Structured Review

Santa Cruz Biotechnology canertinib
Canertinib, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/canertinib/product/Santa Cruz Biotechnology
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
canertinib - by Bioz Stars, 2020-09
93/100 stars

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Concentration Assay:

Article Title: ErbB4 tyrosine kinase inhibition impairs neuromuscular development in zebrafish embryos
Article Snippet: .. ErbB tyrosine kinase inhibitors To block ErbB kinase activity in the embryos, 10 µM of tyrosine kinase inhibitors AG 1478 (Calbiochem), erlotinib, gefitinib, lapatinib, afatinib, neratinib, canertinib (all from Santa-Cruz Biotechnologies), osimertinib, and dacomitinib (both from Cayman Chemical), diluted in DMSO, or DMSO alone was applied in E3 medium at 8 hpf, except as indicated for experimentation shown in D. The final concentration of DMSO was 0.1% of the culture medium. .. Morpholino antisense oligonucleotides To block endogenous expression of erbb4a in zebrafish embryos, a morpholino antisense oligonucleotide targeting the translation initiation site of the erbb4a mRNA (5′-AGAAGGAAGCGAACCGGCCACATTT-3′) and a standard control morpholino targeting a mutated splice site of human β-globin mRNA (5′-CCTCTTACCTC AGTTACAATTTATA-3′) were purchased from Gene Tools LLC.

Activity Assay:

Article Title: ErbB4 tyrosine kinase inhibition impairs neuromuscular development in zebrafish embryos
Article Snippet: .. ErbB tyrosine kinase inhibitors To block ErbB kinase activity in the embryos, 10 µM of tyrosine kinase inhibitors AG 1478 (Calbiochem), erlotinib, gefitinib, lapatinib, afatinib, neratinib, canertinib (all from Santa-Cruz Biotechnologies), osimertinib, and dacomitinib (both from Cayman Chemical), diluted in DMSO, or DMSO alone was applied in E3 medium at 8 hpf, except as indicated for experimentation shown in D. The final concentration of DMSO was 0.1% of the culture medium. .. Morpholino antisense oligonucleotides To block endogenous expression of erbb4a in zebrafish embryos, a morpholino antisense oligonucleotide targeting the translation initiation site of the erbb4a mRNA (5′-AGAAGGAAGCGAACCGGCCACATTT-3′) and a standard control morpholino targeting a mutated splice site of human β-globin mRNA (5′-CCTCTTACCTC AGTTACAATTTATA-3′) were purchased from Gene Tools LLC.

Blocking Assay:

Article Title: ErbB4 tyrosine kinase inhibition impairs neuromuscular development in zebrafish embryos
Article Snippet: .. ErbB tyrosine kinase inhibitors To block ErbB kinase activity in the embryos, 10 µM of tyrosine kinase inhibitors AG 1478 (Calbiochem), erlotinib, gefitinib, lapatinib, afatinib, neratinib, canertinib (all from Santa-Cruz Biotechnologies), osimertinib, and dacomitinib (both from Cayman Chemical), diluted in DMSO, or DMSO alone was applied in E3 medium at 8 hpf, except as indicated for experimentation shown in D. The final concentration of DMSO was 0.1% of the culture medium. .. Morpholino antisense oligonucleotides To block endogenous expression of erbb4a in zebrafish embryos, a morpholino antisense oligonucleotide targeting the translation initiation site of the erbb4a mRNA (5′-AGAAGGAAGCGAACCGGCCACATTT-3′) and a standard control morpholino targeting a mutated splice site of human β-globin mRNA (5′-CCTCTTACCTC AGTTACAATTTATA-3′) were purchased from Gene Tools LLC.

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    Santa Cruz Biotechnology canertinib
    Canertinib, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/canertinib/product/Santa Cruz Biotechnology
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    canertinib - by Bioz Stars, 2020-09
    93/100 stars
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