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clusterin elisa kit  (R&D Systems)


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    Structured Review

    R&D Systems clusterin elisa kit
    Clusterin Elisa Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/clusterin elisa kit/product/R&D Systems
    Average 86 stars, based on 1 article reviews
    clusterin elisa kit - by Bioz Stars, 2025-07
    86/100 stars

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    Image Search Results


    Secreted clusterin (sCLU; outlined in orange): A binds and prevents the aggregation of Aβ; B interacts with LRP2 to transport Aβ species across the blood-brain barrier into the periphery; C interacts with TREM2 to transport Aβ into glial cells for lysosomal degradation; D prevents assembly of the membrane attack complex and associated apoptosis; E interacts with VGLUT1 to stimulate excitatory neurotransmission; F interacts with APOER2 and VLDR to induce reelin signaling, which decreases tau phosphorylation by inhibiting GSK3β; and G prevents oxidative stress and associated CASP3-mediated apoptosis. Illustrations were created using Biorender.com.

    Journal: Npj Drug Discovery

    Article Title: Discovery of a small molecule secreted clusterin enhancer that improves memory in Alzheimer’s disease mice

    doi: 10.1038/s44386-025-00009-2

    Figure Lengend Snippet: Secreted clusterin (sCLU; outlined in orange): A binds and prevents the aggregation of Aβ; B interacts with LRP2 to transport Aβ species across the blood-brain barrier into the periphery; C interacts with TREM2 to transport Aβ into glial cells for lysosomal degradation; D prevents assembly of the membrane attack complex and associated apoptosis; E interacts with VGLUT1 to stimulate excitatory neurotransmission; F interacts with APOER2 and VLDR to induce reelin signaling, which decreases tau phosphorylation by inhibiting GSK3β; and G prevents oxidative stress and associated CASP3-mediated apoptosis. Illustrations were created using Biorender.com.

    Article Snippet: The Mouse Clusterin ELISA Kit (Cat#ab199079, Abcam) was performed according to the manufacturer’s protocol.

    Techniques: Membrane, Phospho-proteomics