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neurokinin a  (MedChemExpress)


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    Structured Review

    MedChemExpress neurokinin a
    Neurokinin A, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy-p0197/Neurokinin+A/ppr0547573-132-100-103
    Average 93 stars, based on 2 article reviews
    neurokinin a - by Bioz Stars, 2026-10
    93/100 stars

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    Article Title: The enhancing effect of 5-HT on phasic contractions of human isolated distal ureter and possible mediating mechanisms
    Article Snippet: D a ta m ay b e p re li m in a ry . onist), SB-224289 hydrochloride (MCE, HT1B selective antagonist), LY310762(MCE, HT1Dselective antagonist), volinanserin (MCE, 5-HT2Aselective antagonist), RS-127445(MCE, 5-HT2B selective antagonist), SB242084 (MCE, 5-HT2C selective antagonist), ketanserin (MCE, 5-HT2 non-selective antagonist), ondansetron hydrochloride dehydrate (Sigma-Aldrich, 5-HT3 selective antagonist), GR113808 (Tocris, 5-HT4 selective antagonist), SB 699551 (Sigma-Aldrich, 5-HT5 selective antagonist), SB-399885 hydrochloride (Sigma-Aldrich, 5-HT6 selective antagonist), SB-269970 hydrochloride (MCE, 5-HT7 selective antagonist), 25CN-NBOH hydrochloride (Efebio, 5-HT2A selective agonist), vabicaserin hydrochloride (MCE, 5-HT2Cselective agonist), tamsulosin (MCE, α1-adrenergic receptor antagonist), guanethidine sulfate (MCE, adrenergic neurotransmission blocker), Men10376 (MCE, NK-2 receptor antagonist), neurokinin A (NKA, MCE), and tetrodotoxin (TTX, Sigma-Aldrich).

    Article Title: TRPM3 channel activation inhibits contraction of the isolated human ureter via CGRP released from sensory nerves.
    Article Snippet: Aims: Sensory nerve activation modulates ureteral contractility by releasing neuropeptides including CGRP and neurokinin A (NKA).. TRPM3 is a recently discovered thermosensitive channel expressed in nociceptive sensory neurons, and plays a key role in heat nociception and chronic pain.. The aim of this study is to examine the role of TRPM3 activation in human ureter motility.

    Article Title: The enhancing effect of 5-HT on phasic contractions of human isolated distal ureter and the mechanisms mediating these effects.
    Article Snippet: The chemicals used in this study included 5-HT hydrochloride (MCE), p-MPPI (a 5-HT1A receptor-selective antagonist; MCE), SB224289 hydrochloride (an HT1B receptor-selective antagonist; MCE), LY310762 (an HT1D receptor-selective antagonist; MCE), volinanserin (a 5-HT2A receptor-selective antagonist; MCE), RS-127445 (a 5-HT2B receptor-selective antagonist; MCE), SB242084 (a 5-HT2C receptorselective antagonist; MCE), ketanserin (a 5-HT2 non-selective antagonist; MCE), ondansetron hydrochloride dehydrate (a 5-HT3 receptorselective antagonist; Sigma-Aldrich), GR113808 (a 5-HT4 receptorselective antagonist; Tocris), SB699551 (5-HT5 receptor-selective antagonist; Sigma-Aldrich), SB399885 hydrochloride (a 5-HT6 receptor-selective antagonist; Sigma-Aldrich), SB269970 hydrochloride (a 5-HT7 receptor-selective antagonist; MCE), 25CN–NBOH hydrochloride (a 5-HT2A receptor-selective agonist; Efebio), vabicaserin hydrochloride (a 5-HT2C receptor-selective agonist; MCE), tamsulosin (an α1adrenergic receptor antagonist; MCE), guanethidine sulfate (an adrenergic neurotransmission blocker; MCE), Men10376 (an NK-2 receptor antagonist; MCE), NKA (MCE), and tetrodotoxin (TTX; Sigma-Aldrich).

    Article Title: Activation of TRPM8 channel inhibits contraction of the isolated human ureter.
    Article Snippet: Funding information National Natural Science Funds of China, Grant/Award Number: 82070783; Natural Science Funds of Shandong Province, Grant/Award Number: ZR2020MH083 Abstract Aims: The transient receptor potential melastin‐8 (TRPM8) channel is a “cooling” receptor expressed in primary sensory neurons and can be activated by compounds like menthol or icilin.. TRPM8 is involved in the regulation of urinary bladder sensory function and contraction, but the role of TRPM8 in the ureter, particularly in the human ureter, is poorly understood.. The aim of this study is to examine the effects of TRPM8 activation on human ureter contraction.



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