Structured Review

Ipsen Group cognate snare syntaxin sx
Cognate Snare Syntaxin Sx, supplied by Ipsen Group, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 86 stars, based on 1 article reviews
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cognate snare syntaxin sx - by Bioz Stars, 2021-05
86/100 stars

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Article Title: Revisiting interaction specificity reveals neuronal and adipocyte Munc18 membrane fusion regulatory proteins differ in their binding interactions with partner SNARE Syntaxins
Article Snippet: Munc18c and Munc18a bind “non-cognate” Sx partners According to the current paradigm, the interaction between Munc18 and Sx is specific such that Munc18a binds Sx1 but not Sx4, while the homologous protein Munc18c binds Sx4 but not Sx1.

Article Title: Revisiting interaction specificity reveals neuronal and adipocyte Munc18 membrane fusion regulatory proteins differ in their binding interactions with partner SNARE Syntaxins
Article Snippet: Taken together, our data indicate that the current paradigm for Munc18 and Sx interaction specificity needs to be revised [ , – ].

Binding Assay:

Article Title: Revisiting interaction specificity reveals neuronal and adipocyte Munc18 membrane fusion regulatory proteins differ in their binding interactions with partner SNARE Syntaxins
Article Snippet: .. This is in part due to different binding modes that Munc18 displays with its cognate Sx. .. One binding mode involves the binding of multiple Sx domains to the Munc18 protein and appears to be consistent with a closed or non-fusion competent state of the Sx [ , ].

Article Title: Revisiting interaction specificity reveals neuronal and adipocyte Munc18 membrane fusion regulatory proteins differ in their binding interactions with partner SNARE Syntaxins
Article Snippet: This suggests two possibilities—either there is no specificity for the Munc18:Sx interaction between these pairs of proteins or the specificity is defined by interactions other than the N-peptide binding site. .. The present work revisits the specificity of interactions between Munc18 and Sx proteins, using in vitro binding experiments focusing on Munc18a and Munc18c and soluble truncated forms of Sx4 and Sx1. ..

In Vitro:

Article Title: Revisiting interaction specificity reveals neuronal and adipocyte Munc18 membrane fusion regulatory proteins differ in their binding interactions with partner SNARE Syntaxins
Article Snippet: This suggests two possibilities—either there is no specificity for the Munc18:Sx interaction between these pairs of proteins or the specificity is defined by interactions other than the N-peptide binding site. .. The present work revisits the specificity of interactions between Munc18 and Sx proteins, using in vitro binding experiments focusing on Munc18a and Munc18c and soluble truncated forms of Sx4 and Sx1. ..

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    Ipsen Group cognate snare syntaxin sx
    Cognate Snare Syntaxin Sx, supplied by Ipsen Group, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cognate snare syntaxin sx/product/Ipsen Group
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    cognate snare syntaxin sx - by Bioz Stars, 2021-05
    86/100 stars
      Buy from Supplier

    86
    Ipsen Group cognate syntaxin sx
    Cognate Syntaxin Sx, supplied by Ipsen Group, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cognate syntaxin sx/product/Ipsen Group
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    cognate syntaxin sx - by Bioz Stars, 2021-05
    86/100 stars
      Buy from Supplier

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