Review





Similar Products

25 hydroxycholesterol 3 sulfate  (Avanti Polar)
92
Avanti Polar 25 hydroxycholesterol 3 sulfate
Synthesis of 22( S <t>)-Hydroxycholesterol-3-sulfate</t> sodium salt (PFM037) a . a Reagents and conditions: (a) isoamyl bromide, Mg, 0 °C to rt, 5 h; (b) i. Ac 2 O, 4-DMAP, CH 2 Cl 2 , pyridine, rt, 20 h; ii. p TsOH, dioxane/H 2 O, 80 °C, 1 h; (c) i. SO 3 -pyridine complex, pyridine, rt, 4 h; ii. 1.25 M NaOH in MeOH, reflux for 1 h, then rt overnight.
25 Hydroxycholesterol 3 Sulfate, supplied by Avanti Polar, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/25 hydroxycholesterol 3 sulfate/product/Avanti Polar
Average 92 stars, based on 1 article reviews
25 hydroxycholesterol 3 sulfate - by Bioz Stars, 2025-11
92/100 stars
  Buy from Supplier
hydroxycholesterol 3 sulfate  (Avanti Polar)
92
Avanti Polar hydroxycholesterol 3 sulfate
Synthesis of 22( S <t>)-Hydroxycholesterol-3-sulfate</t> sodium salt (PFM037) a . a Reagents and conditions: (a) isoamyl bromide, Mg, 0 °C to rt, 5 h; (b) i. Ac 2 O, 4-DMAP, CH 2 Cl 2 , pyridine, rt, 20 h; ii. p TsOH, dioxane/H 2 O, 80 °C, 1 h; (c) i. SO 3 -pyridine complex, pyridine, rt, 4 h; ii. 1.25 M NaOH in MeOH, reflux for 1 h, then rt overnight.
Hydroxycholesterol 3 Sulfate, supplied by Avanti Polar, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hydroxycholesterol 3 sulfate/product/Avanti Polar
Average 92 stars, based on 1 article reviews
hydroxycholesterol 3 sulfate - by Bioz Stars, 2025-11
92/100 stars
  Buy from Supplier
25 hydroxycholesterol 3 sulfate  (TargetMol)
91
TargetMol 25 hydroxycholesterol 3 sulfate
Effect of squalene and <t>25-hydroxycholesterol-3-sulfate</t> (25HC3S) on Caco-2 cells. ( A ) Schematic illustration for effects of cholesterol precursor and inhibitors on cancer cells. ( B ) Cell viability of cancer cells treated with different concentrations of squalene at different times (24 h, 48 h, 72 h, and 96 h). ( C ) Cell viability of cancer cells treated with different concentrations of 25HC3S at 48 h. ( D ) Expression levels of targeted genes of cholesterol biosynthesis pathway. Data are presented as Mean ± Standard Error (three biological replicates per group). Statistical significance by Student’s t test; *, p < 0.05; **, p < 0.01.
25 Hydroxycholesterol 3 Sulfate, supplied by TargetMol, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/25 hydroxycholesterol 3 sulfate/product/TargetMol
Average 91 stars, based on 1 article reviews
25 hydroxycholesterol 3 sulfate - by Bioz Stars, 2025-11
91/100 stars
  Buy from Supplier
hydroxycholesterol 3 sulfate 25 hcs  (Avanti Polar)
92
Avanti Polar hydroxycholesterol 3 sulfate 25 hcs
Effect of squalene and <t>25-hydroxycholesterol-3-sulfate</t> (25HC3S) on Caco-2 cells. ( A ) Schematic illustration for effects of cholesterol precursor and inhibitors on cancer cells. ( B ) Cell viability of cancer cells treated with different concentrations of squalene at different times (24 h, 48 h, 72 h, and 96 h). ( C ) Cell viability of cancer cells treated with different concentrations of 25HC3S at 48 h. ( D ) Expression levels of targeted genes of cholesterol biosynthesis pathway. Data are presented as Mean ± Standard Error (three biological replicates per group). Statistical significance by Student’s t test; *, p < 0.05; **, p < 0.01.
Hydroxycholesterol 3 Sulfate 25 Hcs, supplied by Avanti Polar, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hydroxycholesterol 3 sulfate 25 hcs/product/Avanti Polar
Average 92 stars, based on 1 article reviews
hydroxycholesterol 3 sulfate 25 hcs - by Bioz Stars, 2025-11
92/100 stars
  Buy from Supplier
25 hydroxycholesterol sulfate sodium salt  (Avanti Polar)
95
Avanti Polar 25 hydroxycholesterol sulfate sodium salt
Effect of squalene and <t>25-hydroxycholesterol-3-sulfate</t> (25HC3S) on Caco-2 cells. ( A ) Schematic illustration for effects of cholesterol precursor and inhibitors on cancer cells. ( B ) Cell viability of cancer cells treated with different concentrations of squalene at different times (24 h, 48 h, 72 h, and 96 h). ( C ) Cell viability of cancer cells treated with different concentrations of 25HC3S at 48 h. ( D ) Expression levels of targeted genes of cholesterol biosynthesis pathway. Data are presented as Mean ± Standard Error (three biological replicates per group). Statistical significance by Student’s t test; *, p < 0.05; **, p < 0.01.
25 Hydroxycholesterol Sulfate Sodium Salt, supplied by Avanti Polar, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/25 hydroxycholesterol sulfate sodium salt/product/Avanti Polar
Average 95 stars, based on 1 article reviews
25 hydroxycholesterol sulfate sodium salt - by Bioz Stars, 2025-11
95/100 stars
  Buy from Supplier
7α 25 26 26 26 27 27 27 2h7 hydroxycholesterol  (Avanti Polar)
93
Avanti Polar 7α 25 26 26 26 27 27 27 2h7 hydroxycholesterol
Effect of squalene and <t>25-hydroxycholesterol-3-sulfate</t> (25HC3S) on Caco-2 cells. ( A ) Schematic illustration for effects of cholesterol precursor and inhibitors on cancer cells. ( B ) Cell viability of cancer cells treated with different concentrations of squalene at different times (24 h, 48 h, 72 h, and 96 h). ( C ) Cell viability of cancer cells treated with different concentrations of 25HC3S at 48 h. ( D ) Expression levels of targeted genes of cholesterol biosynthesis pathway. Data are presented as Mean ± Standard Error (three biological replicates per group). Statistical significance by Student’s t test; *, p < 0.05; **, p < 0.01.
7α 25 26 26 26 27 27 27 2h7 Hydroxycholesterol, supplied by Avanti Polar, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/7α 25 26 26 26 27 27 27 2h7 hydroxycholesterol/product/Avanti Polar
Average 93 stars, based on 1 article reviews
7α 25 26 26 26 27 27 27 2h7 hydroxycholesterol - by Bioz Stars, 2025-11
93/100 stars
  Buy from Supplier
25-hydroxycholesterol-3-sulfate  (Avanti Polar)
92
Avanti Polar 25-hydroxycholesterol-3-sulfate
Effect of squalene and <t>25-hydroxycholesterol-3-sulfate</t> (25HC3S) on Caco-2 cells. ( A ) Schematic illustration for effects of cholesterol precursor and inhibitors on cancer cells. ( B ) Cell viability of cancer cells treated with different concentrations of squalene at different times (24 h, 48 h, 72 h, and 96 h). ( C ) Cell viability of cancer cells treated with different concentrations of 25HC3S at 48 h. ( D ) Expression levels of targeted genes of cholesterol biosynthesis pathway. Data are presented as Mean ± Standard Error (three biological replicates per group). Statistical significance by Student’s t test; *, p < 0.05; **, p < 0.01.
25 Hydroxycholesterol 3 Sulfate, supplied by Avanti Polar, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/25-hydroxycholesterol-3-sulfate/product/Avanti Polar
Average 92 stars, based on 1 article reviews
25-hydroxycholesterol-3-sulfate - by Bioz Stars, 2025-11
92/100 stars
  Buy from Supplier

Image Search Results


Synthesis of 22( S )-Hydroxycholesterol-3-sulfate sodium salt (PFM037) a . a Reagents and conditions: (a) isoamyl bromide, Mg, 0 °C to rt, 5 h; (b) i. Ac 2 O, 4-DMAP, CH 2 Cl 2 , pyridine, rt, 20 h; ii. p TsOH, dioxane/H 2 O, 80 °C, 1 h; (c) i. SO 3 -pyridine complex, pyridine, rt, 4 h; ii. 1.25 M NaOH in MeOH, reflux for 1 h, then rt overnight.

Journal: Cell Death & Disease

Article Title: Harnessing the reverse cholesterol transport pathway to favor differentiation of monocyte-derived APCs and antitumor responses

doi: 10.1038/s41419-023-05620-7

Figure Lengend Snippet: Synthesis of 22( S )-Hydroxycholesterol-3-sulfate sodium salt (PFM037) a . a Reagents and conditions: (a) isoamyl bromide, Mg, 0 °C to rt, 5 h; (b) i. Ac 2 O, 4-DMAP, CH 2 Cl 2 , pyridine, rt, 20 h; ii. p TsOH, dioxane/H 2 O, 80 °C, 1 h; (c) i. SO 3 -pyridine complex, pyridine, rt, 4 h; ii. 1.25 M NaOH in MeOH, reflux for 1 h, then rt overnight.

Article Snippet: 25-Hydroxycholesterol-3-sulfate (25-HC-3S) was from Avanti Polar Lipids.

Techniques: Reflux

Effect of squalene and 25-hydroxycholesterol-3-sulfate (25HC3S) on Caco-2 cells. ( A ) Schematic illustration for effects of cholesterol precursor and inhibitors on cancer cells. ( B ) Cell viability of cancer cells treated with different concentrations of squalene at different times (24 h, 48 h, 72 h, and 96 h). ( C ) Cell viability of cancer cells treated with different concentrations of 25HC3S at 48 h. ( D ) Expression levels of targeted genes of cholesterol biosynthesis pathway. Data are presented as Mean ± Standard Error (three biological replicates per group). Statistical significance by Student’s t test; *, p < 0.05; **, p < 0.01.

Journal: Biomolecules

Article Title: Bioinformatics Analysis of LGR4 in Colon Adenocarcinoma as Potential Diagnostic Biomarker, Therapeutic Target and Promoting Immune Cell Infiltration

doi: 10.3390/biom12081081

Figure Lengend Snippet: Effect of squalene and 25-hydroxycholesterol-3-sulfate (25HC3S) on Caco-2 cells. ( A ) Schematic illustration for effects of cholesterol precursor and inhibitors on cancer cells. ( B ) Cell viability of cancer cells treated with different concentrations of squalene at different times (24 h, 48 h, 72 h, and 96 h). ( C ) Cell viability of cancer cells treated with different concentrations of 25HC3S at 48 h. ( D ) Expression levels of targeted genes of cholesterol biosynthesis pathway. Data are presented as Mean ± Standard Error (three biological replicates per group). Statistical significance by Student’s t test; *, p < 0.05; **, p < 0.01.

Article Snippet: Squalene (J&K, Shanghai, China) and 25-hydroxycholesterol-3-sulfate (TargetMol, Shangahi, China) were suspended in DMEM, and then Caco-2 cells were incubated with drugs following the given concentration.

Techniques: Expressing