Journal: Scientific Reports

Article Title: Optogenetic restoration of high sensitivity vision with bReaChES, a red-shifted channelrhodopsin

doi: 10.1038/s41598-022-23572-4

Figure Lengend Snippet: Neural activation of the visual cortex as measured by c-Fos expression following ocular light stimulation. c-Fos expression in untreated wild-type ( A , B ), untreated dystrophic ( C , D ) and bReaChES-treated dystrophic ( E , F ) mice. ( G ) Number of c-Fos-positive cells in the visual cortex demonstrating restoration of anatomical visual drive to the cortex in treated dystrophic mice (N = 3 mice per group). Abbreviation: WT = wild-type; Dys = dystrophic). Scale bar = 200um. Error bars indicate ± SD. * p < 0.05, one-way ANOVA with two-sided Dunnett’s test.

Article Snippet: c-Fos (9F6) monoclonal antibody , Cell Signalling Technology , #2250.

Techniques: Activation Assay, Expressing

Journal: Scientific Reports

Article Title: Optogenetic restoration of high sensitivity vision with bReaChES, a red-shifted channelrhodopsin

doi: 10.1038/s41598-022-23572-4

Figure Lengend Snippet: Star methods resources table.

Article Snippet: c-Fos (9F6) monoclonal antibody , Cell Signalling Technology , #2250.

Techniques: Staining, Software, Injection, Imaging