combretastatin a 4  (Millipore)


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  • 94
    Name:
    Combretastatin A4
    Description:

    Catalog Number:
    c7744
    Price:
    None
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    Structured Review

    Millipore combretastatin a 4
    Combretastatin A4

    https://www.bioz.com/result/combretastatin a 4/product/Millipore
    Average 94 stars, based on 2 article reviews
    Price from $9.99 to $1999.99
    combretastatin a 4 - by Bioz Stars, 2020-10
    94/100 stars

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    Related Articles

    Positive Control:

    Article Title: Identification of novel 1-indolyl acetate-5-nitroimidazole derivatives of combretastatin A-4 as potential tubulin polymerization inhibitors.
    Article Snippet: .. Microtubules are essential for the mitotic division of cells and have become an attractive target for anti-tumour drugs due to the increased incidence of cancer and significant mitosis rate of tumour cells. .. Microtubules are essential for the mitotic division of cells and have become an attractive target for anti-tumour drugs due to the increased incidence of cancer and significant mitosis rate of tumour cells.

    Article Title: Molecular, Biological and Structural Features of VL CDR-1 Rb44 Peptide, Which Targets the Microtubule Network in Melanoma Cells
    Article Snippet: .. The microtubule depolymerizing CA4 (combretastatin A4, Sigma-Adrich, St. Louis, MO) was used at 75 μM as positive control of G2/M cell cycle arrest. .. Transmission Electron Microscopy B16F10-Nex2 cells (1 × 106 ) were seeded in 6-well plates.

    Generated:

    Article Title: Human iPSC-Derived Endothelial Cell Sprouting Assay in Synthetic Hydrogel Arrays
    Article Snippet: .. Inhibitor stock solutions were generated for SU5416 (20 mM; Sigma), temsirolimus (20 mM; Sigma), sunitinib malate (20 mM; Sigma), SB-3CT (16 mM; Sigma), nilotinib (20 mM; Selleck Chemicals), vatalanib (20 mM; Selleck Chemicals), combretastatin A4 (20 mM; Sigma), withaferin A (20 mM; Sigma), and (+-)-thalidomide (100 mM; Sigma). .. Compound plates containing the ToxCast Phase I and II chemical library[ ] dissolved at 6–20 mM in DMSO were provided via Materials Transfer Agreement by the US Environmental Protection Agency (Research Triangle Park, NC).

    Cell Culture:

    Article Title: Identification of novel 1-indolyl acetate-5-nitroimidazole derivatives of combretastatin A-4 as potential tubulin polymerization inhibitors.
    Article Snippet: .. Microtubules are essential for the mitotic division of cells and have become an attractive target for anti-tumour drugs due to the increased incidence of cancer and significant mitosis rate of tumour cells. .. Microtubules are essential for the mitotic division of cells and have become an attractive target for anti-tumour drugs due to the increased incidence of cancer and significant mitosis rate of tumour cells.

    Concentration Assay:

    Article Title: Identification of novel 1-indolyl acetate-5-nitroimidazole derivatives of combretastatin A-4 as potential tubulin polymerization inhibitors.
    Article Snippet: .. Microtubules are essential for the mitotic division of cells and have become an attractive target for anti-tumour drugs due to the increased incidence of cancer and significant mitosis rate of tumour cells. .. Microtubules are essential for the mitotic division of cells and have become an attractive target for anti-tumour drugs due to the increased incidence of cancer and significant mitosis rate of tumour cells.

    Incubation:

    Article Title: Identification of novel 1-indolyl acetate-5-nitroimidazole derivatives of combretastatin A-4 as potential tubulin polymerization inhibitors.
    Article Snippet: .. Microtubules are essential for the mitotic division of cells and have become an attractive target for anti-tumour drugs due to the increased incidence of cancer and significant mitosis rate of tumour cells. .. Microtubules are essential for the mitotic division of cells and have become an attractive target for anti-tumour drugs due to the increased incidence of cancer and significant mitosis rate of tumour cells.

    other:

    Article Title: Comparison of effects of anti-angiogenic agents in the zebrafish efficacy–toxicity model for translational anti-angiogenic drug discovery
    Article Snippet: Materials The anti-angiogenic compounds SU5416, combretastatin, thalidomide, TNP-470, flavopiridol, suramin, paclitaxel, and sorafenib were purchased from Sigma-Aldrich Co. (St Louis, MO, USA); vatalanib, motesanib, pazopanib, tivozanib, and vandetanib were purchased from LC Laboratories (Woburn, MA, USA).

    Activity Assay:

    Article Title: Structurally simplified biphenyl combretastatin A4 derivatives retain in vitro anti-cancer activity dependent on mitotic arrest
    Article Snippet: .. Reagents Two biphenyl analogues (MP5-F9 and MP5-G9) of CA4 were prepared as previously reported [ ] and their biological activity was compared to CA4 (Sigma-Aldrich Canada, Cat. No. C7744, Mississauga, ON, Canada). .. Reversine (Sigma-Aldrich Canada, Cat. No. R3904, Mississauga, ON, Canada) and RO-3306 (Sigma-Aldrich Canada Cat. No. SML0569, Mississauga, ON, Canada), small molecule inhibitors known to prevent mitotic arrest, were used to test the causal connection between mitotic arrest and apoptosis.

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  • 94
    Millipore combretastatin a 4
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