constitutive androstane receptor car  (Cell Signaling Technology Inc)


Bioz Verified Symbol Cell Signaling Technology Inc is a verified supplier
Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Cell Signaling Technology Inc constitutive androstane receptor car
    Immunoblot analyses of (A) CYP450 isozymes and (B) PXR, <t>CAR</t> and P-gp of hepatic and intestinal microsomes in control (CON) and dextran sulfate sodium-induced ulcerative colitis (DSS) rats. β-actin was determined as a loading control. This experiment was completed three times. Band density was measured using ImageJ1.45s software (NIH). CAR, constitutive <t>androstane</t> receptor; PXR, pregnane X receptor; P-gp, P-glycoprotein.
    Constitutive Androstane Receptor Car, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/constitutive androstane receptor car/product/Cell Signaling Technology Inc
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    constitutive androstane receptor car - by Bioz Stars, 2023-02
    94/100 stars

    Images

    1) Product Images from "Effects of Dextran Sulfate Sodium-Induced Ulcerative Colitis on the Disposition of Tofacitinib in Rats"

    Article Title: Effects of Dextran Sulfate Sodium-Induced Ulcerative Colitis on the Disposition of Tofacitinib in Rats

    Journal: Biomolecules & Therapeutics

    doi: 10.4062/biomolther.2022.049

    Immunoblot analyses of (A) CYP450 isozymes and (B) PXR, CAR and P-gp of hepatic and intestinal microsomes in control (CON) and dextran sulfate sodium-induced ulcerative colitis (DSS) rats. β-actin was determined as a loading control. This experiment was completed three times. Band density was measured using ImageJ1.45s software (NIH). CAR, constitutive androstane receptor; PXR, pregnane X receptor; P-gp, P-glycoprotein.
    Figure Legend Snippet: Immunoblot analyses of (A) CYP450 isozymes and (B) PXR, CAR and P-gp of hepatic and intestinal microsomes in control (CON) and dextran sulfate sodium-induced ulcerative colitis (DSS) rats. β-actin was determined as a loading control. This experiment was completed three times. Band density was measured using ImageJ1.45s software (NIH). CAR, constitutive androstane receptor; PXR, pregnane X receptor; P-gp, P-glycoprotein.

    Techniques Used: Western Blot, Software

    constitutive androstane receptor car  (Cell Signaling Technology Inc)


    Bioz Verified Symbol Cell Signaling Technology Inc is a verified supplier
    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Cell Signaling Technology Inc constitutive androstane receptor car
    Immunoblot analyses of (A) CYP450 isozymes and (B) PXR, <t>CAR</t> and P-gp of hepatic and intestinal microsomes in control (CON) and dextran sulfate sodium-induced ulcerative colitis (DSS) rats. β-actin was determined as a loading control. This experiment was completed three times. Band density was measured using ImageJ1.45s software (NIH). CAR, constitutive <t>androstane</t> receptor; PXR, pregnane X receptor; P-gp, P-glycoprotein.
    Constitutive Androstane Receptor Car, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/constitutive androstane receptor car/product/Cell Signaling Technology Inc
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    constitutive androstane receptor car - by Bioz Stars, 2023-02
    94/100 stars

    Images

    1) Product Images from "Effects of Dextran Sulfate Sodium-Induced Ulcerative Colitis on the Disposition of Tofacitinib in Rats"

    Article Title: Effects of Dextran Sulfate Sodium-Induced Ulcerative Colitis on the Disposition of Tofacitinib in Rats

    Journal: Biomolecules & Therapeutics

    doi: 10.4062/biomolther.2022.049

    Immunoblot analyses of (A) CYP450 isozymes and (B) PXR, CAR and P-gp of hepatic and intestinal microsomes in control (CON) and dextran sulfate sodium-induced ulcerative colitis (DSS) rats. β-actin was determined as a loading control. This experiment was completed three times. Band density was measured using ImageJ1.45s software (NIH). CAR, constitutive androstane receptor; PXR, pregnane X receptor; P-gp, P-glycoprotein.
    Figure Legend Snippet: Immunoblot analyses of (A) CYP450 isozymes and (B) PXR, CAR and P-gp of hepatic and intestinal microsomes in control (CON) and dextran sulfate sodium-induced ulcerative colitis (DSS) rats. β-actin was determined as a loading control. This experiment was completed three times. Band density was measured using ImageJ1.45s software (NIH). CAR, constitutive androstane receptor; PXR, pregnane X receptor; P-gp, P-glycoprotein.

    Techniques Used: Western Blot, Software

    rabbit anti car  (Cell Signaling Technology Inc)


    Bioz Verified Symbol Cell Signaling Technology Inc is a verified supplier
    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Cell Signaling Technology Inc rabbit anti car
    Rabbit Anti Car, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti car/product/Cell Signaling Technology Inc
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti car - by Bioz Stars, 2023-02
    94/100 stars

    Images

    anti car  (Cell Signaling Technology Inc)


    Bioz Verified Symbol Cell Signaling Technology Inc is a verified supplier
    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Cell Signaling Technology Inc anti car
    Anti Car, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti car/product/Cell Signaling Technology Inc
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti car - by Bioz Stars, 2023-02
    94/100 stars

    Images

    anti car  (Cell Signaling Technology Inc)


    Bioz Verified Symbol Cell Signaling Technology Inc is a verified supplier
    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Cell Signaling Technology Inc anti car
    <t>CAR</t> Expression in KRAS mut Cells Is Not the Major Determinant of Increased Susceptibility of Adenocarcinomas to CVB3 (A and B) Protein levels of CAR in various adenocarcinoma and normal lung epithelial cells (A) or HPL1D cells stably expressing KRAS G12V in the presence or absence of doxycycline (100 ng/mL, 48 h) (B) by western blot analysis. CAR expression was quantitated by densitometric analysis using NIH ImageJ, normalized to β-actin, and presented underneath as fold changes compared with the first lane that is arbitrarily set at a value of 1. (C and D) Inhibition of KRAS (C) or ERK1/2 (D) activation results in increased CAR expression in KRAS mut lung adenocarcinoma cells. H23 and H2030 cells were treated with or without the KRAS G12C inhibitor ARS853 (50 nM) or MEK1/2 inhibitor U0126 (20 μM) as indicated for 24 h, followed by western blot and densitometric analysis of CAR as above. (E) CXARD mRNA levels (RSEM scaled estimate values) in various lung adenocarcinomas. A total of 230 human lung adenocarcinoma tumors were grouped by genotype ( KRAS mut <t>,</t> <t>EGFR</t> mut , or EGFR/KRAS wild-type ), and expression values were compared between groups using the Mann-Whiney U test in Prism 7 (GraphPad). No statistical significance between groups was observed. (F) HPL1D cell lines stably expressing GFP , KRAS G12V , or EGFR L858R were infected with CVB3 at different MOIs as indicated for 30 min. After PBS washing, cells were collected for RNA extraction. Virus uptake was determined by qPCR analysis of viral genomic RNA (means ± SD, n = 3). There are no statistical differences in virus uptake between control and KRAS mut or EGFR mut cells.
    Anti Car, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti car/product/Cell Signaling Technology Inc
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti car - by Bioz Stars, 2023-02
    94/100 stars

    Images

    1) Product Images from "Coxsackievirus Type B3 Is a Potent Oncolytic Virus against KRAS -Mutant Lung Adenocarcinoma"

    Article Title: Coxsackievirus Type B3 Is a Potent Oncolytic Virus against KRAS -Mutant Lung Adenocarcinoma

    Journal: Molecular Therapy Oncolytics

    doi: 10.1016/j.omto.2019.07.003

    CAR Expression in KRAS mut Cells Is Not the Major Determinant of Increased Susceptibility of Adenocarcinomas to CVB3 (A and B) Protein levels of CAR in various adenocarcinoma and normal lung epithelial cells (A) or HPL1D cells stably expressing KRAS G12V in the presence or absence of doxycycline (100 ng/mL, 48 h) (B) by western blot analysis. CAR expression was quantitated by densitometric analysis using NIH ImageJ, normalized to β-actin, and presented underneath as fold changes compared with the first lane that is arbitrarily set at a value of 1. (C and D) Inhibition of KRAS (C) or ERK1/2 (D) activation results in increased CAR expression in KRAS mut lung adenocarcinoma cells. H23 and H2030 cells were treated with or without the KRAS G12C inhibitor ARS853 (50 nM) or MEK1/2 inhibitor U0126 (20 μM) as indicated for 24 h, followed by western blot and densitometric analysis of CAR as above. (E) CXARD mRNA levels (RSEM scaled estimate values) in various lung adenocarcinomas. A total of 230 human lung adenocarcinoma tumors were grouped by genotype ( KRAS mut , EGFR mut , or EGFR/KRAS wild-type ), and expression values were compared between groups using the Mann-Whiney U test in Prism 7 (GraphPad). No statistical significance between groups was observed. (F) HPL1D cell lines stably expressing GFP , KRAS G12V , or EGFR L858R were infected with CVB3 at different MOIs as indicated for 30 min. After PBS washing, cells were collected for RNA extraction. Virus uptake was determined by qPCR analysis of viral genomic RNA (means ± SD, n = 3). There are no statistical differences in virus uptake between control and KRAS mut or EGFR mut cells.
    Figure Legend Snippet: CAR Expression in KRAS mut Cells Is Not the Major Determinant of Increased Susceptibility of Adenocarcinomas to CVB3 (A and B) Protein levels of CAR in various adenocarcinoma and normal lung epithelial cells (A) or HPL1D cells stably expressing KRAS G12V in the presence or absence of doxycycline (100 ng/mL, 48 h) (B) by western blot analysis. CAR expression was quantitated by densitometric analysis using NIH ImageJ, normalized to β-actin, and presented underneath as fold changes compared with the first lane that is arbitrarily set at a value of 1. (C and D) Inhibition of KRAS (C) or ERK1/2 (D) activation results in increased CAR expression in KRAS mut lung adenocarcinoma cells. H23 and H2030 cells were treated with or without the KRAS G12C inhibitor ARS853 (50 nM) or MEK1/2 inhibitor U0126 (20 μM) as indicated for 24 h, followed by western blot and densitometric analysis of CAR as above. (E) CXARD mRNA levels (RSEM scaled estimate values) in various lung adenocarcinomas. A total of 230 human lung adenocarcinoma tumors were grouped by genotype ( KRAS mut , EGFR mut , or EGFR/KRAS wild-type ), and expression values were compared between groups using the Mann-Whiney U test in Prism 7 (GraphPad). No statistical significance between groups was observed. (F) HPL1D cell lines stably expressing GFP , KRAS G12V , or EGFR L858R were infected with CVB3 at different MOIs as indicated for 30 min. After PBS washing, cells were collected for RNA extraction. Virus uptake was determined by qPCR analysis of viral genomic RNA (means ± SD, n = 3). There are no statistical differences in virus uptake between control and KRAS mut or EGFR mut cells.

    Techniques Used: Expressing, Stable Transfection, Western Blot, Inhibition, Activation Assay, Infection, RNA Extraction

    primary anti car  (Cell Signaling Technology Inc)


    Bioz Verified Symbol Cell Signaling Technology Inc is a verified supplier
    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Cell Signaling Technology Inc primary anti car
    Expression of coxsackie and adenovirus receptor <t>(CAR)</t> <t>and</t> <t>integrin</t> αvβ3 (INT) in human and murine glioma cells. (A) CAR and (B) integrin αvβ3 expression was determined by Western blot analysis in human glioma cell lines (U251, U87), cultures from human glioma biopsies (IN859, IN 2045), rat (CNS-1), and mouse (GL26) glioma cells. CHO and HeLa cells were used as negative and positive controls, respectively. β-Actin was used as loading control. The tops show Western blots for CAR (A), INT (B), and β-actin from glioma, CHO, and HeLa cell lysates. The bottom panels show the integrated density values of CAR or INT in relation to β-actin expression for all cells analyzed.
    Primary Anti Car, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/primary anti car/product/Cell Signaling Technology Inc
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    primary anti car - by Bioz Stars, 2023-02
    94/100 stars

    Images

    1) Product Images from "Effective High-Capacity Gutless Adenoviral Vectors Mediate Transgene Expression in Human Glioma Cells"

    Article Title: Effective High-Capacity Gutless Adenoviral Vectors Mediate Transgene Expression in Human Glioma Cells

    Journal:

    doi: 10.1016/j.ymthe.2006.05.006

    Expression of coxsackie and adenovirus receptor (CAR) and integrin αvβ3 (INT) in human and murine glioma cells. (A) CAR and (B) integrin αvβ3 expression was determined by Western blot analysis in human glioma cell lines (U251, U87), cultures from human glioma biopsies (IN859, IN 2045), rat (CNS-1), and mouse (GL26) glioma cells. CHO and HeLa cells were used as negative and positive controls, respectively. β-Actin was used as loading control. The tops show Western blots for CAR (A), INT (B), and β-actin from glioma, CHO, and HeLa cell lysates. The bottom panels show the integrated density values of CAR or INT in relation to β-actin expression for all cells analyzed.
    Figure Legend Snippet: Expression of coxsackie and adenovirus receptor (CAR) and integrin αvβ3 (INT) in human and murine glioma cells. (A) CAR and (B) integrin αvβ3 expression was determined by Western blot analysis in human glioma cell lines (U251, U87), cultures from human glioma biopsies (IN859, IN 2045), rat (CNS-1), and mouse (GL26) glioma cells. CHO and HeLa cells were used as negative and positive controls, respectively. β-Actin was used as loading control. The tops show Western blots for CAR (A), INT (B), and β-actin from glioma, CHO, and HeLa cell lysates. The bottom panels show the integrated density values of CAR or INT in relation to β-actin expression for all cells analyzed.

    Techniques Used: Expressing, Western Blot

    Similar Products

  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94
    Cell Signaling Technology Inc constitutive androstane receptor car
    Immunoblot analyses of (A) CYP450 isozymes and (B) PXR, <t>CAR</t> and P-gp of hepatic and intestinal microsomes in control (CON) and dextran sulfate sodium-induced ulcerative colitis (DSS) rats. β-actin was determined as a loading control. This experiment was completed three times. Band density was measured using ImageJ1.45s software (NIH). CAR, constitutive <t>androstane</t> receptor; PXR, pregnane X receptor; P-gp, P-glycoprotein.
    Constitutive Androstane Receptor Car, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/constitutive androstane receptor car/product/Cell Signaling Technology Inc
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    constitutive androstane receptor car - by Bioz Stars, 2023-02
    94/100 stars
      Buy from Supplier

    94
    Cell Signaling Technology Inc rabbit anti car
    Immunoblot analyses of (A) CYP450 isozymes and (B) PXR, <t>CAR</t> and P-gp of hepatic and intestinal microsomes in control (CON) and dextran sulfate sodium-induced ulcerative colitis (DSS) rats. β-actin was determined as a loading control. This experiment was completed three times. Band density was measured using ImageJ1.45s software (NIH). CAR, constitutive <t>androstane</t> receptor; PXR, pregnane X receptor; P-gp, P-glycoprotein.
    Rabbit Anti Car, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti car/product/Cell Signaling Technology Inc
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti car - by Bioz Stars, 2023-02
    94/100 stars
      Buy from Supplier

    94
    Cell Signaling Technology Inc anti car
    Immunoblot analyses of (A) CYP450 isozymes and (B) PXR, <t>CAR</t> and P-gp of hepatic and intestinal microsomes in control (CON) and dextran sulfate sodium-induced ulcerative colitis (DSS) rats. β-actin was determined as a loading control. This experiment was completed three times. Band density was measured using ImageJ1.45s software (NIH). CAR, constitutive <t>androstane</t> receptor; PXR, pregnane X receptor; P-gp, P-glycoprotein.
    Anti Car, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti car/product/Cell Signaling Technology Inc
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti car - by Bioz Stars, 2023-02
    94/100 stars
      Buy from Supplier

    94
    Cell Signaling Technology Inc primary anti car
    Expression of coxsackie and adenovirus receptor <t>(CAR)</t> <t>and</t> <t>integrin</t> αvβ3 (INT) in human and murine glioma cells. (A) CAR and (B) integrin αvβ3 expression was determined by Western blot analysis in human glioma cell lines (U251, U87), cultures from human glioma biopsies (IN859, IN 2045), rat (CNS-1), and mouse (GL26) glioma cells. CHO and HeLa cells were used as negative and positive controls, respectively. β-Actin was used as loading control. The tops show Western blots for CAR (A), INT (B), and β-actin from glioma, CHO, and HeLa cell lysates. The bottom panels show the integrated density values of CAR or INT in relation to β-actin expression for all cells analyzed.
    Primary Anti Car, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/primary anti car/product/Cell Signaling Technology Inc
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    primary anti car - by Bioz Stars, 2023-02
    94/100 stars
      Buy from Supplier

    Image Search Results


    Immunoblot analyses of (A) CYP450 isozymes and (B) PXR, CAR and P-gp of hepatic and intestinal microsomes in control (CON) and dextran sulfate sodium-induced ulcerative colitis (DSS) rats. β-actin was determined as a loading control. This experiment was completed three times. Band density was measured using ImageJ1.45s software (NIH). CAR, constitutive androstane receptor; PXR, pregnane X receptor; P-gp, P-glycoprotein.

    Journal: Biomolecules & Therapeutics

    Article Title: Effects of Dextran Sulfate Sodium-Induced Ulcerative Colitis on the Disposition of Tofacitinib in Rats

    doi: 10.4062/biomolther.2022.049

    Figure Lengend Snippet: Immunoblot analyses of (A) CYP450 isozymes and (B) PXR, CAR and P-gp of hepatic and intestinal microsomes in control (CON) and dextran sulfate sodium-induced ulcerative colitis (DSS) rats. β-actin was determined as a loading control. This experiment was completed three times. Band density was measured using ImageJ1.45s software (NIH). CAR, constitutive androstane receptor; PXR, pregnane X receptor; P-gp, P-glycoprotein.

    Article Snippet: Primary antibodies against pregnane X receptor (PXR), constitutive androstane receptor (CAR), P-gp and β-actin were purchased from Cell Signaling Technology (Beverly, MA, USA).

    Techniques: Western Blot, Software

    Expression of coxsackie and adenovirus receptor (CAR) and integrin αvβ3 (INT) in human and murine glioma cells. (A) CAR and (B) integrin αvβ3 expression was determined by Western blot analysis in human glioma cell lines (U251, U87), cultures from human glioma biopsies (IN859, IN 2045), rat (CNS-1), and mouse (GL26) glioma cells. CHO and HeLa cells were used as negative and positive controls, respectively. β-Actin was used as loading control. The tops show Western blots for CAR (A), INT (B), and β-actin from glioma, CHO, and HeLa cell lysates. The bottom panels show the integrated density values of CAR or INT in relation to β-actin expression for all cells analyzed.

    Journal:

    Article Title: Effective High-Capacity Gutless Adenoviral Vectors Mediate Transgene Expression in Human Glioma Cells

    doi: 10.1016/j.ymthe.2006.05.006

    Figure Lengend Snippet: Expression of coxsackie and adenovirus receptor (CAR) and integrin αvβ3 (INT) in human and murine glioma cells. (A) CAR and (B) integrin αvβ3 expression was determined by Western blot analysis in human glioma cell lines (U251, U87), cultures from human glioma biopsies (IN859, IN 2045), rat (CNS-1), and mouse (GL26) glioma cells. CHO and HeLa cells were used as negative and positive controls, respectively. β-Actin was used as loading control. The tops show Western blots for CAR (A), INT (B), and β-actin from glioma, CHO, and HeLa cell lysates. The bottom panels show the integrated density values of CAR or INT in relation to β-actin expression for all cells analyzed.

    Article Snippet: Primary anti-CAR (Upstate Cell Signaling Solutions), anti-integrin α v β 3 (Chemicon International), or anti-actin antibodies (Sigma) were detected with HRP-conjugated antibodies and developed with an ECL kit (Amersham Biosciences).

    Techniques: Expressing, Western Blot