anti clc 2  (Alomone Labs)

Journal: Frontiers in Neuroscience

Article Title: Olfactory neuronal cells as a promising tool to realize the “druggable genome” approach for drug discovery in neuropsychiatric disorders

doi: 10.3389/fnins.2022.1081124

Figure Lengend Snippet: Differences in gene expression levels between patients and HCs.

Article Snippet: Membranes were incubated with an antibody against CLCN2 (Alomone Labs, ACL-002) (1:200 dilution) or with an antibody against GAPDH (Santa Cruz Biotech, sc-32233) (1:4000 dilution) overnight at 4°C, washed, and incubated in a horseradish peroxidase-conjugated secondary antibody (GE Healthcare, NA934V for CLCN2; NA931V for GAPDH) (1:5000 dilution) for 1 h at room temperature.

Techniques: Expressing

Journal: Frontiers in Neuroscience

Article Title: Olfactory neuronal cells as a promising tool to realize the “druggable genome” approach for drug discovery in neuropsychiatric disorders

doi: 10.3389/fnins.2022.1081124

Figure Lengend Snippet: Association between verbal memory and executive function with gene expression levels.

Article Snippet: Membranes were incubated with an antibody against CLCN2 (Alomone Labs, ACL-002) (1:200 dilution) or with an antibody against GAPDH (Santa Cruz Biotech, sc-32233) (1:4000 dilution) overnight at 4°C, washed, and incubated in a horseradish peroxidase-conjugated secondary antibody (GE Healthcare, NA934V for CLCN2; NA931V for GAPDH) (1:5000 dilution) for 1 h at room temperature.

Techniques: Expressing

Journal: Frontiers in Neuroscience

Article Title: Olfactory neuronal cells as a promising tool to realize the “druggable genome” approach for drug discovery in neuropsychiatric disorders

doi: 10.3389/fnins.2022.1081124

Figure Lengend Snippet: Bar plot of T values from the linear regression analysis between expression levels of the CLCN2 gene and each neuropsychological domain. We tested the association between CLCN2 expressional levels and all neuropsychological domains in patients. A significant correlation was observed for verbal memory. The red dashed line represents the significant cut-off ( p < 0.05).

Article Snippet: Membranes were incubated with an antibody against CLCN2 (Alomone Labs, ACL-002) (1:200 dilution) or with an antibody against GAPDH (Santa Cruz Biotech, sc-32233) (1:4000 dilution) overnight at 4°C, washed, and incubated in a horseradish peroxidase-conjugated secondary antibody (GE Healthcare, NA934V for CLCN2; NA931V for GAPDH) (1:5000 dilution) for 1 h at room temperature.

Techniques: Expressing