dull foveal reflex faint perifoveal hyperfluorescent ring presence  (Cell Signaling Technology Inc)


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    Structured Review

    Cell Signaling Technology Inc dull foveal reflex faint perifoveal hyperfluorescent ring presence
    Retinal Findings in the Cases at the Most Recent Visit
    Dull Foveal Reflex Faint Perifoveal Hyperfluorescent Ring Presence, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dull foveal reflex faint perifoveal hyperfluorescent ring presence/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    dull foveal reflex faint perifoveal hyperfluorescent ring presence - by Bioz Stars, 2023-02
    86/100 stars

    Images

    1) Product Images from "Phenotypic Characteristics Including In Vivo Cone Photoreceptor Mosaic in KCNV2- Related "Cone Dystrophy with Supernormal Rod Electroretinogram""

    Article Title: Phenotypic Characteristics Including In Vivo Cone Photoreceptor Mosaic in KCNV2- Related "Cone Dystrophy with Supernormal Rod Electroretinogram"

    Journal: Investigative ophthalmology & visual science

    doi: 10.1167/iovs.12-10971

    Retinal Findings in the Cases at the Most Recent Visit
    Figure Legend Snippet: Retinal Findings in the Cases at the Most Recent Visit

    Techniques Used: Tomography

    Fundus photographs (A–G), FAF images (H–N), and SD-OCT images (O–V) from one eye of all seven cases. Each horizontal panel represents corresponding fundus photo and FAF and SD-OCT images from the same eye of each individual case. Fundus photos show minimal retinal pigment epithelial changes at the macula in cases 2, 3, 6, and 7 (B, C, F, G). White boxes in fundus images represent 2° by 2° retinal locations from where AOSLO images were obtained. FAF showed a perifoveal ring of hyperfluorescence in five cases (white arrows in H, J–L, N). The SD-OCT (O–V) images show disruption of the IS-OS junction (asterisk) or optical gap (cross) at the fovea. (P) Foveal and (Q) perifoveal SD-OCT scans from the left eye of case 2 within the 2° by 2° square in Figure 1B, and demonstrate reasonable preservation of the IS-OS junction 250 μm inferior to fovea (Q) compared to the fovea (P). All the retinal layers are marked: ELM, external limitingmembrane; OPL, outer plexiform layer; IPL, inner plexiform layer; INL, inner nuclear layer; OS, photoreceptor outer segment; IS-OS, inner segment-outer segment junction. Photoreceptors within the white box on SD-OCT fall within the region scanned by AOSLO.
    Figure Legend Snippet: Fundus photographs (A–G), FAF images (H–N), and SD-OCT images (O–V) from one eye of all seven cases. Each horizontal panel represents corresponding fundus photo and FAF and SD-OCT images from the same eye of each individual case. Fundus photos show minimal retinal pigment epithelial changes at the macula in cases 2, 3, 6, and 7 (B, C, F, G). White boxes in fundus images represent 2° by 2° retinal locations from where AOSLO images were obtained. FAF showed a perifoveal ring of hyperfluorescence in five cases (white arrows in H, J–L, N). The SD-OCT (O–V) images show disruption of the IS-OS junction (asterisk) or optical gap (cross) at the fovea. (P) Foveal and (Q) perifoveal SD-OCT scans from the left eye of case 2 within the 2° by 2° square in Figure 1B, and demonstrate reasonable preservation of the IS-OS junction 250 μm inferior to fovea (Q) compared to the fovea (P). All the retinal layers are marked: ELM, external limitingmembrane; OPL, outer plexiform layer; IPL, inner plexiform layer; INL, inner nuclear layer; OS, photoreceptor outer segment; IS-OS, inner segment-outer segment junction. Photoreceptors within the white box on SD-OCT fall within the region scanned by AOSLO.

    Techniques Used: Preserving

    (A–G) Macular cone photoreceptor morphology in six cases. The AOSLO images are shown for subsections of 2° by 2° fields, centered on the horizontal meridian, below a 2° horizontal section of SD-OCT that overlaps the region scanned by the AOSLO. The AOSLO images from similar eccentricities in a control subject are also provided (H–J). Each AO image is cropped from the original 2° by 2° frames to include regions in most focus. Horizontal bars on each of the AOSLO and SD-OCT images represent 0.4°. The approximate horizontal center of each AOSLO image is labeled, except for the control image (H), which also has an inferior offset. N, T, and I represent nasal, temporal, and inferior, respectively. The cone mosaic was grossly disrupted in every case. Single or groupings of wave guiding cones surrounded by regions of absent or nondetectable cones composed the pattern observed in all areas. Cases 6 and 7, which showed an optical gap at the fovea on SD-OCT, also demonstrated severe disruption of the perifoveal cone mosaic (E, F, respectively; fovea marked as white asterisks). In case 5, there is additional image blur due to the presence of nystagmus and the retinal location is estimated.
    Figure Legend Snippet: (A–G) Macular cone photoreceptor morphology in six cases. The AOSLO images are shown for subsections of 2° by 2° fields, centered on the horizontal meridian, below a 2° horizontal section of SD-OCT that overlaps the region scanned by the AOSLO. The AOSLO images from similar eccentricities in a control subject are also provided (H–J). Each AO image is cropped from the original 2° by 2° frames to include regions in most focus. Horizontal bars on each of the AOSLO and SD-OCT images represent 0.4°. The approximate horizontal center of each AOSLO image is labeled, except for the control image (H), which also has an inferior offset. N, T, and I represent nasal, temporal, and inferior, respectively. The cone mosaic was grossly disrupted in every case. Single or groupings of wave guiding cones surrounded by regions of absent or nondetectable cones composed the pattern observed in all areas. Cases 6 and 7, which showed an optical gap at the fovea on SD-OCT, also demonstrated severe disruption of the perifoveal cone mosaic (E, F, respectively; fovea marked as white asterisks). In case 5, there is additional image blur due to the presence of nystagmus and the retinal location is estimated.

    Techniques Used: Labeling

    dull foveal reflex faint perifoveal hyperfluorescent ring presence  (Cell Signaling Technology Inc)


    Bioz Verified Symbol Cell Signaling Technology Inc is a verified supplier
    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
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  • About
  • News
  • Press Release
  • Team
  • Advisors
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  • Contact
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  • 86

    Structured Review

    Cell Signaling Technology Inc dull foveal reflex faint perifoveal hyperfluorescent ring presence
    Retinal Findings in the Cases at the Most Recent Visit
    Dull Foveal Reflex Faint Perifoveal Hyperfluorescent Ring Presence, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dull foveal reflex faint perifoveal hyperfluorescent ring presence/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    dull foveal reflex faint perifoveal hyperfluorescent ring presence - by Bioz Stars, 2023-02
    86/100 stars

    Images

    1) Product Images from "Phenotypic Characteristics Including In Vivo Cone Photoreceptor Mosaic in KCNV2- Related "Cone Dystrophy with Supernormal Rod Electroretinogram""

    Article Title: Phenotypic Characteristics Including In Vivo Cone Photoreceptor Mosaic in KCNV2- Related "Cone Dystrophy with Supernormal Rod Electroretinogram"

    Journal: Investigative ophthalmology & visual science

    doi: 10.1167/iovs.12-10971

    Retinal Findings in the Cases at the Most Recent Visit
    Figure Legend Snippet: Retinal Findings in the Cases at the Most Recent Visit

    Techniques Used: Tomography

    Fundus photographs (A–G), FAF images (H–N), and SD-OCT images (O–V) from one eye of all seven cases. Each horizontal panel represents corresponding fundus photo and FAF and SD-OCT images from the same eye of each individual case. Fundus photos show minimal retinal pigment epithelial changes at the macula in cases 2, 3, 6, and 7 (B, C, F, G). White boxes in fundus images represent 2° by 2° retinal locations from where AOSLO images were obtained. FAF showed a perifoveal ring of hyperfluorescence in five cases (white arrows in H, J–L, N). The SD-OCT (O–V) images show disruption of the IS-OS junction (asterisk) or optical gap (cross) at the fovea. (P) Foveal and (Q) perifoveal SD-OCT scans from the left eye of case 2 within the 2° by 2° square in Figure 1B, and demonstrate reasonable preservation of the IS-OS junction 250 μm inferior to fovea (Q) compared to the fovea (P). All the retinal layers are marked: ELM, external limitingmembrane; OPL, outer plexiform layer; IPL, inner plexiform layer; INL, inner nuclear layer; OS, photoreceptor outer segment; IS-OS, inner segment-outer segment junction. Photoreceptors within the white box on SD-OCT fall within the region scanned by AOSLO.
    Figure Legend Snippet: Fundus photographs (A–G), FAF images (H–N), and SD-OCT images (O–V) from one eye of all seven cases. Each horizontal panel represents corresponding fundus photo and FAF and SD-OCT images from the same eye of each individual case. Fundus photos show minimal retinal pigment epithelial changes at the macula in cases 2, 3, 6, and 7 (B, C, F, G). White boxes in fundus images represent 2° by 2° retinal locations from where AOSLO images were obtained. FAF showed a perifoveal ring of hyperfluorescence in five cases (white arrows in H, J–L, N). The SD-OCT (O–V) images show disruption of the IS-OS junction (asterisk) or optical gap (cross) at the fovea. (P) Foveal and (Q) perifoveal SD-OCT scans from the left eye of case 2 within the 2° by 2° square in Figure 1B, and demonstrate reasonable preservation of the IS-OS junction 250 μm inferior to fovea (Q) compared to the fovea (P). All the retinal layers are marked: ELM, external limitingmembrane; OPL, outer plexiform layer; IPL, inner plexiform layer; INL, inner nuclear layer; OS, photoreceptor outer segment; IS-OS, inner segment-outer segment junction. Photoreceptors within the white box on SD-OCT fall within the region scanned by AOSLO.

    Techniques Used: Preserving

    (A–G) Macular cone photoreceptor morphology in six cases. The AOSLO images are shown for subsections of 2° by 2° fields, centered on the horizontal meridian, below a 2° horizontal section of SD-OCT that overlaps the region scanned by the AOSLO. The AOSLO images from similar eccentricities in a control subject are also provided (H–J). Each AO image is cropped from the original 2° by 2° frames to include regions in most focus. Horizontal bars on each of the AOSLO and SD-OCT images represent 0.4°. The approximate horizontal center of each AOSLO image is labeled, except for the control image (H), which also has an inferior offset. N, T, and I represent nasal, temporal, and inferior, respectively. The cone mosaic was grossly disrupted in every case. Single or groupings of wave guiding cones surrounded by regions of absent or nondetectable cones composed the pattern observed in all areas. Cases 6 and 7, which showed an optical gap at the fovea on SD-OCT, also demonstrated severe disruption of the perifoveal cone mosaic (E, F, respectively; fovea marked as white asterisks). In case 5, there is additional image blur due to the presence of nystagmus and the retinal location is estimated.
    Figure Legend Snippet: (A–G) Macular cone photoreceptor morphology in six cases. The AOSLO images are shown for subsections of 2° by 2° fields, centered on the horizontal meridian, below a 2° horizontal section of SD-OCT that overlaps the region scanned by the AOSLO. The AOSLO images from similar eccentricities in a control subject are also provided (H–J). Each AO image is cropped from the original 2° by 2° frames to include regions in most focus. Horizontal bars on each of the AOSLO and SD-OCT images represent 0.4°. The approximate horizontal center of each AOSLO image is labeled, except for the control image (H), which also has an inferior offset. N, T, and I represent nasal, temporal, and inferior, respectively. The cone mosaic was grossly disrupted in every case. Single or groupings of wave guiding cones surrounded by regions of absent or nondetectable cones composed the pattern observed in all areas. Cases 6 and 7, which showed an optical gap at the fovea on SD-OCT, also demonstrated severe disruption of the perifoveal cone mosaic (E, F, respectively; fovea marked as white asterisks). In case 5, there is additional image blur due to the presence of nystagmus and the retinal location is estimated.

    Techniques Used: Labeling