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NeuroNexus Technologies 64 channel optrode
Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. <t>The</t> <t>64-channel</t> optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).
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Thorlabs optrodes thorlabs inc part no
Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. <t>The</t> <t>64-channel</t> optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).
Optrodes Thorlabs Inc Part No, supplied by Thorlabs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Thorlabs mri compatible carbon fiber optrodes
Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. <t>The</t> <t>64-channel</t> optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).
Mri Compatible Carbon Fiber Optrodes, supplied by Thorlabs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Thorlabs optrodes
Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. <t>The</t> <t>64-channel</t> optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).
Optrodes, supplied by Thorlabs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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NeuroNexus Technologies multisite electrode
Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. <t>The</t> <t>64-channel</t> optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).
Multisite Electrode, supplied by NeuroNexus Technologies, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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NeuroNexus Technologies channel silicon probe
Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. <t>The</t> <t>64-channel</t> optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).
Channel Silicon Probe, supplied by NeuroNexus Technologies, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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NeuroNexus Technologies silicone shank
Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. <t>The</t> <t>64-channel</t> optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).
Silicone Shank, supplied by NeuroNexus Technologies, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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NeuroNexus Technologies neuronexus a1x16
Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. <t>The</t> <t>64-channel</t> optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).
Neuronexus A1x16, supplied by NeuroNexus Technologies, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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NeuroNexus Technologies omicron luxx 473 100 recording optrode
Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. <t>The</t> <t>64-channel</t> optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).
Omicron Luxx 473 100 Recording Optrode, supplied by NeuroNexus Technologies, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. The 64-channel optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).

Journal: bioRxiv

Article Title: Cell-Type-Specific Bidirectional Modulation of the Cortico–Thalamo–Cortical Sensory Pathway by Transcranial Focused Ultrasound (tFUS)

doi: 10.64898/2026.03.23.713540

Figure Lengend Snippet: Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. The 64-channel optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).

Article Snippet: A 64-channel Optrode (A1×64-Edge-6mm-22.5-177-OXA64LP, Neuronexus, Ann Arbor, MI, USA) was inserted into S1 from the left side (angle: 40°) to make sure the signals were recorded from the virus injection site.

Techniques: Sonication, Ex Vivo