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tumor necrosis factor alpha  (MedChemExpress)


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    MedChemExpress tumor necrosis factor alpha
    Tumor Necrosis Factor Alpha, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 17 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy-p1860/TNF-%CE%B1+(31-45)%2C+human/pm42537812-47-0-8
    Average 94 stars, based on 17 article reviews
    tumor necrosis factor alpha - by Bioz Stars, 2026-10
    94/100 stars

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    Saline:

    Article Title: Ouabain Relieves Sleep Deprivation–Induced Anxiety‐Like Behavior in Mice by Suppressing Hippocampal Neuroinflammation and Oxidative Stress
    Article Snippet: .. Ouabain (≥ 98% purity; CAS 11018‐89‐6; Sigma, St. Louis, USA), SU6656 (HY‐B0789; MedChemExpress, USA), anisomycin (HY‐18982; MedChemExpress), and TNF‐α (HY‐P1860; MedChemExpress) were dissolved in DMSO and then diluted with normal saline to appropriate concentrations before use. ..



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    Ouabain attenuates hippocampal inflammatory responses and oxidative stress induced by acute sleep deprivation. Hippocampal levels <t>of</t> <t>TNF‐α</t> (A), IL‐1β (B), IL‐4 (C), and IL‐10 (D). ELISA detection of MDA (E), SOD (F), GPx (G), GR (H), CAT (I), and T‐AOC (J). N = 5/group. Ctl + Ouabain, control group treated with ouabain; Ctl + Saline, control group treated with saline; SD + Ouabain, acute sleep deprivation group treated with ouabain; SD + Saline, acute sleep deprivation group treated with saline. * p < 0.05, ** p < 0.01.
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    Treprostinil promotes endothelial cell survival and viability (A) TUNEL staining showed that treprostinil significantly inhibited the apoptosis of human umbilical vein endothelial cells (HUVECs) induced by tumor <t>necrosis</t> <t>factor-α</t> ( n = 3 biological samples per group). Scale bars, 50 μm (B–D) CCK8 and qPCR analyses suggested that treprostinil promoted cell viability and reduced inflammation in HUVECs ( n = 6 biological samples per group). Two-tailed unpaired Student’s t test was used to calculate statistical significance. Data are represented as mean ± SEM. ∗ represents p < 0.05, ∗∗ represents p < 0.01, and ∗∗∗ represents p < 0.001.
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    Treprostinil promotes endothelial cell survival and viability (A) TUNEL staining showed that treprostinil significantly inhibited the apoptosis of human umbilical vein endothelial cells (HUVECs) induced by tumor <t>necrosis</t> <t>factor-α</t> ( n = 3 biological samples per group). Scale bars, 50 μm (B–D) CCK8 and qPCR analyses suggested that treprostinil promoted cell viability and reduced inflammation in HUVECs ( n = 6 biological samples per group). Two-tailed unpaired Student’s t test was used to calculate statistical significance. Data are represented as mean ± SEM. ∗ represents p < 0.05, ∗∗ represents p < 0.01, and ∗∗∗ represents p < 0.001.
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    Treprostinil promotes endothelial cell survival and viability (A) TUNEL staining showed that treprostinil significantly inhibited the apoptosis of human umbilical vein endothelial cells (HUVECs) induced by tumor <t>necrosis</t> <t>factor-α</t> ( n = 3 biological samples per group). Scale bars, 50 μm (B–D) CCK8 and qPCR analyses suggested that treprostinil promoted cell viability and reduced inflammation in HUVECs ( n = 6 biological samples per group). Two-tailed unpaired Student’s t test was used to calculate statistical significance. Data are represented as mean ± SEM. ∗ represents p < 0.05, ∗∗ represents p < 0.01, and ∗∗∗ represents p < 0.001.
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    Image Search Results


    Ouabain attenuates hippocampal inflammatory responses and oxidative stress induced by acute sleep deprivation. Hippocampal levels of TNF‐α (A), IL‐1β (B), IL‐4 (C), and IL‐10 (D). ELISA detection of MDA (E), SOD (F), GPx (G), GR (H), CAT (I), and T‐AOC (J). N = 5/group. Ctl + Ouabain, control group treated with ouabain; Ctl + Saline, control group treated with saline; SD + Ouabain, acute sleep deprivation group treated with ouabain; SD + Saline, acute sleep deprivation group treated with saline. * p < 0.05, ** p < 0.01.

    Journal: Brain and Behavior

    Article Title: Ouabain Relieves Sleep Deprivation–Induced Anxiety‐Like Behavior in Mice by Suppressing Hippocampal Neuroinflammation and Oxidative Stress

    doi: 10.1002/brb3.71629

    Figure Lengend Snippet: Ouabain attenuates hippocampal inflammatory responses and oxidative stress induced by acute sleep deprivation. Hippocampal levels of TNF‐α (A), IL‐1β (B), IL‐4 (C), and IL‐10 (D). ELISA detection of MDA (E), SOD (F), GPx (G), GR (H), CAT (I), and T‐AOC (J). N = 5/group. Ctl + Ouabain, control group treated with ouabain; Ctl + Saline, control group treated with saline; SD + Ouabain, acute sleep deprivation group treated with ouabain; SD + Saline, acute sleep deprivation group treated with saline. * p < 0.05, ** p < 0.01.

    Article Snippet: Ouabain (≥ 98% purity; CAS 11018‐89‐6; Sigma, St. Louis, USA), SU6656 (HY‐B0789; MedChemExpress, USA), anisomycin (HY‐18982; MedChemExpress), and TNF‐α (HY‐P1860; MedChemExpress) were dissolved in DMSO and then diluted with normal saline to appropriate concentrations before use.

    Techniques: Enzyme-linked Immunosorbent Assay, Control, Saline

    Microglial depletion alleviates acute sleep deprivation–induced hippocampal inflammation and oxidative stress. Hippocampal levels of TNF‐α (A), IL‐1β (B), IL‐4 (C), IL‐10 (D). ELISA detection of MDA (E), SOD (F), GPx (G), GR (H), CAT (I), and T‐AOC (J). N = 5/group. Ctl + AIN‐76A, control group treated with base diet; Ctl + PLX5622, control group treated with PLX5622; SD + AIN‐76A, acute sleep deprivation group treated with base diet; SD + PLX5622, acute sleep deprivation group treated with PLX5622. * p < 0.05, ** p < 0.01.

    Journal: Brain and Behavior

    Article Title: Ouabain Relieves Sleep Deprivation–Induced Anxiety‐Like Behavior in Mice by Suppressing Hippocampal Neuroinflammation and Oxidative Stress

    doi: 10.1002/brb3.71629

    Figure Lengend Snippet: Microglial depletion alleviates acute sleep deprivation–induced hippocampal inflammation and oxidative stress. Hippocampal levels of TNF‐α (A), IL‐1β (B), IL‐4 (C), IL‐10 (D). ELISA detection of MDA (E), SOD (F), GPx (G), GR (H), CAT (I), and T‐AOC (J). N = 5/group. Ctl + AIN‐76A, control group treated with base diet; Ctl + PLX5622, control group treated with PLX5622; SD + AIN‐76A, acute sleep deprivation group treated with base diet; SD + PLX5622, acute sleep deprivation group treated with PLX5622. * p < 0.05, ** p < 0.01.

    Article Snippet: Ouabain (≥ 98% purity; CAS 11018‐89‐6; Sigma, St. Louis, USA), SU6656 (HY‐B0789; MedChemExpress, USA), anisomycin (HY‐18982; MedChemExpress), and TNF‐α (HY‐P1860; MedChemExpress) were dissolved in DMSO and then diluted with normal saline to appropriate concentrations before use.

    Techniques: Enzyme-linked Immunosorbent Assay, Control

    Ouabain's antioxidant and anti‐inflammatory effects depends on the Src/p38 MAPK/NF‐κB pathway. Hippocampal levels of TNF‐α (A), IL‐1β (B), IL‐4 (C), IL‐10 (D). ELISA detection of MDA (E), SOD (F), GPx (G), GR (H), CAT (I), and T‐AOC (J). N = 5/group. Ctl, control group; SD, acute sleep deprivation group. * p < 0.05, ** p < 0.01.

    Journal: Brain and Behavior

    Article Title: Ouabain Relieves Sleep Deprivation–Induced Anxiety‐Like Behavior in Mice by Suppressing Hippocampal Neuroinflammation and Oxidative Stress

    doi: 10.1002/brb3.71629

    Figure Lengend Snippet: Ouabain's antioxidant and anti‐inflammatory effects depends on the Src/p38 MAPK/NF‐κB pathway. Hippocampal levels of TNF‐α (A), IL‐1β (B), IL‐4 (C), IL‐10 (D). ELISA detection of MDA (E), SOD (F), GPx (G), GR (H), CAT (I), and T‐AOC (J). N = 5/group. Ctl, control group; SD, acute sleep deprivation group. * p < 0.05, ** p < 0.01.

    Article Snippet: Ouabain (≥ 98% purity; CAS 11018‐89‐6; Sigma, St. Louis, USA), SU6656 (HY‐B0789; MedChemExpress, USA), anisomycin (HY‐18982; MedChemExpress), and TNF‐α (HY‐P1860; MedChemExpress) were dissolved in DMSO and then diluted with normal saline to appropriate concentrations before use.

    Techniques: Enzyme-linked Immunosorbent Assay, Control

    Treprostinil promotes endothelial cell survival and viability (A) TUNEL staining showed that treprostinil significantly inhibited the apoptosis of human umbilical vein endothelial cells (HUVECs) induced by tumor necrosis factor-α ( n = 3 biological samples per group). Scale bars, 50 μm (B–D) CCK8 and qPCR analyses suggested that treprostinil promoted cell viability and reduced inflammation in HUVECs ( n = 6 biological samples per group). Two-tailed unpaired Student’s t test was used to calculate statistical significance. Data are represented as mean ± SEM. ∗ represents p < 0.05, ∗∗ represents p < 0.01, and ∗∗∗ represents p < 0.001.

    Journal: iScience

    Article Title: Development of immune-derived molecular markers for coronary heart disease via multimachine learning

    doi: 10.1016/j.isci.2026.114853

    Figure Lengend Snippet: Treprostinil promotes endothelial cell survival and viability (A) TUNEL staining showed that treprostinil significantly inhibited the apoptosis of human umbilical vein endothelial cells (HUVECs) induced by tumor necrosis factor-α ( n = 3 biological samples per group). Scale bars, 50 μm (B–D) CCK8 and qPCR analyses suggested that treprostinil promoted cell viability and reduced inflammation in HUVECs ( n = 6 biological samples per group). Two-tailed unpaired Student’s t test was used to calculate statistical significance. Data are represented as mean ± SEM. ∗ represents p < 0.05, ∗∗ represents p < 0.01, and ∗∗∗ represents p < 0.001.

    Article Snippet: Tumor necrosis factor-α , MedChemExpress , HY-P1860.

    Techniques: TUNEL Assay, Staining, Two Tailed Test