ifnγ  (Kingfisher Biotech)


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    Structured Review

    Kingfisher Biotech ifnγ
    Direct stimulation of canine ASCs and PMSCs leads to production of IDO and PGE 2 . Canine adipose-derived MSCs ( ASCs ) and placenta-derived MSCs ( PMSCs ) secrete increased levels of indoleamine 2,3 dioxygenase (IDO) activity and prostaglandin E 2 (PGE 2 ) in response to direct stimulation using recombinant interferon gamma <t>(IFNγ)</t> and tumor necrosis factor alpha (TNFα ) . a IDO activity is directly proportional to the conversion of tryptophan to N -formyl kynurenine. ASCs and PMSCs increase IDO activity in response to dual stimulation with IFNγ and TNFα. IFNγ is the main contributor to the production of IDO. IFNγ- and TNFα-stimulated ASCs promote significantly higher levels of IDO activity as compared to PMSCs. b Canine ASCs and PMSCs produce comparable levels of prostaglandin E 2 (PGE 2 ) in response to dual stimulation with IFNγ and TNFα. TNFα is the major contributor to MSC-mediated PGE 2 production. Data presented as mean and standard error. * p
    Ifnγ, supplied by Kingfisher Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ifnγ/product/Kingfisher Biotech
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    ifnγ - by Bioz Stars, 2022-05
    93/100 stars

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    1) Product Images from "Placenta-derived multipotent mesenchymal stromal cells: a promising potential cell-based therapy for canine inflammatory brain disease"

    Article Title: Placenta-derived multipotent mesenchymal stromal cells: a promising potential cell-based therapy for canine inflammatory brain disease

    Journal: Stem Cell Research & Therapy

    doi: 10.1186/s13287-020-01799-0

    Direct stimulation of canine ASCs and PMSCs leads to production of IDO and PGE 2 . Canine adipose-derived MSCs ( ASCs ) and placenta-derived MSCs ( PMSCs ) secrete increased levels of indoleamine 2,3 dioxygenase (IDO) activity and prostaglandin E 2 (PGE 2 ) in response to direct stimulation using recombinant interferon gamma (IFNγ) and tumor necrosis factor alpha (TNFα ) . a IDO activity is directly proportional to the conversion of tryptophan to N -formyl kynurenine. ASCs and PMSCs increase IDO activity in response to dual stimulation with IFNγ and TNFα. IFNγ is the main contributor to the production of IDO. IFNγ- and TNFα-stimulated ASCs promote significantly higher levels of IDO activity as compared to PMSCs. b Canine ASCs and PMSCs produce comparable levels of prostaglandin E 2 (PGE 2 ) in response to dual stimulation with IFNγ and TNFα. TNFα is the major contributor to MSC-mediated PGE 2 production. Data presented as mean and standard error. * p
    Figure Legend Snippet: Direct stimulation of canine ASCs and PMSCs leads to production of IDO and PGE 2 . Canine adipose-derived MSCs ( ASCs ) and placenta-derived MSCs ( PMSCs ) secrete increased levels of indoleamine 2,3 dioxygenase (IDO) activity and prostaglandin E 2 (PGE 2 ) in response to direct stimulation using recombinant interferon gamma (IFNγ) and tumor necrosis factor alpha (TNFα ) . a IDO activity is directly proportional to the conversion of tryptophan to N -formyl kynurenine. ASCs and PMSCs increase IDO activity in response to dual stimulation with IFNγ and TNFα. IFNγ is the main contributor to the production of IDO. IFNγ- and TNFα-stimulated ASCs promote significantly higher levels of IDO activity as compared to PMSCs. b Canine ASCs and PMSCs produce comparable levels of prostaglandin E 2 (PGE 2 ) in response to dual stimulation with IFNγ and TNFα. TNFα is the major contributor to MSC-mediated PGE 2 production. Data presented as mean and standard error. * p

    Techniques Used: Derivative Assay, Activity Assay, Recombinant

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  • 93
    Kingfisher Biotech ifnγ
    Direct stimulation of canine ASCs and PMSCs leads to production of IDO and PGE 2 . Canine adipose-derived MSCs ( ASCs ) and placenta-derived MSCs ( PMSCs ) secrete increased levels of indoleamine 2,3 dioxygenase (IDO) activity and prostaglandin E 2 (PGE 2 ) in response to direct stimulation using recombinant interferon gamma <t>(IFNγ)</t> and tumor necrosis factor alpha (TNFα ) . a IDO activity is directly proportional to the conversion of tryptophan to N -formyl kynurenine. ASCs and PMSCs increase IDO activity in response to dual stimulation with IFNγ and TNFα. IFNγ is the main contributor to the production of IDO. IFNγ- and TNFα-stimulated ASCs promote significantly higher levels of IDO activity as compared to PMSCs. b Canine ASCs and PMSCs produce comparable levels of prostaglandin E 2 (PGE 2 ) in response to dual stimulation with IFNγ and TNFα. TNFα is the major contributor to MSC-mediated PGE 2 production. Data presented as mean and standard error. * p
    Ifnγ, supplied by Kingfisher Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ifnγ/product/Kingfisher Biotech
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    ifnγ - by Bioz Stars, 2022-05
    93/100 stars
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    Direct stimulation of canine ASCs and PMSCs leads to production of IDO and PGE 2 . Canine adipose-derived MSCs ( ASCs ) and placenta-derived MSCs ( PMSCs ) secrete increased levels of indoleamine 2,3 dioxygenase (IDO) activity and prostaglandin E 2 (PGE 2 ) in response to direct stimulation using recombinant interferon gamma (IFNγ) and tumor necrosis factor alpha (TNFα ) . a IDO activity is directly proportional to the conversion of tryptophan to N -formyl kynurenine. ASCs and PMSCs increase IDO activity in response to dual stimulation with IFNγ and TNFα. IFNγ is the main contributor to the production of IDO. IFNγ- and TNFα-stimulated ASCs promote significantly higher levels of IDO activity as compared to PMSCs. b Canine ASCs and PMSCs produce comparable levels of prostaglandin E 2 (PGE 2 ) in response to dual stimulation with IFNγ and TNFα. TNFα is the major contributor to MSC-mediated PGE 2 production. Data presented as mean and standard error. * p

    Journal: Stem Cell Research & Therapy

    Article Title: Placenta-derived multipotent mesenchymal stromal cells: a promising potential cell-based therapy for canine inflammatory brain disease

    doi: 10.1186/s13287-020-01799-0

    Figure Lengend Snippet: Direct stimulation of canine ASCs and PMSCs leads to production of IDO and PGE 2 . Canine adipose-derived MSCs ( ASCs ) and placenta-derived MSCs ( PMSCs ) secrete increased levels of indoleamine 2,3 dioxygenase (IDO) activity and prostaglandin E 2 (PGE 2 ) in response to direct stimulation using recombinant interferon gamma (IFNγ) and tumor necrosis factor alpha (TNFα ) . a IDO activity is directly proportional to the conversion of tryptophan to N -formyl kynurenine. ASCs and PMSCs increase IDO activity in response to dual stimulation with IFNγ and TNFα. IFNγ is the main contributor to the production of IDO. IFNγ- and TNFα-stimulated ASCs promote significantly higher levels of IDO activity as compared to PMSCs. b Canine ASCs and PMSCs produce comparable levels of prostaglandin E 2 (PGE 2 ) in response to dual stimulation with IFNγ and TNFα. TNFα is the major contributor to MSC-mediated PGE 2 production. Data presented as mean and standard error. * p

    Article Snippet: At plating, MSC was stimulated with IFNγ (50 ng/mL; canine recombinant IFNγ, Kingfisher, St. Paul, MN) or TNFα (50 ng/mL; canine recombinant TNFα, Kingfisher) or a dual stimulation with both IFNγ (50 ng/mL, Kingfisher) and TNFα (50 ng/mL, Kingfisher).

    Techniques: Derivative Assay, Activity Assay, Recombinant

    Relative gene expression after 96 h following AdMSC stimulation with interferon-gamma (IFN-γ). a Relative expression of BDNF, b GDNF, c HGF, and d IL-10. The samples were tested with two reference genes, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and hypoxanthine phosphoribosyl transferase (HPRT). Data are represented as mean ± SEM. p

    Journal: Stem Cell Research & Therapy

    Article Title: 3D-printed nerve guidance conduits multi-functionalized with canine multipotent mesenchymal stromal cells promote neuroregeneration after sciatic nerve injury in rats

    doi: 10.1186/s13287-021-02315-8

    Figure Lengend Snippet: Relative gene expression after 96 h following AdMSC stimulation with interferon-gamma (IFN-γ). a Relative expression of BDNF, b GDNF, c HGF, and d IL-10. The samples were tested with two reference genes, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and hypoxanthine phosphoribosyl transferase (HPRT). Data are represented as mean ± SEM. p

    Article Snippet: Subsequently, cells were stimulated with 0.75 mL basal medium containing IFN-γ (50 ng/mL, IFN- γ canine recombinant; Kingfisher Biotech, Saint Paul, USA) for 96 h. At this point, the cells were collected using TRIzol reagent (Invitrogen, São Paulo, Brazil) and stored at − 80 °C for RNA extraction and analysis of gene expression.

    Techniques: Expressing