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nmol shu 9119  (MedChemExpress)


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    Structured Review

    MedChemExpress nmol shu 9119
    Nmol Shu 9119, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy-p0227/SHU+9119/pmc11244552-265-52-63
    Average 94 stars, based on 5 article reviews
    nmol shu 9119 - by Bioz Stars, 2026-10
    94/100 stars

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    Related Articles

    other:

    Article Title: Glucagon-like Peptide-2 Acts Partially Through Central GLP-2R and MC4R in Mobilizing Stored Lipids from the Intestine.
    Article Snippet: SHU9119, an MC4R antagonist, was obtained from MedchemExpress (Monmouth Junction, NJ, USA).

    Article Title: Glucagon-like Peptide-2 Acts Partially Through Central GLP-2R and MC4R in Mobilizing Stored Lipids from the Intestine
    Article Snippet: SHU9119, an MC4R antagonist, was obtained from MedchemExpress (Monmouth Junction, NJ, USA).

    Article Title: The tongue-brain axis mediates a hidden amino acid appetite
    Article Snippet: The drugs including GABAbR antagonist saclofen (0.1 μg/μL, HY-100813 MCE) and CGP55845 hydrochloride (8 ng/μL, HY-103516, MCE, China), GABAbR agonist baclofen (0.04 μg/μL, HY-B0007 MCE), GABAaR antagonist bicuculline (2.5 μM, HY-N0219, MCE), MC3R/4R antagonist SHU 9119 (1 nM, HY-P0227, MCE), NPY1R antagonist BIBO3304 (0.25 mM, HY-107725, MCE), NPY2R antagonist BIIE-0246 (0.25 mM, HY-101986), NPY5R antagonist CGP71683 hydrochloride(15 nM, HY-107723, MCE) and leucine (1.1μg/μL in 10% DMSO).

    Injection:

    Article Title: Paraventricular hypothalamic RUVBL2 neurons suppress appetite by enhancing excitatory synaptic transmission in distinct neurocircuits
    Article Snippet: .. At night time, mice were first intraperitoneally injected with SHU9119 (0.5 mg/kg, MCE, HY-P0227), followed by optical activation of the axon terminals of PVH RUVBL2 neurons in the ARC using a 465-nm blue laser light for 6 h when the laser light was switched on every other 30 min. ..

    Activation Assay:

    Article Title: Paraventricular hypothalamic RUVBL2 neurons suppress appetite by enhancing excitatory synaptic transmission in distinct neurocircuits
    Article Snippet: .. At night time, mice were first intraperitoneally injected with SHU9119 (0.5 mg/kg, MCE, HY-P0227), followed by optical activation of the axon terminals of PVH RUVBL2 neurons in the ARC using a 465-nm blue laser light for 6 h when the laser light was switched on every other 30 min. ..

    Control:

    Article Title: Mast cell promotes obesity by activating microglia in hypothalamus
    Article Snippet: For cromolyn sodium treatment, HFD-fed mice implanted with a guide cannula targeting the lateral ventricle were administered cromolyn sodium (MCE, HY-B0320A) intracerebroventricularly (i.c.v.) daily at a dose of 10 μg, immediately before the light was turned off. .. For administration of the SHU9119 (MCE, HY-P0227), lateral ventricle-cannulated HFD mice were briefly fasted, and received i.c.v. administration of SHU9119 (1μg,1 μL) or 0.9% NaCl as a control. ..



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