canertinib  (Millipore)


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    Name:
    CI 1033
    Description:

    Catalog Number:
    c7249
    Price:
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    Structured Review

    Millipore canertinib
    CI 1033

    https://www.bioz.com/result/canertinib/product/Millipore
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    canertinib - by Bioz Stars, 2020-09
    93/100 stars

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    Related Articles

    XTT Assay:

    Article Title: Activity Assay of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Triple-Negative Breast Cancer Cells Using Peptide-Conjugated Magnetic Beads
    Article Snippet: .. After 24 h, erlotinib, gefitinib, CL-387,785, CI-1033, and BIBW-2992 at varying concentrations were added and the cells were incubated further for 48 h. The cells were then washed with PBS and cell viability was measured using a XTT assay kit (Sigma). .. A dose–response curve fit was generated (3 parameter fit in GraphPad Prism) by plotting inhibition of cell growth against log concentration of inhibitors.

    Incubation:

    Article Title: The fibroblast-derived paracrine factor neuregulin-1 has a novel role in regulating the constitutive color and melanocyte function in human skin
    Article Snippet: .. For the experiments where the MelanoDerms were treated with NRG-1 and/or various pan-ErbB inhibitors, the dark MelanoDerms were first incubated with a pan-ErbB inhibitor (0.5 μM C39, EMD Chemicals, Gibbistown, NJ or 2 μM CI-1033, Selleck Chemicals LLC, US) for 30 minutes or with vehicle (DMSO) only before treatment with 50 ng/ml NRG-1; identical amounts of DMSO (0.02%) were added to all samples. .. Fibroblast cultures in 100-mm dishes were solubilized in appropriate volumes of mammalian protein extraction reagent (M-PER; Pierce Biotechnology, Rockford, IL) containing a protease inhibitor mixture (Roche, Mannheim, Germany) and phosphatase inhibitors.

    Article Title: Activity Assay of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Triple-Negative Breast Cancer Cells Using Peptide-Conjugated Magnetic Beads
    Article Snippet: .. After 24 h, erlotinib, gefitinib, CL-387,785, CI-1033, and BIBW-2992 at varying concentrations were added and the cells were incubated further for 48 h. The cells were then washed with PBS and cell viability was measured using a XTT assay kit (Sigma). .. A dose–response curve fit was generated (3 parameter fit in GraphPad Prism) by plotting inhibition of cell growth against log concentration of inhibitors.

    other:

    Article Title: Lipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinib
    Article Snippet: Every other day, cells were treated with indicated concentrations of gefitinib, CI-1033 or lovastatin (EMD Biosciences, Gibbstown, NJ) alone or in combination in growth medium.

    Article Title: The Effect of Canertinib on Sensitivity of Cytotoxic Drugs in Tamoxifen-Resistant Breast Cancer Cells In Vitro
    Article Snippet: Clinical grade canertinib (CI-1033) and cytotoxic drugs (paclitaxel, etoposide, vinorelbine, and daunorubicin) were purchased from Sigma Chemical Co. (Sigma-Aldrich, Egypt).

    Article Title: The Effect of Canertinib on Sensitivity of Cytotoxic Drugs in Tamoxifen-Resistant Breast Cancer Cells In Vitro
    Article Snippet: Materials Clinical grade canertinib (CI-1033) and cytotoxic drugs (paclitaxel, etoposide, vinorelbine, and daunorubicin) were purchased from Sigma Chemical Co. (Sigma-Aldrich, Egypt).

    Article Title: Binding-induced, turn-on fluorescence of the EGFR/ERBB kinase inhibitor, lapatinib
    Article Snippet: Inhibitors and bioreagents were obtained from commercial suppliers: lapatinib ditosylate (Selleck Chemicals); canertinib and adenosine 5′-(β, γ-imido) triphosphate (Sigma-Aldrich); ERBB2 kinase domain fragment Q679-V1255 (Biaffin); BSA and mouse anti-ERBB2 (Calbiochem); Alexa Fluor546 goat antimouse (Life Technologies).

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  • 93
    Millipore pan erbb inhibitor
    Effect of <t>pan-ErbB</t> inhibitors on NRG-1 action on human melanocytes and MelanoDerms. ( A ) HEM-DP were treated for 9 days with 50 ng/ml NRG-1 in the presence of <t>C39</t> (0.5 μM) or CI-1033 (2 μM) or vehicle (DMSO) alone. The results are the average
    Pan Erbb Inhibitor, supplied by Millipore, used in various techniques. Bioz Stars score: 93/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pan erbb inhibitor/product/Millipore
    Average 93 stars, based on 2 article reviews
    Price from $9.99 to $1999.99
    pan erbb inhibitor - by Bioz Stars, 2020-09
    93/100 stars
      Buy from Supplier

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    Effect of pan-ErbB inhibitors on NRG-1 action on human melanocytes and MelanoDerms. ( A ) HEM-DP were treated for 9 days with 50 ng/ml NRG-1 in the presence of C39 (0.5 μM) or CI-1033 (2 μM) or vehicle (DMSO) alone. The results are the average

    Journal: Journal of Cell Science

    Article Title: The fibroblast-derived paracrine factor neuregulin-1 has a novel role in regulating the constitutive color and melanocyte function in human skin

    doi: 10.1242/jcs.064774

    Figure Lengend Snippet: Effect of pan-ErbB inhibitors on NRG-1 action on human melanocytes and MelanoDerms. ( A ) HEM-DP were treated for 9 days with 50 ng/ml NRG-1 in the presence of C39 (0.5 μM) or CI-1033 (2 μM) or vehicle (DMSO) alone. The results are the average

    Article Snippet: For the experiments where the MelanoDerms were treated with NRG-1 and/or various pan-ErbB inhibitors, the dark MelanoDerms were first incubated with a pan-ErbB inhibitor (0.5 μM C39, EMD Chemicals, Gibbistown, NJ or 2 μM CI-1033, Selleck Chemicals LLC, US) for 30 minutes or with vehicle (DMSO) only before treatment with 50 ng/ml NRG-1; identical amounts of DMSO (0.02%) were added to all samples.

    Techniques: