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bacterial lta antibody  (Hycult Biotech)


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    Hycult Biotech bacterial lta antibody
    Microbial distribution of multifocal HCC. A, Flowchart of sample collection and study design. A total of 58 patients with multifocal HCC were enrolled in this study. Tumor nodule samples ( N = 242, 3–11/patient) and adjacent nontumor liver tissue samples ( N = 58) were collected to perform the 16S rRNA gene sequencing, WES, and bulk RNA-seq, followed by integrative analysis and functional validation. B, Alluvial plot depicting the relative abundance of microbial composition at the phylum level (top 5) within each patient. Multiple tumor nodules (right-sided) and adjacent nontumor tissues (left-sided) of each individual are separated by a white line. C, Representative image of Gram staining, <t>bacterial</t> <t>LPS,</t> and <t>LTA</t> staining in the multifocal HCC liver tissue. The quantification of positive signals is presented as mean ± SD on the right. Scale bars, 50 µm (left) and 20 µm (right). “T1–4” refers to tumor nodules. D, Representative images of transmission electron microscopy (TEM) indicating intracellular bacteria (red arrow) within multifocal HCC liver tissue. Scale bars, 2 µm (top) and 0.5 µm (bottom). ( A, Created with BioRender.com .)
    Bacterial Lta Antibody, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 94/100, based on 42 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bacterial lta antibody/product/Hycult Biotech
    Average 94 stars, based on 42 article reviews
    bacterial lta antibody - by Bioz Stars, 2026-02
    94/100 stars

    Images

    1) Product Images from "Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations"

    Article Title: Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations

    Journal: Cancer Discovery

    doi: 10.1158/2159-8290.CD-24-1259

    Microbial distribution of multifocal HCC. A, Flowchart of sample collection and study design. A total of 58 patients with multifocal HCC were enrolled in this study. Tumor nodule samples ( N = 242, 3–11/patient) and adjacent nontumor liver tissue samples ( N = 58) were collected to perform the 16S rRNA gene sequencing, WES, and bulk RNA-seq, followed by integrative analysis and functional validation. B, Alluvial plot depicting the relative abundance of microbial composition at the phylum level (top 5) within each patient. Multiple tumor nodules (right-sided) and adjacent nontumor tissues (left-sided) of each individual are separated by a white line. C, Representative image of Gram staining, bacterial LPS, and LTA staining in the multifocal HCC liver tissue. The quantification of positive signals is presented as mean ± SD on the right. Scale bars, 50 µm (left) and 20 µm (right). “T1–4” refers to tumor nodules. D, Representative images of transmission electron microscopy (TEM) indicating intracellular bacteria (red arrow) within multifocal HCC liver tissue. Scale bars, 2 µm (top) and 0.5 µm (bottom). ( A, Created with BioRender.com .)
    Figure Legend Snippet: Microbial distribution of multifocal HCC. A, Flowchart of sample collection and study design. A total of 58 patients with multifocal HCC were enrolled in this study. Tumor nodule samples ( N = 242, 3–11/patient) and adjacent nontumor liver tissue samples ( N = 58) were collected to perform the 16S rRNA gene sequencing, WES, and bulk RNA-seq, followed by integrative analysis and functional validation. B, Alluvial plot depicting the relative abundance of microbial composition at the phylum level (top 5) within each patient. Multiple tumor nodules (right-sided) and adjacent nontumor tissues (left-sided) of each individual are separated by a white line. C, Representative image of Gram staining, bacterial LPS, and LTA staining in the multifocal HCC liver tissue. The quantification of positive signals is presented as mean ± SD on the right. Scale bars, 50 µm (left) and 20 µm (right). “T1–4” refers to tumor nodules. D, Representative images of transmission electron microscopy (TEM) indicating intracellular bacteria (red arrow) within multifocal HCC liver tissue. Scale bars, 2 µm (top) and 0.5 µm (bottom). ( A, Created with BioRender.com .)

    Techniques Used: Sequencing, RNA Sequencing, Functional Assay, Biomarker Discovery, Staining, Transmission Assay, Electron Microscopy, Bacteria



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    Microbial distribution of multifocal HCC. A, Flowchart of sample collection and study design. A total of 58 patients with multifocal HCC were enrolled in this study. Tumor nodule samples ( N = 242, 3–11/patient) and adjacent nontumor liver tissue samples ( N = 58) were collected to perform the 16S rRNA gene sequencing, WES, and bulk RNA-seq, followed by integrative analysis and functional validation. B, Alluvial plot depicting the relative abundance of microbial composition at the phylum level (top 5) within each patient. Multiple tumor nodules (right-sided) and adjacent nontumor tissues (left-sided) of each individual are separated by a white line. C, Representative image of Gram staining, <t>bacterial</t> <t>LPS,</t> and <t>LTA</t> staining in the multifocal HCC liver tissue. The quantification of positive signals is presented as mean ± SD on the right. Scale bars, 50 µm (left) and 20 µm (right). “T1–4” refers to tumor nodules. D, Representative images of transmission electron microscopy (TEM) indicating intracellular bacteria (red arrow) within multifocal HCC liver tissue. Scale bars, 2 µm (top) and 0.5 µm (bottom). ( A, Created with BioRender.com .)
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    Image Search Results


    Microbial distribution of multifocal HCC. A, Flowchart of sample collection and study design. A total of 58 patients with multifocal HCC were enrolled in this study. Tumor nodule samples ( N = 242, 3–11/patient) and adjacent nontumor liver tissue samples ( N = 58) were collected to perform the 16S rRNA gene sequencing, WES, and bulk RNA-seq, followed by integrative analysis and functional validation. B, Alluvial plot depicting the relative abundance of microbial composition at the phylum level (top 5) within each patient. Multiple tumor nodules (right-sided) and adjacent nontumor tissues (left-sided) of each individual are separated by a white line. C, Representative image of Gram staining, bacterial LPS, and LTA staining in the multifocal HCC liver tissue. The quantification of positive signals is presented as mean ± SD on the right. Scale bars, 50 µm (left) and 20 µm (right). “T1–4” refers to tumor nodules. D, Representative images of transmission electron microscopy (TEM) indicating intracellular bacteria (red arrow) within multifocal HCC liver tissue. Scale bars, 2 µm (top) and 0.5 µm (bottom). ( A, Created with BioRender.com .)

    Journal: Cancer Discovery

    Article Title: Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations

    doi: 10.1158/2159-8290.CD-24-1259

    Figure Lengend Snippet: Microbial distribution of multifocal HCC. A, Flowchart of sample collection and study design. A total of 58 patients with multifocal HCC were enrolled in this study. Tumor nodule samples ( N = 242, 3–11/patient) and adjacent nontumor liver tissue samples ( N = 58) were collected to perform the 16S rRNA gene sequencing, WES, and bulk RNA-seq, followed by integrative analysis and functional validation. B, Alluvial plot depicting the relative abundance of microbial composition at the phylum level (top 5) within each patient. Multiple tumor nodules (right-sided) and adjacent nontumor tissues (left-sided) of each individual are separated by a white line. C, Representative image of Gram staining, bacterial LPS, and LTA staining in the multifocal HCC liver tissue. The quantification of positive signals is presented as mean ± SD on the right. Scale bars, 50 µm (left) and 20 µm (right). “T1–4” refers to tumor nodules. D, Representative images of transmission electron microscopy (TEM) indicating intracellular bacteria (red arrow) within multifocal HCC liver tissue. Scale bars, 2 µm (top) and 0.5 µm (bottom). ( A, Created with BioRender.com .)

    Article Snippet: The FFPE slides were deparaffinized, rehydrated, and were stained with bacterial LPS antibody [mAb WN1 222-5; #HM6011; RRID: AB_2750644; 1:200 dilution; Hycult Biotech], bacterial LTA antibody (mAb 55; #HM2048; RRID: AB_57466; 1:400 dilution; Hycult Biotech), E-cadherin (Cell Signaling Technology, Cat# 3195S, 1:1,000, RRID:AB_2291471), N-cadherin (Cell Signaling Technology, Cat# 13116S, 1:1,000, RRID:AB_2687616), Snail (ServiceBio, GB11260, 1:200), and Ki-67 (Cell Signaling Technology, Cat# 12202S, 1:1,000, RRID:AB_2620142).

    Techniques: Sequencing, RNA Sequencing, Functional Assay, Biomarker Discovery, Staining, Transmission Assay, Electron Microscopy, Bacteria