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p1061  (MedChemExpress)


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    Structured Review

    MedChemExpress p1061
    P1061, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 42 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy-p1061/Colivelin/pmc13187529-28-4-2
    Average 95 stars, based on 42 article reviews
    p1061 - by Bioz Stars, 2026-10
    95/100 stars

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    Related Articles

    Cell Culture:

    Article Title: STAT3 Inhibitor Suppresses CCL2-dependent Recruitment and M2 Polarization of Tumor-associated Macrophages to Enhance Antitumor Immunity in Ovarian Cancer.
    Article Snippet: Ovarian cancer is a common malignant tumor that severely compromises patient health.. STAT3 inhibitor has been widely explored and exhibits therapeutic impacts in diverse cancers.. However, the regulatory influences of STAT3 inhibitor on antitumor immunity in ovarian cancer progression need further explorations.

    CCK-8 Assay:

    Article Title: TTPAL inhibits the progression of breast cancer and reprograms tumor-associated macrophages by inhibiting JAK2/STAT3 signaling pathway
    Article Snippet: .. The culture medium was replaced with medium containing 18 μΜ concentrations of Colivelin (HY-P1061, MCE) for 6 h. Cell growth was monitored by CCK-8 assay according to the manufacturer’s instruction (CK04, Dojindo Molecular Technologies). ..

    other:

    Article Title: Astragaloside IV attenuates oxidative stress-associated mitophagy-dependent ferroptosis in peritoneal mesothelial cells via suppression of STAT3 signaling
    Article Snippet: The chemicals methylglyoxal (MGO; HY-w020014), S3I-201 (HY-15146), colivlin (HY-P1061), liproxstatin-1 (HY-12726), Carbonyl cyanide m-chlorophenylhydrazone (CCCP; HY-100941), erastin (HY-15763), N-acetylcysteine (NAC; HY-B0215), and mitochondrial division inhibitor 1 (Mdivi-1; HY-15886) were purchased from MedChemExpress (Monmouth Junction, NJ, USA).

    Cell Function Assay:

    Article Title: METTL1-Mediated m7G Modification of GINS2 mRNA Activates STAT3 to Drive Esophageal Squamous Cell Carcinoma Progression.
    Article Snippet: Background: METTL1mediated m7G modification plays a procancer role in various malignant tumors, but whether it promotes the progression of esophageal squamous cell carcinoma (ESCC) by regulating the DNA replication factor GINS2 and tumorassociated macrophage polarization remains unclear.. Methods: The expression and function of GINS2 were examined through in vitro and in vivo experiments.. RIP, MeRIP, and RNA stability assays were used to validate the regulatory effect of METTL1 on GINS2 modification.

    Transfection:

    Article Title: METTL1-Mediated m7G Modification of GINS2 mRNA Activates STAT3 to Drive Esophageal Squamous Cell Carcinoma Progression.
    Article Snippet: Background: METTL1mediated m7G modification plays a procancer role in various malignant tumors, but whether it promotes the progression of esophageal squamous cell carcinoma (ESCC) by regulating the DNA replication factor GINS2 and tumorassociated macrophage polarization remains unclear.. Methods: The expression and function of GINS2 were examined through in vitro and in vivo experiments.. RIP, MeRIP, and RNA stability assays were used to validate the regulatory effect of METTL1 on GINS2 modification.

    Negative Control:

    Article Title: METTL1-Mediated m7G Modification of GINS2 mRNA Activates STAT3 to Drive Esophageal Squamous Cell Carcinoma Progression.
    Article Snippet: Background: METTL1mediated m7G modification plays a procancer role in various malignant tumors, but whether it promotes the progression of esophageal squamous cell carcinoma (ESCC) by regulating the DNA replication factor GINS2 and tumorassociated macrophage polarization remains unclear.. Methods: The expression and function of GINS2 were examined through in vitro and in vivo experiments.. RIP, MeRIP, and RNA stability assays were used to validate the regulatory effect of METTL1 on GINS2 modification.



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