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kchip2  (Alomone Labs)


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    Alomone Labs kchip2
    Kchip2, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 11 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/apc-142/pm41490034-185-39-41?v=Alomone+Labs
    Average 94 stars, based on 11 article reviews
    kchip2 - by Bioz Stars, 2026-07
    94/100 stars

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    A: Outward K + currents recorded from control (black) and HFD (red) mouse ventricular myocytes were evoked during 300-ms depolarizing voltage steps. B: Voltage relationship (I-V curves) in control and HFD mice. C: I peak at +70 mV in control and HFD mice. D: Representative I to recorded from ventricular myocytes of control (black) and HFD (red) mice. E: Voltage relationship (I-V curves) in the two groups. F: I to at +70 mV in the two groups. G, H and I: Steady-state activation (SSA), steady-state inactivation (SSI), and recovery from inactivation (RFI) curves of I to . J: Voltage relationship (I-V curves) of I K,slow in the two groups. K: I K,slow at +70 mV in the two groups. L: Analyzed fast (lower series) and slow (upper series) inactivation time constants (τ values) from currents. M: Representative Western blots of K V 4.2, KChIP2 and K V 1.5. N: Quantification of K V 4.2. O: Quantification of KChIP2. P: Quantification of K V 1.5. for A-L, n = 8 cells; three or four hearts per group. for M-P, n = 4 animals per group. * p <0.05, ** p <0.01.

    Journal: PLOS ONE

    Article Title: Obesity-induced activation of NADPH oxidase 2 prolongs cardiac repolarization via inhibiting K + currents

    doi: 10.1371/journal.pone.0316701

    Figure Lengend Snippet: A: Outward K + currents recorded from control (black) and HFD (red) mouse ventricular myocytes were evoked during 300-ms depolarizing voltage steps. B: Voltage relationship (I-V curves) in control and HFD mice. C: I peak at +70 mV in control and HFD mice. D: Representative I to recorded from ventricular myocytes of control (black) and HFD (red) mice. E: Voltage relationship (I-V curves) in the two groups. F: I to at +70 mV in the two groups. G, H and I: Steady-state activation (SSA), steady-state inactivation (SSI), and recovery from inactivation (RFI) curves of I to . J: Voltage relationship (I-V curves) of I K,slow in the two groups. K: I K,slow at +70 mV in the two groups. L: Analyzed fast (lower series) and slow (upper series) inactivation time constants (τ values) from currents. M: Representative Western blots of K V 4.2, KChIP2 and K V 1.5. N: Quantification of K V 4.2. O: Quantification of KChIP2. P: Quantification of K V 1.5. for A-L, n = 8 cells; three or four hearts per group. for M-P, n = 4 animals per group. * p <0.05, ** p <0.01.

    Article Snippet: Anti-K V 4.2 (APC-023), anti-KChIP2 (APC-142), anti-K ir 2.1 (APC-026), and anti-K V 1.5 (APC-004, Alomone); anti-Nox2 (Proteintech); and anti-tubulin (Immunoway) were used.

    Techniques: Control, Activation Assay, Western Blot