ADR cells (A and D), ABCC1-overexpressing H69AR cells (B and E), or ABCG2-overexpressing MDCK II BCRP cells (C and F). Data were normalized by defining the effect of 10 μM cyclosporine A (▲; A, B, D, and E) and compound 34 (▲; C and F) as a positive control (100%) and buffer medium as a negative control (0%). Shown is the mean ± SEM of at least three independent experiments.
    Daunorubicin E Assays, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/daunorubicin e assays/product/Enamine Ltd
    Average 90 stars, based on 1 article reviews
    daunorubicin e assays - by Bioz Stars, 2026-04
    90/100 stars

    Images

    1) Product Images from "C@PA: Computer-Aided Pattern Analysis to Predict Multitarget ABC Transporter Inhibitors"

    Article Title: C@PA: Computer-Aided Pattern Analysis to Predict Multitarget ABC Transporter Inhibitors

    Journal: Journal of Medicinal Chemistry

    doi: 10.1021/acs.jmedchem.0c02199

    Concentration-effect curves of compound 21 (●) against ABCB1 (A and D), ABCC1 (B and E), and ABCG2 (C and F) as determined in calcein AM (A and B), pheophorbide A (C), Hoechst 33342 (D and F), and daunorubicin (E) assays using ABCB1-overexpressing A2780/ADR cells (A and D), ABCC1-overexpressing H69AR cells (B and E), or ABCG2-overexpressing MDCK II BCRP cells (C and F). Data were normalized by defining the effect of 10 μM cyclosporine A (▲; A, B, D, and E) and compound 34 (▲; C and F) as a positive control (100%) and buffer medium as a negative control (0%). Shown is the mean ± SEM of at least three independent experiments.
    Figure Legend Snippet: Concentration-effect curves of compound 21 (●) against ABCB1 (A and D), ABCC1 (B and E), and ABCG2 (C and F) as determined in calcein AM (A and B), pheophorbide A (C), Hoechst 33342 (D and F), and daunorubicin (E) assays using ABCB1-overexpressing A2780/ADR cells (A and D), ABCC1-overexpressing H69AR cells (B and E), or ABCG2-overexpressing MDCK II BCRP cells (C and F). Data were normalized by defining the effect of 10 μM cyclosporine A (▲; A, B, D, and E) and compound 34 (▲; C and F) as a positive control (100%) and buffer medium as a negative control (0%). Shown is the mean ± SEM of at least three independent experiments.

    Techniques Used: Concentration Assay, Positive Control, Negative Control



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    daunorubicin e assays  (Enamine Ltd)
    90
    Enamine Ltd daunorubicin e assays
    Concentration-effect curves of compound 21 (●) against ABCB1 (A and D), ABCC1 (B and E), and ABCG2 (C and F) as determined in calcein AM (A and B), pheophorbide A (C), Hoechst 33342 (D and F), and <t>daunorubicin</t> (E) assays using ABCB1-overexpressing A2780/ADR cells (A and D), ABCC1-overexpressing H69AR cells (B and E), or ABCG2-overexpressing MDCK II BCRP cells (C and F). Data were normalized by defining the effect of 10 μM cyclosporine A (▲; A, B, D, and E) and compound 34 (▲; C and F) as a positive control (100%) and buffer medium as a negative control (0%). Shown is the mean ± SEM of at least three independent experiments.
    Daunorubicin E Assays, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/daunorubicin e assays/product/Enamine Ltd
    Average 90 stars, based on 1 article reviews
    daunorubicin e assays - by Bioz Stars, 2026-04
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Concentration-effect curves of compound 21 (●) against ABCB1 (A and D), ABCC1 (B and E), and ABCG2 (C and F) as determined in calcein AM (A and B), pheophorbide A (C), Hoechst 33342 (D and F), and daunorubicin (E) assays using ABCB1-overexpressing A2780/ADR cells (A and D), ABCC1-overexpressing H69AR cells (B and E), or ABCG2-overexpressing MDCK II BCRP cells (C and F). Data were normalized by defining the effect of 10 μM cyclosporine A (▲; A, B, D, and E) and compound 34 (▲; C and F) as a positive control (100%) and buffer medium as a negative control (0%). Shown is the mean ± SEM of at least three independent experiments.

    Journal: Journal of Medicinal Chemistry

    Article Title: C@PA: Computer-Aided Pattern Analysis to Predict Multitarget ABC Transporter Inhibitors

    doi: 10.1021/acs.jmedchem.0c02199

    Figure Lengend Snippet: Concentration-effect curves of compound 21 (●) against ABCB1 (A and D), ABCC1 (B and E), and ABCG2 (C and F) as determined in calcein AM (A and B), pheophorbide A (C), Hoechst 33342 (D and F), and daunorubicin (E) assays using ABCB1-overexpressing A2780/ADR cells (A and D), ABCC1-overexpressing H69AR cells (B and E), or ABCG2-overexpressing MDCK II BCRP cells (C and F). Data were normalized by defining the effect of 10 μM cyclosporine A (▲; A, B, D, and E) and compound 34 (▲; C and F) as a positive control (100%) and buffer medium as a negative control (0%). Shown is the mean ± SEM of at least three independent experiments.

    Article Snippet: The complete dataset of categorized and classified 1049 compounds (Supplementary Tables 1–3); statistical analysis of substructure search (Supplementary Table 4); and molecular formula strings of “Screen 5” compounds before manual selection (Supplementary Table 5) ( ZIP ) Molecular formula strings and the biological data of compounds 11 – 33 (Supplementary Table 6) ( CSV ) Concentration-effect curves of compound 15 against ABCB1 (A and D), ABCC1 (B and E), and ABCG2 (C and F) as determined in calcein AM (A and B), pheophorbide A (C), Hoechst 33342 (D and F), and daunorubicin (E) assays (Supplementary Figure 1 A–F); concentration-effect curves of compound 18 against ABCB1 (A and D), ABCC1 (B and E), and ABCG2 (C and F) as determined in calcein AM (A and B), pheophorbide A (C), Hoechst 33342 (D and F), and daunorubicin (E) assays (Supplementary Figure 2 A–F); concentration-effect curves of compound 22 against ABCB1 (A and D), ABCC1 (B and E), and ABCG2 (C and F) as determined in calcein AM (A and B), pheophorbide A (C), Hoechst 33342 (D and F), and daunorubicin (E) assays (Supplementary Figure 3 A–F); concentration-effect curves of compound 26 against ABCB1 (A and D), ABCC1 (B and E), and ABCG2 (C and F) as determined in calcein AM (A and B), pheophorbide A (C), Hoechst 33342 (D and F), and daunorubicin (E) assays (Supplementary Figure 4 A–F); and LC-MS data of compounds 11 – 33 as provided by ENAMINE ( PDF )

    Techniques: Concentration Assay, Positive Control, Negative Control