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ogp  (MedChemExpress)


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    MedChemExpress ogp
    Proliferation and cytotoxic effects from <t>OGP</t> treatment <t>on</t> <t>hPDLSCs.</t> (A) Schematic experiment and (B) proliferation assay for mitogenic activity using alamarBlue™ assay were presented. (C) Live cells stained with calcein-AM and dead cells stained with propidium iodide were illustrated in green and red, respectively. Bars on proliferation assay result indicated the significant difference ( p <0.05).
    Ogp, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy-p1563/Osteogenic+Growth+Peptide%2C+OGP/pmc09304736-67-3-7
    Average 90 stars, based on 1 article reviews
    ogp - by Bioz Stars, 2026-10
    90/100 stars

    Images

    1) Product Images from "Osteogenic growth peptide enhances osteogenic differentiation of human periodontal ligament stem cells"

    Article Title: Osteogenic growth peptide enhances osteogenic differentiation of human periodontal ligament stem cells

    Journal: Heliyon

    doi: 10.1016/j.heliyon.2022.e09936

    Proliferation and cytotoxic effects from OGP treatment on hPDLSCs. (A) Schematic experiment and (B) proliferation assay for mitogenic activity using alamarBlue™ assay were presented. (C) Live cells stained with calcein-AM and dead cells stained with propidium iodide were illustrated in green and red, respectively. Bars on proliferation assay result indicated the significant difference ( p <0.05).
    Figure Legend Snippet: Proliferation and cytotoxic effects from OGP treatment on hPDLSCs. (A) Schematic experiment and (B) proliferation assay for mitogenic activity using alamarBlue™ assay were presented. (C) Live cells stained with calcein-AM and dead cells stained with propidium iodide were illustrated in green and red, respectively. Bars on proliferation assay result indicated the significant difference ( p <0.05).

    Techniques Used: Proliferation Assay, Activity Assay, Alamar Blue Assay, Staining

    Osteogenic differentiation effects of OGP on hPDLSCs. (A) Schematic experiment of OGP treatment on hPDLSCs toward osteogenic lineage. (B) The ALP activity, (C) osteogenic-related marker expression, (D) mineral deposition, and (E) Alizarin Red S staining quantification were presented. Bars on ALP activity results and Alizarin Red S staining quantification and asterisks on gene expression results indicated the statistically significant difference between OM and other groups ( p <0.05).
    Figure Legend Snippet: Osteogenic differentiation effects of OGP on hPDLSCs. (A) Schematic experiment of OGP treatment on hPDLSCs toward osteogenic lineage. (B) The ALP activity, (C) osteogenic-related marker expression, (D) mineral deposition, and (E) Alizarin Red S staining quantification were presented. Bars on ALP activity results and Alizarin Red S staining quantification and asterisks on gene expression results indicated the statistically significant difference between OM and other groups ( p <0.05).

    Techniques Used: Activity Assay, Marker, Expressing, Staining, Gene Expression

    Osteogenic-regulated signaling pathway screening of OGP treatment on hPDLSCs toward osteogenic lineage. (A) Schematic experiment of OGP treatment on hPDLSCs to evaluate osteogenic-related pathways was indicated. (B) Bone morphogenetic protein (BMP), (C) Hedgehog, (D) Notch, (E) transforming growth factor-beta (TGF-β), and (F) Wnt signalings related gene expression were presented. Asterisks beside the dot of experimental group on gene expression results indicated the significant difference between OM and other groups ( p <0.05).
    Figure Legend Snippet: Osteogenic-regulated signaling pathway screening of OGP treatment on hPDLSCs toward osteogenic lineage. (A) Schematic experiment of OGP treatment on hPDLSCs to evaluate osteogenic-related pathways was indicated. (B) Bone morphogenetic protein (BMP), (C) Hedgehog, (D) Notch, (E) transforming growth factor-beta (TGF-β), and (F) Wnt signalings related gene expression were presented. Asterisks beside the dot of experimental group on gene expression results indicated the significant difference between OM and other groups ( p <0.05).

    Techniques Used: Gene Expression

    Effect of SB-431542 on OGP-induced osteogenic differentiation in hPDLSCs. (A) Schematic experiment was illustrated. (B) The ALP activity, (C) osteogenic-related marker expression, (D) mineral deposition, and (E) Alizarin Red S staining quantification were presented. Bars and asterisks indicated the significant difference between OM and other groups ( p <0.05).
    Figure Legend Snippet: Effect of SB-431542 on OGP-induced osteogenic differentiation in hPDLSCs. (A) Schematic experiment was illustrated. (B) The ALP activity, (C) osteogenic-related marker expression, (D) mineral deposition, and (E) Alizarin Red S staining quantification were presented. Bars and asterisks indicated the significant difference between OM and other groups ( p <0.05).

    Techniques Used: Activity Assay, Marker, Expressing, Staining

    Related Articles

    Cell Culture:

    Article Title: Osteogenic growth peptide enhances osteogenic differentiation of human periodontal ligament stem cells
    Article Snippet: .. For OGP treatment, OGP was purchased from MedChemExpress (Cat. No. HY-P1563, USA). hPDLSCs were cultured with OGP supplemented in culture medium at concentrations of 0.01, 0.1, 1, 10, and 100 nM according to previous publication ( ). .. In some experiments, cells were treated with a specific inhibitor of TGF-β, SB-431542 (Sigma-Aldrich, USA) at the concentration of 4 μM.



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    Proliferation and cytotoxic effects from <t>OGP</t> treatment <t>on</t> <t>hPDLSCs.</t> (A) Schematic experiment and (B) proliferation assay for mitogenic activity using alamarBlue™ assay were presented. (C) Live cells stained with calcein-AM and dead cells stained with propidium iodide were illustrated in green and red, respectively. Bars on proliferation assay result indicated the significant difference ( p <0.05).
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    Proliferation and cytotoxic effects from <t>OGP</t> treatment <t>on</t> <t>hPDLSCs.</t> (A) Schematic experiment and (B) proliferation assay for mitogenic activity using alamarBlue™ assay were presented. (C) Live cells stained with calcein-AM and dead cells stained with propidium iodide were illustrated in green and red, respectively. Bars on proliferation assay result indicated the significant difference ( p <0.05).
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    Image Search Results


    Proliferation and cytotoxic effects from OGP treatment on hPDLSCs. (A) Schematic experiment and (B) proliferation assay for mitogenic activity using alamarBlue™ assay were presented. (C) Live cells stained with calcein-AM and dead cells stained with propidium iodide were illustrated in green and red, respectively. Bars on proliferation assay result indicated the significant difference ( p <0.05).

    Journal: Heliyon

    Article Title: Osteogenic growth peptide enhances osteogenic differentiation of human periodontal ligament stem cells

    doi: 10.1016/j.heliyon.2022.e09936

    Figure Lengend Snippet: Proliferation and cytotoxic effects from OGP treatment on hPDLSCs. (A) Schematic experiment and (B) proliferation assay for mitogenic activity using alamarBlue™ assay were presented. (C) Live cells stained with calcein-AM and dead cells stained with propidium iodide were illustrated in green and red, respectively. Bars on proliferation assay result indicated the significant difference ( p <0.05).

    Article Snippet: For OGP treatment, OGP was purchased from MedChemExpress (Cat. No. HY-P1563, USA). hPDLSCs were cultured with OGP supplemented in culture medium at concentrations of 0.01, 0.1, 1, 10, and 100 nM according to previous publication ( ).

    Techniques: Proliferation Assay, Activity Assay, Alamar Blue Assay, Staining

    Osteogenic differentiation effects of OGP on hPDLSCs. (A) Schematic experiment of OGP treatment on hPDLSCs toward osteogenic lineage. (B) The ALP activity, (C) osteogenic-related marker expression, (D) mineral deposition, and (E) Alizarin Red S staining quantification were presented. Bars on ALP activity results and Alizarin Red S staining quantification and asterisks on gene expression results indicated the statistically significant difference between OM and other groups ( p <0.05).

    Journal: Heliyon

    Article Title: Osteogenic growth peptide enhances osteogenic differentiation of human periodontal ligament stem cells

    doi: 10.1016/j.heliyon.2022.e09936

    Figure Lengend Snippet: Osteogenic differentiation effects of OGP on hPDLSCs. (A) Schematic experiment of OGP treatment on hPDLSCs toward osteogenic lineage. (B) The ALP activity, (C) osteogenic-related marker expression, (D) mineral deposition, and (E) Alizarin Red S staining quantification were presented. Bars on ALP activity results and Alizarin Red S staining quantification and asterisks on gene expression results indicated the statistically significant difference between OM and other groups ( p <0.05).

    Article Snippet: For OGP treatment, OGP was purchased from MedChemExpress (Cat. No. HY-P1563, USA). hPDLSCs were cultured with OGP supplemented in culture medium at concentrations of 0.01, 0.1, 1, 10, and 100 nM according to previous publication ( ).

    Techniques: Activity Assay, Marker, Expressing, Staining, Gene Expression

    Osteogenic-regulated signaling pathway screening of OGP treatment on hPDLSCs toward osteogenic lineage. (A) Schematic experiment of OGP treatment on hPDLSCs to evaluate osteogenic-related pathways was indicated. (B) Bone morphogenetic protein (BMP), (C) Hedgehog, (D) Notch, (E) transforming growth factor-beta (TGF-β), and (F) Wnt signalings related gene expression were presented. Asterisks beside the dot of experimental group on gene expression results indicated the significant difference between OM and other groups ( p <0.05).

    Journal: Heliyon

    Article Title: Osteogenic growth peptide enhances osteogenic differentiation of human periodontal ligament stem cells

    doi: 10.1016/j.heliyon.2022.e09936

    Figure Lengend Snippet: Osteogenic-regulated signaling pathway screening of OGP treatment on hPDLSCs toward osteogenic lineage. (A) Schematic experiment of OGP treatment on hPDLSCs to evaluate osteogenic-related pathways was indicated. (B) Bone morphogenetic protein (BMP), (C) Hedgehog, (D) Notch, (E) transforming growth factor-beta (TGF-β), and (F) Wnt signalings related gene expression were presented. Asterisks beside the dot of experimental group on gene expression results indicated the significant difference between OM and other groups ( p <0.05).

    Article Snippet: For OGP treatment, OGP was purchased from MedChemExpress (Cat. No. HY-P1563, USA). hPDLSCs were cultured with OGP supplemented in culture medium at concentrations of 0.01, 0.1, 1, 10, and 100 nM according to previous publication ( ).

    Techniques: Gene Expression

    Effect of SB-431542 on OGP-induced osteogenic differentiation in hPDLSCs. (A) Schematic experiment was illustrated. (B) The ALP activity, (C) osteogenic-related marker expression, (D) mineral deposition, and (E) Alizarin Red S staining quantification were presented. Bars and asterisks indicated the significant difference between OM and other groups ( p <0.05).

    Journal: Heliyon

    Article Title: Osteogenic growth peptide enhances osteogenic differentiation of human periodontal ligament stem cells

    doi: 10.1016/j.heliyon.2022.e09936

    Figure Lengend Snippet: Effect of SB-431542 on OGP-induced osteogenic differentiation in hPDLSCs. (A) Schematic experiment was illustrated. (B) The ALP activity, (C) osteogenic-related marker expression, (D) mineral deposition, and (E) Alizarin Red S staining quantification were presented. Bars and asterisks indicated the significant difference between OM and other groups ( p <0.05).

    Article Snippet: For OGP treatment, OGP was purchased from MedChemExpress (Cat. No. HY-P1563, USA). hPDLSCs were cultured with OGP supplemented in culture medium at concentrations of 0.01, 0.1, 1, 10, and 100 nM according to previous publication ( ).

    Techniques: Activity Assay, Marker, Expressing, Staining