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microarray-based ribonomics approach  (Ribonomics Inc)

 
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    Ribonomics Inc microarray-based ribonomics approach
    Microarray Based Ribonomics Approach, supplied by Ribonomics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/microarray-based+assay/microarray+based+ribonomics+approach/pmc02040218-107-4-5
    Average 90 stars, based on 1 article reviews
    microarray-based ribonomics approach - by Bioz Stars, 2026-09
    90/100 stars

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    other:

    Article Title: A comprehensive in silico expression analysis of RNA binding proteins in normal and tumor tissue
    Article Snippet: The development of recent tools and methods like the RIP-Chip/Ribonomics assay, CLIP and alternative splicing microarrays 29 – 32 will accelerate the understanding of RBPs participation in tumorigenesis.

    Article Title: HuR-Regulated mRNAs Associated with Nuclear hnRNP A1-RNP Complexes
    Article Snippet: To this extent, we report here on the novel application of the Ribonomics (RIP-Chip) platform on hnRNP A1-RNP complexes immunoselected from the nuclear extracts of HuR-lacking and HuR-containing mouse embryonic fibroblast (MEF) cells.

    Article Title: Defects in Translational Regulation contributing to Human Cognitive and Behavioral Disease
    Article Snippet: Previous approaches have included in vitro RNA selection [ 77 , 78 ] and co-IP followed by either microarray (RIP-Chip, also called “ribonomics”) [ 79 ] or by directed PCR for candidate mRNA ligands.

    Article Title: Profiling post-transcriptionally networked mRNA subsets using RIP-Chip and RIP-Seq
    Article Snippet: Keywords: RIP-Chip, Rip-Seq, Ribonomics, mRNA localization, RNA-binding proteins (RBPs), Post-Transcription, microarray expression profiling

    Article Title: Musashi1: an RBP with versatile functions in normal and cancer stem cells.
    Article Snippet: Musashi1 (Msi1) is a highly conserved RNA binding protein that was initially identified in Drosophila by its ability to regulate sensory organ development and asymmetric cell division.. Studies in mammalian cells reveal multiple functions for Musashi1 in normal and abnormal processes by mediating different posttranscriptional processes.. According to our recent studies, Musashi1 very likely controls hundreds of targets, forming networks that regulate apoptosis, differentiation, proliferation and cell cycle.

    Article Title: HuR-Regulated mRNAs Associated with Nuclear hnRNP A1-RNP Complexes
    Article Snippet: The Ribonomics platform (RIP-Chip assay) refers to Ribonucleoprotein (RNP) ImmunoPrecipitation (RIP) followed by microarray (Chip) analysis.

    Microarray:

    Article Title: Methods for identifying functionally related genes and drug targets
    Article Snippet: The RiboChipTM (Ribonomics, Durham, N.C.) was composed of oligonucleotides complementary to greater than 1400 RNA Binding Protein genes plus controls. .. Alternatively a RiboChipTM microarray (Ribonomics, Durham, N.C.) may also include a comprehensive collection of transcription factors to represent the full set of sentinel genes for the quantitative and qualitative assessment of toxicity. ..

    Article Title: Methods for identifying functionally related genes and drug targets
    Article Snippet: .. For more rapid and comprehensive screening of tissues and cell lines, a custom RIBOCHIPTM spotted microarray (Ribonomics, Inc., Durham, N.C.) was designed and manufactured under contract (MWG Biotech USA, Highpoint, N.C.). .. A gene list of known and putative human RNA binding protein genes was compiled from a wide variety of public databases and search tools including GenBank (NCBI, Bethesda, Md.), PubMed (NCBI, Bethesda, Md.), SRS Evolution (LION Biosciences, Cambridge, Mass.), LocusLink (NCBI, Bethesda, Md.), Protein FAMily database (pFAM); Welcome Institute Sanger Institute, Hinxton, UK), GO Database (Gene OntologyTM Consortium) and Structural Classification of Proteins (SCOP©) Package (Medical Research Council, Cambridge, UK).



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    Cell type specific genes demonstrated at mRNA level. (A) Heat map of genes with cell type specific expression. (B) Heat map of selected genes with endothelial or epithelial cell type specific expression. (C) Immunohistochemistry staining of protein C1orf116 across human tissues showing its epithelial cell type specific expression. The panel shows a magnified view (20×) from tissue microarrays.

    Journal: Nucleic Acids Research

    Article Title: A transcriptomic and proteomic map of primary human cell types

    doi: 10.1093/nar/gkaf1498

    Figure Lengend Snippet: Cell type specific genes demonstrated at mRNA level. (A) Heat map of genes with cell type specific expression. (B) Heat map of selected genes with endothelial or epithelial cell type specific expression. (C) Immunohistochemistry staining of protein C1orf116 across human tissues showing its epithelial cell type specific expression. The panel shows a magnified view (20×) from tissue microarrays.

    Article Snippet: The Human Protein Atlas (HPA) project provided a tissue-based map of the human proteome through transcriptomics and tissue microarray-based immunohistochemistry analysis [ , ].

    Techniques: Expressing, Immunohistochemistry, Staining