Journal: Journal of Antimicrobial Chemotherapy
Article Title: Oral ciprofloxacin biofilm activity in a catheter-associated urinary tract infection model
doi: 10.1093/jac/dkae424
Figure Lengend Snippet: ATCC isolates in CA-UTI model. Drug-free incubation in the model for the initial 72 h, followed by 12-hourly ciprofloxacin administration for 72 h, followed by 24 h incubation without ciprofloxacin administration. Each biofilm mass data point is reflective of a separate bladder-catheter compartment set-up. Error bars represent the standard deviation of the mean biofilm mass quantification tested in triplicate. The drug-free experiment was performed separately from the ciprofloxacin exposure experiment. Scanning electron microscopy images of the dissected catheter (Figure ) were taken at 72 and 144 h. Dotted line represents the limit of detection of the quantitative cultures. Eco, Escherichia coli ; Kpn, Klebsiella pneumoniae ; Pae, Pseudomonas aeruginosa . This figure appears in colour in the online version of JAC and in black and white in the print version of JAC .
Article Snippet: Emergence of ciprofloxacin resistance was identified in 10 isolates (PAE-50210, PAE-81458, PAE-ATCC-27853, PAE-91643, PAE-44425, PAE-92669, PAE-60707, PAE-60905, PAE-27501, PAE-87386).
Techniques: Incubation, Standard Deviation, Electron Microscopy