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rabbit  (Alomone Labs)


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    Alomone Labs rabbit
    Rabbit, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 96/100, based on 150 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/apc-035/pmc12410862-104-20-23?v=Alomone+Labs
    Average 96 stars, based on 150 article reviews
    rabbit - by Bioz Stars, 2026-07
    96/100 stars

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    A: Animal genotype and experimental timeline. B: Evaluation of auditory brainstem response between genotypes. There was a significant main effect of control vs. cKO (F (1, 3) = 20.21, p = 0.0205, peta2 [95%CI] = 0.87 [0.05 – 0.96]). Multiple comparison showed Adjusted p value =0.0045 at 8KHz, adjusted p value = 0.0045 at 16 KHz and, adjusted p value =0.0146 at 32 KHz (N=3; N=2). C: Graph of the endocochlear potential recorded between genotypes. To assess statistical significance between control and conditional knockout, Student’s t -tests were conducted to calculate p values. Pax3CreER-Kir4.1 fl/+ vs. Pax3CreER-Kir4.1 fl/fl , p value = 0.0034 (N=4; N=2). Immunostaining for evaluation of Kir 4.1 expression in the inner ear of WT (D) and conditional knockout (cKO) (E). Bracket for organ of Corti, arrows for Kir 4.1 positive melanocytes, stars for Kir 4.1 negative cells in the intermediate cell layer of the stria vascularis. RM: Reissner’s membrane, SGN: spiral ganglion neurons, TAM: Tamoxifen induction.
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    A: Animal genotype and experimental timeline. B: Evaluation of auditory brainstem response between genotypes. There was a significant main effect of control vs. cKO (F (1, 3) = 20.21, p = 0.0205, peta2 [95%CI] = 0.87 [0.05 – 0.96]). Multiple comparison showed Adjusted p value =0.0045 at 8KHz, adjusted p value = 0.0045 at 16 KHz and, adjusted p value =0.0146 at 32 KHz (N=3; N=2). C: Graph of the endocochlear potential recorded between genotypes. To assess statistical significance between control and conditional knockout, Student’s t -tests were conducted to calculate p values. Pax3CreER-Kir4.1 fl/+ vs. Pax3CreER-Kir4.1 fl/fl , p value = 0.0034 (N=4; N=2). Immunostaining for evaluation of Kir 4.1 expression in the inner ear of WT (D) and conditional knockout (cKO) (E). Bracket for organ of Corti, arrows for Kir 4.1 positive melanocytes, stars for Kir 4.1 negative cells in the intermediate cell layer of the stria vascularis. RM: Reissner’s membrane, SGN: spiral ganglion neurons, TAM: Tamoxifen induction.

    Journal: Developmental biology

    Article Title: Targeting the melanocytes of the inner ear: A comparison of different CreER lines

    doi: 10.1016/j.ydbio.2025.12.009

    Figure Lengend Snippet: A: Animal genotype and experimental timeline. B: Evaluation of auditory brainstem response between genotypes. There was a significant main effect of control vs. cKO (F (1, 3) = 20.21, p = 0.0205, peta2 [95%CI] = 0.87 [0.05 – 0.96]). Multiple comparison showed Adjusted p value =0.0045 at 8KHz, adjusted p value = 0.0045 at 16 KHz and, adjusted p value =0.0146 at 32 KHz (N=3; N=2). C: Graph of the endocochlear potential recorded between genotypes. To assess statistical significance between control and conditional knockout, Student’s t -tests were conducted to calculate p values. Pax3CreER-Kir4.1 fl/+ vs. Pax3CreER-Kir4.1 fl/fl , p value = 0.0034 (N=4; N=2). Immunostaining for evaluation of Kir 4.1 expression in the inner ear of WT (D) and conditional knockout (cKO) (E). Bracket for organ of Corti, arrows for Kir 4.1 positive melanocytes, stars for Kir 4.1 negative cells in the intermediate cell layer of the stria vascularis. RM: Reissner’s membrane, SGN: spiral ganglion neurons, TAM: Tamoxifen induction.

    Article Snippet: The slides were washed with 1x PBS and immunolabelled the intermediate cells with primary antibody CD44 (Rat MA4405, Fisher Scientific, 1:250) or KIR 4.1 (Rabbit APC-035, Alomone; 1:100) diluted in 5% serum/PBS overnight at 4°C.

    Techniques: Expressing, Control, Comparison, Knock-Out, Immunostaining, Membrane