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U73122 PLC ca2 response
Ca2 Response, supplied by U73122 PLC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ca2 response/product/U73122 PLC
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
ca2 response - by Bioz Stars, 2021-05
86/100 stars

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Article Title: Chemerin-induced arterial contraction is Gi- and calcium-dependent
Article Snippet: Pertussis toxin (Gi inhibitor), verapamil (L-type Ca2+ channel inhibitor), PP1 (Src inhibitor), and Y27632 (Rho kinase inhibitor) reduced both calcium influx and isometric contraction to chemerin-9 but PD098059 (Erk MAPK inhibitor) and U73122 (PLC inhibitor) had little to no effect on either measure of chemerin signaling.

Article Title: A mixture of anatase and rutile TiO2 nanoparticles induces histamine secretion in mast cells
Article Snippet: In order to test the involvement of secondary messenger molecules in intensifying a Ca2+ response, U73122 (PLC blocker) (10 μM; Sigma-Aldrich, MO, USA), Aminoethoxydiphenyl borate (2-APB) (50 μM; Sigma-Aldrich, MO, USA) and Xestospongin C (IP3 receptor blockers) (20 μM; VWR, CA, USA) were pre-incubated with cells prior to TiO2 NP exposure [ , ].

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Article Title: Activation of Alpha-1 Adrenergic Receptors Increases Cytosolic Calcium in Neurons of the Paraventricular Nucleus of the Hypothalamus
Article Snippet: .. The contribution of these pathways in the magnitude of [Ca2+ ]i increase by PE was examined by applying PE in the presence of the PLC blocker U73122 (PLC Ø, 1 μM), the PKC blocker Chelerythrine Chloride (PKC Ø, 1 μM), or the IP3 receptor blocker Xestospongin C (IP3 R Ø, 1 μM). ..

Article Title: Trace amine–associated receptor 1 (TAAR1) promotes anti-diabetic signaling in insulin-secreting cells
Article Snippet: Likewise, reloading of intracellular calcium stores was partially required for activation of pERK1/2, as blockade of the sarco/endoplasmic reticulum Ca2+ -ATPase (SERCA) pump with thapsigargin was able to reduce ERK phosphorylation in response to these agents ( A ). .. PLC-β, a common mediator of calcium signaling through Gq - and Gi -coupled receptors, however, was not required for TAAR1-initiated ERK1/2 phosphorylation, as the U73122 PLC-β inhibitor had no effect on T1 AM or forskolin-mediated ERK1/2 phosphorylation ( B ), an agonist of protease-activated receptor 2 (PAR2), a known Gq -coupled receptor expressed in the pancreas , confirming the efficacy of U73122 in these insulin-secreting cells. .. Ca2+/ Calmodulin (CaM) kinase–dependent signaling has been shown previously to regulate Raf/MEK/ERK pathways in certain cell types , providing a possible link between intracellular calcium and downstream ERK1/2 phosphorylation.

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    U73122 PLC ca2 response
    Ca2 Response, supplied by U73122 PLC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ca2 response/product/U73122 PLC
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    ca2 response - by Bioz Stars, 2021-05
    86/100 stars
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