Ifnγ, supplied by Kingfisher Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1) Product Images from "Placenta-derived multipotent mesenchymal stromal cells: a promising potential cell-based therapy for canine inflammatory brain disease"
Article Title: Placenta-derived multipotent mesenchymal stromal cells: a promising potential cell-based therapy for canine inflammatory brain disease
Journal: Stem Cell Research & Therapy
Figure Legend Snippet: Direct stimulation of canine ASCs and PMSCs leads to production of IDO and PGE 2 . Canine adipose-derived MSCs ( ASCs ) and placenta-derived MSCs ( PMSCs ) secrete increased levels of indoleamine 2,3 dioxygenase (IDO) activity and prostaglandin E 2 (PGE 2 ) in response to direct stimulation using recombinant interferon gamma (IFNγ) and tumor necrosis factor alpha (TNFα ) . a IDO activity is directly proportional to the conversion of tryptophan to N -formyl kynurenine. ASCs and PMSCs increase IDO activity in response to dual stimulation with IFNγ and TNFα. IFNγ is the main contributor to the production of IDO. IFNγ- and TNFα-stimulated ASCs promote significantly higher levels of IDO activity as compared to PMSCs. b Canine ASCs and PMSCs produce comparable levels of prostaglandin E 2 (PGE 2 ) in response to dual stimulation with IFNγ and TNFα. TNFα is the major contributor to MSC-mediated PGE 2 production. Data presented as mean and standard error. * p
Techniques Used: Derivative Assay, Activity Assay, Recombinant