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Journal: Scientific Reports
Article Title: Investigating the effects of stereotactic body radiation therapy on pancreatic tumor hypoxia and microvasculature in an orthotopic mouse model using intravital fluorescence microscopy
doi: 10.1038/s41598-024-82757-1
Figure Lengend Snippet: 5 × 8 Gy SBRT decreases pancreatic tumor hypoxia. ( a ) Intravital fluorescence microscopy of 5xHRE/GFP-expressing BxPC3 tumor cells show a significant decrease in the GFP mean fluorescence intensity (MFI) 1 day post-SBRT. ( b ) Representative images and ( c ) quantification of CA9 staining (brown) in ex vivo BxPC3 tumor tissue sections show a significant decrease in tumor cell hypoxia at both 1 and 14 days post-SBRT, compared to non-irradiated control mice. Tissue sections are counterstained with hematoxylin (blue). Scale bar = 200 μm. n = 7 mice per group. *p < 0.05.
Article Snippet: ,
Techniques: Fluorescence, Microscopy, Expressing, Staining, Ex Vivo, Irradiation, Control
Journal: Scientific Reports
Article Title: Investigating the effects of stereotactic body radiation therapy on pancreatic tumor hypoxia and microvasculature in an orthotopic mouse model using intravital fluorescence microscopy
doi: 10.1038/s41598-024-82757-1
Figure Lengend Snippet: Antibodies and dilutions used in the study.
Article Snippet: ,
Techniques: