cbr1 (Santa Cruz Biotechnology)
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Structured Review
Santa Cruz Biotechnology
cbr1
Cbr1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 16 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/100518-1/Carbonyl+reductase+1+Antibody/pmc10861747-49-12-22
Average 93 stars, based on 16 article reviews
Cbr1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 16 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/100518-1/Carbonyl+reductase+1+Antibody/pmc10861747-49-12-22
Average 93 stars, based on 16 article reviews
cbr1 - by Bioz Stars,
2026-09
93/100 stars
Images
1) Product Images from "In vitro evaluation of the reductive carbonyl idarubicin metabolism to evaluate inhibitors of the formation of cardiotoxic idarubicinol via carbonyl and aldo–keto reductases"
Article Title: In vitro evaluation of the reductive carbonyl idarubicin metabolism to evaluate inhibitors of the formation of cardiotoxic idarubicinol via carbonyl and aldo–keto reductases
Journal: Archives of Toxicology
doi: 10.1007/s00204-023-03661-7
Figure Legend Snippet: Western blot of the AKR1B1, AKR1A1, AKR1C3, CBR1, and CBR3 in HepG2, MCF-7, and HEK293 cells. β-actin served as a loading control. Depicted is one blot of a series of three for each protein investigated
Techniques Used: Western Blot, Control
Figure Legend Snippet: Inhibition of idarubicinol formation by different inhibitors in HEK293, HepG2, and MCF-7 cells
Techniques Used: Inhibition
Figure Legend Snippet: Expression of the mRNA of the five reductases in human liver samples and HepG2 cells. mRNA expression of AKR1A1, AKR1B1, AKR1C3, CBR1 , and CBR3 was quantified in 7 human liver samples and HepG2 cells via real-time RT-PCR and normalized to the expression of the two housekeeping genes HUPO and RPL13 . Each data point for the liver samples represents the mean of a technical duplicate and the data for the HepG2 cells represent the mean ± S.E.M. for n = 7
Techniques Used: Expressing, Quantitative RT-PCR
Related Articles
Bioprocessing:Article Title: In vitro evaluation of the reductive carbonyl idarubicin metabolism to evaluate inhibitors of the formation of cardiotoxic idarubicinol via carbonyl and aldo-keto reductases. Article Snippet: The RevertAidTM H Minus First Strand cDNA Synthesis Kit, the Absolute QPCR SYBR Green Mix, the PierceTM BCA Protein Assay Kit, the Pierce ECL Western Blotting Substrate, the secondary HRP-conjugated antirabbit antibody, 2’-hydroxy-flavanone (2-OH-flavanone), and the RIPA buffer were purchased from Thermo Fisher Scientific (Waltham, MA, USA). .. The mouse monoclonal antibodies against β-actin (sc-47778), AKR1B1 (aldose reductase (H-6, sc-166918)), Article Title: In vitro evaluation of the reductive carbonyl idarubicin metabolism to evaluate inhibitors of the formation of cardiotoxic idarubicinol via carbonyl and aldo–keto reductases Article Snippet: The RevertAidTM H Minus First Strand cDNA Synthesis Kit, the Absolute QPCR SYBR Green Mix, the PierceTM BCA Protein Assay Kit, the Pierce ECL Western Blotting Substrate, the secondary HRP-conjugated anti-rabbit antibody, 2’-hydroxy-flavanone (2-OH-flavanone), and the RIPA buffer were purchased from Thermo Fisher Scientific (Waltham, MA, USA). .. The mouse monoclonal antibodies against β-actin (sc-47778), AKR1B1 (aldose reductase (H-6, sc-166918)), other:Article Title: Effects of cellular differentiation in human primary bronchial epithelial cells: Metabolism of 4-(methylnitrosamine)-1-(3-pyridyl)-1-butanone Article Snippet: All analyses were conducted using GraphPad Prism (La Jolla, CA). |
