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bivalirudin  (MedChemExpress)


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    Structured Review

    MedChemExpress bivalirudin
    Comparative safety outcomes of algal hirudin and conventional anticoagulants in mice. (A) Incidence and severity of platelet count reduction after treatment. The stacked bars show the percentage of mice in each treatment group with mild (<35% drop), moderate (35–65% drop), or severe (>65% drop) thrombocytopenia. The number of mice per group (n) was 31 for Cr -Hirudin, 35 for <t>bivalirudin,</t> and 37 for heparin. (B) Percentage of mice exhibiting significant bleeding upon necropsy for each treatment group. The number of animals assessed (n) was 65 for Cr -Hirudin, 35 for bivalirudin, and 37 for heparin.
    Bivalirudin, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy-p1929/Bivalirudin/bio_rxiv__2025__09__25__678210-70-31-32
    Average 94 stars, based on 2 article reviews
    bivalirudin - by Bioz Stars, 2026-10
    94/100 stars

    Images

    1) Product Images from "Expression screening and functional verification of recombinant hirudin from novel chassis cell Chlamydomonas reinhardtii"

    Article Title: Expression screening and functional verification of recombinant hirudin from novel chassis cell Chlamydomonas reinhardtii

    Journal: bioRxiv

    doi: 10.1101/2025.09.25.678210

    Comparative safety outcomes of algal hirudin and conventional anticoagulants in mice. (A) Incidence and severity of platelet count reduction after treatment. The stacked bars show the percentage of mice in each treatment group with mild (<35% drop), moderate (35–65% drop), or severe (>65% drop) thrombocytopenia. The number of mice per group (n) was 31 for Cr -Hirudin, 35 for bivalirudin, and 37 for heparin. (B) Percentage of mice exhibiting significant bleeding upon necropsy for each treatment group. The number of animals assessed (n) was 65 for Cr -Hirudin, 35 for bivalirudin, and 37 for heparin.
    Figure Legend Snippet: Comparative safety outcomes of algal hirudin and conventional anticoagulants in mice. (A) Incidence and severity of platelet count reduction after treatment. The stacked bars show the percentage of mice in each treatment group with mild (<35% drop), moderate (35–65% drop), or severe (>65% drop) thrombocytopenia. The number of mice per group (n) was 31 for Cr -Hirudin, 35 for bivalirudin, and 37 for heparin. (B) Percentage of mice exhibiting significant bleeding upon necropsy for each treatment group. The number of animals assessed (n) was 65 for Cr -Hirudin, 35 for bivalirudin, and 37 for heparin.

    Techniques Used:

    Related Articles

    Recombinant:

    Article Title: Expression screening and functional verification of recombinant hirudin from novel chassis cell Chlamydomonas reinhardtii
    Article Snippet: .. The animals were assigned to one of three treatment groups: (1) oral gavage administration of 0.1 mg/kg recombinant hirudin contained within C. reinhardtii biomass; (2) intraperitoneal (i.p.) injection of 2 mg/kg bivalirudin (MCE, HY-P1929); or (3) i.p. injection of 4 U/mouse heparin (MCE, HY-17567C). ..

    Injection:

    Article Title: Expression screening and functional verification of recombinant hirudin from novel chassis cell Chlamydomonas reinhardtii
    Article Snippet: .. The animals were assigned to one of three treatment groups: (1) oral gavage administration of 0.1 mg/kg recombinant hirudin contained within C. reinhardtii biomass; (2) intraperitoneal (i.p.) injection of 2 mg/kg bivalirudin (MCE, HY-P1929); or (3) i.p. injection of 4 U/mouse heparin (MCE, HY-17567C). ..



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    94
    MedChemExpress bivalirudin
    Comparative safety outcomes of algal hirudin and conventional anticoagulants in mice. (A) Incidence and severity of platelet count reduction after treatment. The stacked bars show the percentage of mice in each treatment group with mild (<35% drop), moderate (35–65% drop), or severe (>65% drop) thrombocytopenia. The number of mice per group (n) was 31 for Cr -Hirudin, 35 for <t>bivalirudin,</t> and 37 for heparin. (B) Percentage of mice exhibiting significant bleeding upon necropsy for each treatment group. The number of animals assessed (n) was 65 for Cr -Hirudin, 35 for bivalirudin, and 37 for heparin.
    Bivalirudin, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy-p1929/Bivalirudin/bio_rxiv__2025__09__25__678210-70-31-32
    Average 94 stars, based on 1 article reviews
    bivalirudin - by Bioz Stars, 2026-10
    94/100 stars
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    Comparative safety outcomes of algal hirudin and conventional anticoagulants in mice. (A) Incidence and severity of platelet count reduction after treatment. The stacked bars show the percentage of mice in each treatment group with mild (<35% drop), moderate (35–65% drop), or severe (>65% drop) thrombocytopenia. The number of mice per group (n) was 31 for Cr -Hirudin, 35 for bivalirudin, and 37 for heparin. (B) Percentage of mice exhibiting significant bleeding upon necropsy for each treatment group. The number of animals assessed (n) was 65 for Cr -Hirudin, 35 for bivalirudin, and 37 for heparin.

    Journal: bioRxiv

    Article Title: Expression screening and functional verification of recombinant hirudin from novel chassis cell Chlamydomonas reinhardtii

    doi: 10.1101/2025.09.25.678210

    Figure Lengend Snippet: Comparative safety outcomes of algal hirudin and conventional anticoagulants in mice. (A) Incidence and severity of platelet count reduction after treatment. The stacked bars show the percentage of mice in each treatment group with mild (<35% drop), moderate (35–65% drop), or severe (>65% drop) thrombocytopenia. The number of mice per group (n) was 31 for Cr -Hirudin, 35 for bivalirudin, and 37 for heparin. (B) Percentage of mice exhibiting significant bleeding upon necropsy for each treatment group. The number of animals assessed (n) was 65 for Cr -Hirudin, 35 for bivalirudin, and 37 for heparin.

    Article Snippet: The animals were assigned to one of three treatment groups: (1) oral gavage administration of 0.1 mg/kg recombinant hirudin contained within C. reinhardtii biomass; (2) intraperitoneal (i.p.) injection of 2 mg/kg bivalirudin (MCE, HY-P1929); or (3) i.p. injection of 4 U/mouse heparin (MCE, HY-17567C).

    Techniques: