high dose ang iv (MedChemExpress)
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high dose ang iv
High Dose Ang Iv, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 90/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hy-p1515a/Angiotensin+II+(3-8)%2C+human/pmc08419053-42-3-15
Average 90 stars, based on 2 article reviews
High Dose Ang Iv, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 90/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hy-p1515a/Angiotensin+II+(3-8)%2C+human/pmc08419053-42-3-15
Average 90 stars, based on 2 article reviews
high dose ang iv - by Bioz Stars,
2026-10
90/100 stars
Images
1) Product Images from "Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis"
Article Title: Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis
Journal: Theranostics
doi: 10.7150/thno.48561
Figure Legend Snippet: Effects of Ang IV on left ventricular function and dimension in 5 groups of mice of the first part in vivo experiment
Techniques Used: In Vivo
Figure Legend Snippet: Transcriptome profiles of the myocardium in 3 groups of mice and effects of Ang IV on the expressions of autophagy-associated proteins in the myocardium of 5 groups of mice. (A) Hierarchical clustering heatmap to identify differentially expressed genes in NC and DM groups of mice. (B) The top 20 biological processes from the GO enrichment analysis of differentially expressed genes in NC and DM groups of mice. (C) The top 10 gene pathways from KEGG pathway enrichment analysis of differentially expressed genes in NC and DM groups of mice. (D) Hierarchical clustering heatmap to identify differentially expressed genes in DM and DM+high-dose Ang IV groups of mice. (E) The top 20 gene pathways from KEGG pathway enrichment analysis of differentially expressed genes in DM and DM+high-dose Ang IV groups of mice. n=4 per group. (F) Representative Western blot images of LC3, Beclin1, p62, pFoxO1 and FoxO1 protein expression in the myocardium of the 5 groups of mice. (G) Quantification of LC3-II, Beclin1, p62 and pFoxO1/FoxO1 protein expression in the myocardium of the 5 groups of mice. n=5 per group. Ang IV: angiotensin IV; DM: diabetes mellitus; NC: normal control. * p < 0.05, ** p < 0.01, *** p < 0.001.
Techniques Used: Western Blot, Expressing, Control
Figure Legend Snippet: Effects of AT 4 R and FoxO1 on left ventricular function and expressions of fibrosis-, apoptosis- and autophagy-associated proteins in the myocardium of 5 groups of mice. (A) Representative echocardiographic images in 5 groups of mice. (A1) Two-dimensional echocardiograms showing left ventricular long-axis views and scale bar in mm on the right; (A2) M-mode echocardiograms showing left ventricular dimensions, scale bar in mm on the right, and time stamp in seconds at the bottom; (A3) Pulse-wave Doppler echocardiograms depicting mitral inflow velocities, scale bar in mm/s on the right, and time stamp in seconds at the bottom; (A4) Tissue Doppler echocardiograms displaying mitral annular velocities, scale bar in mm/s on the right, and time stamp in seconds at the bottom. n≥8 per group. (B) Representative Western blot images of Col I, Col III, TGF-β1, Bax, Bcl-2 and Cl-caspase3 protein expressions in the myocardium of 5 groups of mice. (C-G) Quantifications of Col I, Col III, TGF-β1, Bax/Bcl-2 and Cl-caspase3 protein expressions in the myocardium of 5 groups of mice. (H) Representative Western blot images of LC3, Beclin1 and p62 expressions in the myocardium of 5 groups of mice. (I-K) Quantification of LC3-II, Beclin1 and p62 expressions in the myocardium of 5 groups of mice. After DM was successfully induced, mice were divided into the following 5 groups: DM group that received an infusion of vehicle alone, Ang IV group that received an infusion of high-dose Ang IV, Ang IV+divalinal group that received an infusion of high-dose Ang IV plus AT 4 R antagonist divalinal, AS group that received an infusion of FoxO1 inhibitor AS1842856, and Ang IV+AS group that received an infusion of Ang IV plus AS1842856. n=5 per group. Ang IV: angiotensin IV; AS: AS1842856; Cl-caspase3: cleaved caspase 3; Col I: collagen I; Col III: collagen III. * p < 0.05, ** p < 0.01, *** p < 0.001.
Techniques Used: Western Blot
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Low-, medium-, or high-dose Ang IV (0.72 mg/kg/day, 1.44 mg/kg/day, and 2.88 mg/kg/day, respectively; HY-P1515A, Article Title: Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis Article Snippet: In the NC group, mice were intraperitoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days.In the NC group, mice were intraperitoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days.. Low-, medium-, or Enzyme-linked Immunosorbent Assay:Article Title: Aptamer-assisted two-point immobilized agonist-bound angiotensin II type 1 receptor for a second-site modulator discovery Article Snippet: DNA Polymerase with Standard Taq Buffer , New England Biolabs , M0273L. .. Ang II (3–8) , Article Title: Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis Article Snippet: eritoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days. Low-, medium-, or high-dose Ang IV (0.72 mg/kg/day, 1.44 mg/kg/day, and 2.88 mg/kg/day, respectively; HY-P1515A, Article Title: Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis Article Snippet: In the NC group, mice were intraperitoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days.In the NC group, mice were intraperitoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days.. Low-, medium-, or Software:Article Title: Aptamer-assisted two-point immobilized agonist-bound angiotensin II type 1 receptor for a second-site modulator discovery Article Snippet: DNA Polymerase with Standard Taq Buffer , New England Biolabs , M0273L. .. Ang II (3–8) , Article Title: Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis Article Snippet: eritoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days. Low-, medium-, or high-dose Ang IV (0.72 mg/kg/day, 1.44 mg/kg/day, and 2.88 mg/kg/day, respectively; HY-P1515A, Article Title: Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis Article Snippet: In the NC group, mice were intraperitoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days.In the NC group, mice were intraperitoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days.. Low-, medium-, or In Vivo:Article Title: Aptamer-assisted two-point immobilized agonist-bound angiotensin II type 1 receptor for a second-site modulator discovery Article Snippet: DNA Polymerase with Standard Taq Buffer , New England Biolabs , M0273L. .. Ang II (3–8) , Article Title: Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis Article Snippet: eritoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days. Low-, medium-, or high-dose Ang IV (0.72 mg/kg/day, 1.44 mg/kg/day, and 2.88 mg/kg/day, respectively; HY-P1515A, Article Title: Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis Article Snippet: In the NC group, mice were intraperitoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days.In the NC group, mice were intraperitoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days.. Low-, medium-, or Western Blot:Article Title: Aptamer-assisted two-point immobilized agonist-bound angiotensin II type 1 receptor for a second-site modulator discovery Article Snippet: DNA Polymerase with Standard Taq Buffer , New England Biolabs , M0273L. .. Ang II (3–8) , Article Title: Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis Article Snippet: eritoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days. Low-, medium-, or high-dose Ang IV (0.72 mg/kg/day, 1.44 mg/kg/day, and 2.88 mg/kg/day, respectively; HY-P1515A, Article Title: Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis Article Snippet: In the NC group, mice were intraperitoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days.In the NC group, mice were intraperitoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days.. Low-, medium-, or Expressing:Article Title: Aptamer-assisted two-point immobilized agonist-bound angiotensin II type 1 receptor for a second-site modulator discovery Article Snippet: DNA Polymerase with Standard Taq Buffer , New England Biolabs , M0273L. .. Ang II (3–8) , Article Title: Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis Article Snippet: eritoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days. Low-, medium-, or high-dose Ang IV (0.72 mg/kg/day, 1.44 mg/kg/day, and 2.88 mg/kg/day, respectively; HY-P1515A, Article Title: Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis Article Snippet: In the NC group, mice were intraperitoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days.In the NC group, mice were intraperitoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days.. Low-, medium-, or Control:Article Title: Aptamer-assisted two-point immobilized agonist-bound angiotensin II type 1 receptor for a second-site modulator discovery Article Snippet: DNA Polymerase with Standard Taq Buffer , New England Biolabs , M0273L. .. Ang II (3–8) , Article Title: Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis Article Snippet: eritoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days. Low-, medium-, or high-dose Ang IV (0.72 mg/kg/day, 1.44 mg/kg/day, and 2.88 mg/kg/day, respectively; HY-P1515A, Article Title: Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis Article Snippet: In the NC group, mice were intraperitoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days.In the NC group, mice were intraperitoneally injected with vehicle (0.1 mL of citrate buffer, pH 4.5) daily for 5 days.. Low-, medium-, or |
