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chga af405 novus  (Novus Biologicals)


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    Novus Biologicals chga af405 novus
    Chga Af405 Novus, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 94/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/chga af405 novus/product/Novus Biologicals
    Average 94 stars, based on 4 article reviews
    chga af405 novus - by Bioz Stars, 2026-06
    94/100 stars

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    Histopathological and immunohistochemical findings of the cervical tumor. (A) H&E staining (ocular, ×10; objective, ×4; final magnification, ×40) showing mixed histology. (B) H&E staining (ocular, ×10; objective, ×10; final magnification, ×100) revealing coexistence of adenocarcinoma and neuroendocrine components. (C) H&E staining of the neuroendocrine component (ocular, ×10; objective, ×40; final magnification, ×400). (D-L) Immunohistochemical analysis of the neuroendocrine component (ocular, ×10; objective, ×40; final magnification, ×400) revealing the following: (D) Synaptophysin, positive; (E) chromogranin A, positive; (F) p16, positive; (G) yes-associated protein 1, negative; (H) thyroid transcription factor-1, negative; (I) retinoblastoma protein, wild-type expression; (J) paired box 8, negative; (K) Ki-67, low proliferative activity; and (L) Ki-67, hotspot with high proliferative activity.

    Journal: Oncology Letters

    Article Title: Proliferative escalation and possible neuroendocrine carcinoma transformation in pulmonary metastases of a cervical neuroendocrine tumor: A case report

    doi: 10.3892/ol.2026.15501

    Figure Lengend Snippet: Histopathological and immunohistochemical findings of the cervical tumor. (A) H&E staining (ocular, ×10; objective, ×4; final magnification, ×40) showing mixed histology. (B) H&E staining (ocular, ×10; objective, ×10; final magnification, ×100) revealing coexistence of adenocarcinoma and neuroendocrine components. (C) H&E staining of the neuroendocrine component (ocular, ×10; objective, ×40; final magnification, ×400). (D-L) Immunohistochemical analysis of the neuroendocrine component (ocular, ×10; objective, ×40; final magnification, ×400) revealing the following: (D) Synaptophysin, positive; (E) chromogranin A, positive; (F) p16, positive; (G) yes-associated protein 1, negative; (H) thyroid transcription factor-1, negative; (I) retinoblastoma protein, wild-type expression; (J) paired box 8, negative; (K) Ki-67, low proliferative activity; and (L) Ki-67, hotspot with high proliferative activity.

    Article Snippet: For the immunostaining shown in , chromogranin A (catalog no. 412751; Nichirei) was used at a dilution of 1:1.

    Techniques: Immunohistochemical staining, Staining, Expressing, Activity Assay

    Histopathological and immunohistochemical findings of the right middle lobe lung tumor. (A-C) H&E staining of the resected specimen showing exclusively neuroendocrine tumor components. (A) Ocular, ×10; objective, ×4; final magnification, ×40. (B) Ocular, ×10; objective, ×10; final magnification, ×100. (C) Ocular, ×10; objective, ×40; final magnification, ×400. (D) Chromogranin A immunostaining (ocular, ×10; objective, ×40; final magnification, ×400) demonstrating positive expression in tumor cells.

    Journal: Oncology Letters

    Article Title: Proliferative escalation and possible neuroendocrine carcinoma transformation in pulmonary metastases of a cervical neuroendocrine tumor: A case report

    doi: 10.3892/ol.2026.15501

    Figure Lengend Snippet: Histopathological and immunohistochemical findings of the right middle lobe lung tumor. (A-C) H&E staining of the resected specimen showing exclusively neuroendocrine tumor components. (A) Ocular, ×10; objective, ×4; final magnification, ×40. (B) Ocular, ×10; objective, ×10; final magnification, ×100. (C) Ocular, ×10; objective, ×40; final magnification, ×400. (D) Chromogranin A immunostaining (ocular, ×10; objective, ×40; final magnification, ×400) demonstrating positive expression in tumor cells.

    Article Snippet: For the immunostaining shown in , chromogranin A (catalog no. 412751; Nichirei) was used at a dilution of 1:1.

    Techniques: Immunohistochemical staining, Staining, Immunostaining, Expressing

    Histopathological and immunohistochemical findings of the left upper lobe lung tumor. (A) Low-power view of H&E staining (scale bar, 2.5 mm). (B) H&E staining (ocular, ×10; objective, ×10; final magnification, ×100). (C) H&E staining (ocular, ×10; objective, ×20; final magnification, ×200). (A-C) The tumor consisted predominantly of NET components but with areas of increased chromatin and a higher nuclear-to-cytoplasmic ratio, suggesting the presence of NEC components. (D-K) Immunohistochemical analysis (ocular, ×10; objective, ×10; final magnification, ×100) revealed the following: (D) Synaptophysin, positive in NET areas but weaker in suspected NEC areas; (E) chromogranin A, positive; (F) p16, positive; (G) yes-associated protein 1, negative; (H) thyroid transcription factor-1, negative in NET areas but focally positive in suspected NEC areas; (I) retinoblastoma protein, wild-type expression; (J) paired box 8, negative; and (K) Ki-67, high proliferative index in suspected NEC areas. NEC, neuroendocrine carcinoma; NET, neuroendocrine tumor.

    Journal: Oncology Letters

    Article Title: Proliferative escalation and possible neuroendocrine carcinoma transformation in pulmonary metastases of a cervical neuroendocrine tumor: A case report

    doi: 10.3892/ol.2026.15501

    Figure Lengend Snippet: Histopathological and immunohistochemical findings of the left upper lobe lung tumor. (A) Low-power view of H&E staining (scale bar, 2.5 mm). (B) H&E staining (ocular, ×10; objective, ×10; final magnification, ×100). (C) H&E staining (ocular, ×10; objective, ×20; final magnification, ×200). (A-C) The tumor consisted predominantly of NET components but with areas of increased chromatin and a higher nuclear-to-cytoplasmic ratio, suggesting the presence of NEC components. (D-K) Immunohistochemical analysis (ocular, ×10; objective, ×10; final magnification, ×100) revealed the following: (D) Synaptophysin, positive in NET areas but weaker in suspected NEC areas; (E) chromogranin A, positive; (F) p16, positive; (G) yes-associated protein 1, negative; (H) thyroid transcription factor-1, negative in NET areas but focally positive in suspected NEC areas; (I) retinoblastoma protein, wild-type expression; (J) paired box 8, negative; and (K) Ki-67, high proliferative index in suspected NEC areas. NEC, neuroendocrine carcinoma; NET, neuroendocrine tumor.

    Article Snippet: For the immunostaining shown in , chromogranin A (catalog no. 412751; Nichirei) was used at a dilution of 1:1.

    Techniques: Immunohistochemical staining, Staining, Expressing