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cannabichromene cbc  (Alomone Labs)


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    Alomone Labs cannabichromene cbc
    A Concentration-response curves for the inhibition of hNa V 1.7 channels by cannabidiol (CBD; circles), Δ⁹-tetrahydrocannabinol (THC; squares), <t>cannabichromene</t> <t>(CBC;</t> triangles), and cannabigerol (CBG; diamonds). Peak current amplitude was normalized to the current before drug application (I X /I Before ) and plotted against the cannabinoid concentration. Solid lines represent fits of the data to the Hill equation. Each data point represents the mean ± SEM from at least n = 6 cells. hNa V 1.7: [CBD: IC 50 = 3.4 ± 0.3 µM; THC: IC 50 = 8.4 ± 0.8 µM; CBC: IC 50 = 5.1 ± 0.7 µM; CBG: IC 50 = 3.3 ± 0.3 µM]. B Same as ( A ), but for hNa V 1.8 channels. hNa V 1.8: [CBD: IC 50 = 0.8 ± 0.1 µM; THC: IC 50 = 9.5 ± 0.6 µM; CBC: IC 50 = 14.4 ± 1.4 µM; CBG: IC 50 = 0.9 ± 0.1 µM].
    Cannabichromene Cbc, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/c-315/pmc13125304-32-0-5?v=Alomone+Labs
    Average 94 stars, based on 1 article reviews
    cannabichromene cbc - by Bioz Stars, 2026-07
    94/100 stars

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    1) Product Images from "The psychoactive cannabinoid THC inhibits peripheral nociceptors by targeting Na V 1.7 and Na V 1.8 nociceptive sodium channels"

    Article Title: The psychoactive cannabinoid THC inhibits peripheral nociceptors by targeting Na V 1.7 and Na V 1.8 nociceptive sodium channels

    Journal: Neuropsychopharmacology

    doi: 10.1038/s41386-026-02355-9

    A Concentration-response curves for the inhibition of hNa V 1.7 channels by cannabidiol (CBD; circles), Δ⁹-tetrahydrocannabinol (THC; squares), cannabichromene (CBC; triangles), and cannabigerol (CBG; diamonds). Peak current amplitude was normalized to the current before drug application (I X /I Before ) and plotted against the cannabinoid concentration. Solid lines represent fits of the data to the Hill equation. Each data point represents the mean ± SEM from at least n = 6 cells. hNa V 1.7: [CBD: IC 50 = 3.4 ± 0.3 µM; THC: IC 50 = 8.4 ± 0.8 µM; CBC: IC 50 = 5.1 ± 0.7 µM; CBG: IC 50 = 3.3 ± 0.3 µM]. B Same as ( A ), but for hNa V 1.8 channels. hNa V 1.8: [CBD: IC 50 = 0.8 ± 0.1 µM; THC: IC 50 = 9.5 ± 0.6 µM; CBC: IC 50 = 14.4 ± 1.4 µM; CBG: IC 50 = 0.9 ± 0.1 µM].
    Figure Legend Snippet: A Concentration-response curves for the inhibition of hNa V 1.7 channels by cannabidiol (CBD; circles), Δ⁹-tetrahydrocannabinol (THC; squares), cannabichromene (CBC; triangles), and cannabigerol (CBG; diamonds). Peak current amplitude was normalized to the current before drug application (I X /I Before ) and plotted against the cannabinoid concentration. Solid lines represent fits of the data to the Hill equation. Each data point represents the mean ± SEM from at least n = 6 cells. hNa V 1.7: [CBD: IC 50 = 3.4 ± 0.3 µM; THC: IC 50 = 8.4 ± 0.8 µM; CBC: IC 50 = 5.1 ± 0.7 µM; CBG: IC 50 = 3.3 ± 0.3 µM]. B Same as ( A ), but for hNa V 1.8 channels. hNa V 1.8: [CBD: IC 50 = 0.8 ± 0.1 µM; THC: IC 50 = 9.5 ± 0.6 µM; CBC: IC 50 = 14.4 ± 1.4 µM; CBG: IC 50 = 0.9 ± 0.1 µM].

    Techniques Used: Concentration Assay, Inhibition



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    A Concentration-response curves for the inhibition of hNa V 1.7 channels by cannabidiol (CBD; circles), Δ⁹-tetrahydrocannabinol (THC; squares), <t>cannabichromene</t> <t>(CBC;</t> triangles), and cannabigerol (CBG; diamonds). Peak current amplitude was normalized to the current before drug application (I X /I Before ) and plotted against the cannabinoid concentration. Solid lines represent fits of the data to the Hill equation. Each data point represents the mean ± SEM from at least n = 6 cells. hNa V 1.7: [CBD: IC 50 = 3.4 ± 0.3 µM; THC: IC 50 = 8.4 ± 0.8 µM; CBC: IC 50 = 5.1 ± 0.7 µM; CBG: IC 50 = 3.3 ± 0.3 µM]. B Same as ( A ), but for hNa V 1.8 channels. hNa V 1.8: [CBD: IC 50 = 0.8 ± 0.1 µM; THC: IC 50 = 9.5 ± 0.6 µM; CBC: IC 50 = 14.4 ± 1.4 µM; CBG: IC 50 = 0.9 ± 0.1 µM].
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    A Concentration-response curves for the inhibition of hNa V 1.7 channels by cannabidiol (CBD; circles), Δ⁹-tetrahydrocannabinol (THC; squares), <t>cannabichromene</t> <t>(CBC;</t> triangles), and cannabigerol (CBG; diamonds). Peak current amplitude was normalized to the current before drug application (I X /I Before ) and plotted against the cannabinoid concentration. Solid lines represent fits of the data to the Hill equation. Each data point represents the mean ± SEM from at least n = 6 cells. hNa V 1.7: [CBD: IC 50 = 3.4 ± 0.3 µM; THC: IC 50 = 8.4 ± 0.8 µM; CBC: IC 50 = 5.1 ± 0.7 µM; CBG: IC 50 = 3.3 ± 0.3 µM]. B Same as ( A ), but for hNa V 1.8 channels. hNa V 1.8: [CBD: IC 50 = 0.8 ± 0.1 µM; THC: IC 50 = 9.5 ± 0.6 µM; CBC: IC 50 = 14.4 ± 1.4 µM; CBG: IC 50 = 0.9 ± 0.1 µM].
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    A Concentration-response curves for the inhibition of hNa V 1.7 channels by cannabidiol (CBD; circles), Δ⁹-tetrahydrocannabinol (THC; squares), <t>cannabichromene</t> <t>(CBC;</t> triangles), and cannabigerol (CBG; diamonds). Peak current amplitude was normalized to the current before drug application (I X /I Before ) and plotted against the cannabinoid concentration. Solid lines represent fits of the data to the Hill equation. Each data point represents the mean ± SEM from at least n = 6 cells. hNa V 1.7: [CBD: IC 50 = 3.4 ± 0.3 µM; THC: IC 50 = 8.4 ± 0.8 µM; CBC: IC 50 = 5.1 ± 0.7 µM; CBG: IC 50 = 3.3 ± 0.3 µM]. B Same as ( A ), but for hNa V 1.8 channels. hNa V 1.8: [CBD: IC 50 = 0.8 ± 0.1 µM; THC: IC 50 = 9.5 ± 0.6 µM; CBC: IC 50 = 14.4 ± 1.4 µM; CBG: IC 50 = 0.9 ± 0.1 µM].
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    A Concentration-response curves for the inhibition of hNa V 1.7 channels by cannabidiol (CBD; circles), Δ⁹-tetrahydrocannabinol (THC; squares), <t>cannabichromene</t> <t>(CBC;</t> triangles), and cannabigerol (CBG; diamonds). Peak current amplitude was normalized to the current before drug application (I X /I Before ) and plotted against the cannabinoid concentration. Solid lines represent fits of the data to the Hill equation. Each data point represents the mean ± SEM from at least n = 6 cells. hNa V 1.7: [CBD: IC 50 = 3.4 ± 0.3 µM; THC: IC 50 = 8.4 ± 0.8 µM; CBC: IC 50 = 5.1 ± 0.7 µM; CBG: IC 50 = 3.3 ± 0.3 µM]. B Same as ( A ), but for hNa V 1.8 channels. hNa V 1.8: [CBD: IC 50 = 0.8 ± 0.1 µM; THC: IC 50 = 9.5 ± 0.6 µM; CBC: IC 50 = 14.4 ± 1.4 µM; CBG: IC 50 = 0.9 ± 0.1 µM].
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    Image Search Results


    A Concentration-response curves for the inhibition of hNa V 1.7 channels by cannabidiol (CBD; circles), Δ⁹-tetrahydrocannabinol (THC; squares), cannabichromene (CBC; triangles), and cannabigerol (CBG; diamonds). Peak current amplitude was normalized to the current before drug application (I X /I Before ) and plotted against the cannabinoid concentration. Solid lines represent fits of the data to the Hill equation. Each data point represents the mean ± SEM from at least n = 6 cells. hNa V 1.7: [CBD: IC 50 = 3.4 ± 0.3 µM; THC: IC 50 = 8.4 ± 0.8 µM; CBC: IC 50 = 5.1 ± 0.7 µM; CBG: IC 50 = 3.3 ± 0.3 µM]. B Same as ( A ), but for hNa V 1.8 channels. hNa V 1.8: [CBD: IC 50 = 0.8 ± 0.1 µM; THC: IC 50 = 9.5 ± 0.6 µM; CBC: IC 50 = 14.4 ± 1.4 µM; CBG: IC 50 = 0.9 ± 0.1 µM].

    Journal: Neuropsychopharmacology

    Article Title: The psychoactive cannabinoid THC inhibits peripheral nociceptors by targeting Na V 1.7 and Na V 1.8 nociceptive sodium channels

    doi: 10.1038/s41386-026-02355-9

    Figure Lengend Snippet: A Concentration-response curves for the inhibition of hNa V 1.7 channels by cannabidiol (CBD; circles), Δ⁹-tetrahydrocannabinol (THC; squares), cannabichromene (CBC; triangles), and cannabigerol (CBG; diamonds). Peak current amplitude was normalized to the current before drug application (I X /I Before ) and plotted against the cannabinoid concentration. Solid lines represent fits of the data to the Hill equation. Each data point represents the mean ± SEM from at least n = 6 cells. hNa V 1.7: [CBD: IC 50 = 3.4 ± 0.3 µM; THC: IC 50 = 8.4 ± 0.8 µM; CBC: IC 50 = 5.1 ± 0.7 µM; CBG: IC 50 = 3.3 ± 0.3 µM]. B Same as ( A ), but for hNa V 1.8 channels. hNa V 1.8: [CBD: IC 50 = 0.8 ± 0.1 µM; THC: IC 50 = 9.5 ± 0.6 µM; CBC: IC 50 = 14.4 ± 1.4 µM; CBG: IC 50 = 0.9 ± 0.1 µM].

    Article Snippet: Cannabichromene (CBC) was purchased from Alomone Labs (Jerusalem, Israel), and Cannabigerol (CBG) was purchased from Symrise AG (Germany).

    Techniques: Concentration Assay, Inhibition