Mitomycin C cell culture reagent
Life Sciences Biochemicals Antibiotics
Generate mitotically inactive feeder cells
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1) Product Images from "Distinct cellular phenotype linked to defective DNA interstrand crosslink repair and homologous recombination"
Article Title: Distinct cellular phenotype linked to defective DNA interstrand crosslink repair and homologous recombination
Journal: Molecular Medicine Reports
Figure Legend Snippet: Kinetics of Rad51 foci formation in V79B and CL-V8B cells after (A) BLM and (B) MMC exposure. V-C8 defective in Brca2 / Fancd1 (HR and Fanconi anemia pathway) represent control cell line with Rad51 foci impairment. Data represent mean values from at least three independent experiments. Error bars represent standard error. BLM, bleomycin; MMC, mitomycin C; HR, homologous recombination.
Techniques Used: Homologous Recombination
Figure Legend Snippet: Clonogenic survival of CL-V8B and the parental cell line V79B following exposure to (A) MMC, (B) CDDP, (C) UVC radiation, (D) hydrogen peroxide, (E) CPT, (F) HU, (G) BLM, (H) 6-tG, (I) poly (adenosine diphosphate-ribose) polymerase inhibitor KU0058948. Data are presented as the mean values from at least three independent experiments. Error bars represent standard error. MMC, mitomycin C; CDDP, cisplatin; CPT, camptothecin; HU, hydroxyurea; BLM, bleomycin; 6-tG, 6-tioguanine.
Techniques Used: Cycling Probe Technology