apx001a (Amplyx Pharmaceuticals)
Structured Review
Apx001a, supplied by Amplyx Pharmaceuticals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/apx001a/product/Amplyx Pharmaceuticals
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
apx001a (Amplyx Pharmaceuticals)
Structured Review
Apx001a, supplied by Amplyx Pharmaceuticals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/apx001a/product/Amplyx Pharmaceuticals
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
apx001a (Amplyx Pharmaceuticals)
Structured Review
Apx001a, supplied by Amplyx Pharmaceuticals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/apx001a/product/Amplyx Pharmaceuticals
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
apx001a (Amplyx Pharmaceuticals)
Structured Review
Apx001a, supplied by Amplyx Pharmaceuticals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/apx001a/product/Amplyx Pharmaceuticals
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
apx001a (Amplyx Pharmaceuticals)
Structured Review

Apx001a, supplied by Amplyx Pharmaceuticals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/apx001a/product/Amplyx Pharmaceuticals
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "APX001 Pharmacokinetic/Pharmacodynamic Target Determination against Aspergillus fumigatus in an In Vivo Model of Invasive Pulmonary Aspergillosis"
Article Title: APX001 Pharmacokinetic/Pharmacodynamic Target Determination against Aspergillus fumigatus in an In Vivo Model of Invasive Pulmonary Aspergillosis
Journal: Antimicrobial Agents and Chemotherapy
doi: 10.1128/AAC.02372-18

Figure Legend Snippet: In vitro activities of APX001A and select comparator antifungal agents, in vivo fitnesses in the animal model, and genetic mutations associated with drug resistance
Techniques Used: In Vitro, In Vivo, Animal Model

Figure Legend Snippet: Pharmacodynamic regression analysis of the PK/PD index free drug AUC/MEC and the in vivo effect of APX001 against six A. fumigatus strains. Each symbol represents the mean for four mice. The drug exposure data are expressed as the APX001A 24-h free drug AUC/MEC. The line drawn through the data points is the best-fit line based upon the sigmoid Emax formula (Hill equation). The horizontal dashed line represents the net stasis of the burden from the start of therapy. Points above the line represent an increase in burden, whereas those below the line represent a decrease in burden.
Techniques Used: In Vivo
apx001a (Amplyx Pharmaceuticals)
Structured Review

Apx001a, supplied by Amplyx Pharmaceuticals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/apx001a/product/Amplyx Pharmaceuticals
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "APX001 Pharmacokinetic/Pharmacodynamic Target Determination against Aspergillus fumigatus in an In Vivo Model of Invasive Pulmonary Aspergillosis"
Article Title: APX001 Pharmacokinetic/Pharmacodynamic Target Determination against Aspergillus fumigatus in an In Vivo Model of Invasive Pulmonary Aspergillosis
Journal: Antimicrobial Agents and Chemotherapy
doi: 10.1128/AAC.02372-18

Figure Legend Snippet: In vitro activities of APX001A and select comparator antifungal agents, in vivo fitnesses in the animal model, and genetic mutations associated with drug resistance
Techniques Used: In Vitro, In Vivo, Animal Model

Figure Legend Snippet: Pharmacodynamic regression analysis of the PK/PD index free drug AUC/MEC and the in vivo effect of APX001 against six A. fumigatus strains. Each symbol represents the mean for four mice. The drug exposure data are expressed as the APX001A 24-h free drug AUC/MEC. The line drawn through the data points is the best-fit line based upon the sigmoid Emax formula (Hill equation). The horizontal dashed line represents the net stasis of the burden from the start of therapy. Points above the line represent an increase in burden, whereas those below the line represent a decrease in burden.
Techniques Used: In Vivo
apx001a (Amplyx Pharmaceuticals)
Structured Review
Apx001a, supplied by Amplyx Pharmaceuticals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/apx001a/product/Amplyx Pharmaceuticals
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
239 apx001a (Amplyx Pharmaceuticals)
Structured Review
239 Apx001a, supplied by Amplyx Pharmaceuticals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/239 apx001a/product/Amplyx Pharmaceuticals
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
apx001a (Amplyx Pharmaceuticals)
Structured Review

Apx001a, supplied by Amplyx Pharmaceuticals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/apx001a/product/Amplyx Pharmaceuticals
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "APX001 and Other Gwt1 Inhibitor Prodrugs Are Effective in Experimental Coccidioides immitis Pneumonia"
Article Title: APX001 and Other Gwt1 Inhibitor Prodrugs Are Effective in Experimental Coccidioides immitis Pneumonia
Journal: Antimicrobial Agents and Chemotherapy
doi: 10.1128/AAC.01715-18

Figure Legend Snippet: In vitro susceptibility profiles
Techniques Used: In Vitro

Figure Legend Snippet: Activity of Gwt1 inhibitors versus C. immitis and C. posadasii
Techniques Used: Activity Assay
apx001a (Amplyx Pharmaceuticals)
Structured Review
Apx001a, supplied by Amplyx Pharmaceuticals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/apx001a/product/Amplyx Pharmaceuticals
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99