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Three-dimensional binding mode of compound 9 (green) at the binding interface between the SARS-CoV-2 S-RBD (red) and human ACE2 (blue).

Journal: Life

Article Title: 1,2,3-Triazole-Benzofused Molecular Conjugates as Potential Antiviral Agents against SARS-CoV-2 Virus Variants

doi: 10.3390/life12091341

Figure Lengend Snippet: Three-dimensional binding mode of compound 9 (green) at the binding interface between the SARS-CoV-2 S-RBD (red) and human ACE2 (blue).

Article Snippet: SARS-CoV-2 assay kit (SARS-CoV-2 Assay Kit, Biosource, Muskego, WI, USA) and the Omicron variant Spike RBD inhibitor screening kits (B.1.1.529 BA.1, Omicron Variant Assay Kit, BPS Bioscience, San Diego, CA, USA) were used to evaluate the anti-SARS-CoV-2 activity in vitro.

Techniques: Binding Assay