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Injection, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hy-n9388/Andrograpanin/pm42114306-71-2-8
Average 94 stars, based on 3 article reviews
Injection, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hy-n9388/Andrograpanin/pm42114306-71-2-8
Average 94 stars, based on 3 article reviews
injection - by Bioz Stars,
2026-10
94/100 stars
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other:Article Title: Discovery of multitarget-directed small molecule inhibitors from Andrographis paniculata for Nipah virus disease therapy: Molecular docking, molecular dynamics simulation and ADME-Tox profiling Article Snippet: AGNN has been reported as a hydrolysate anti-inflammatory drug with potential to down-regulate p38 MAPKs signalling pathway, and useful as Article Title: Harmonizing international quality standards for Andrographis paniculata: A comparative analysis of content determination methods across pharmacopeias. Article Snippet: The quality standards for Andrographis paniculata, a widely used medicinal herb, exhibited significant variations across different pharmacopeias.. In this study, we compared the HPLC content determination methods and total lactone content of A. paniculata samples from different regions, as specified in the Chinese (CP), United States (USP), European (EP), Thai (TP), and Indian pharmacopeias (IP), as well as the Hong Kong Chinese Materia Medica Standards (HK).. We aimed to assess the differences and similarities among these pharmacopeias and harmonized international quality standards for A. paniculata. Article Title: Andrograpanin attenuates secondary neuroinflammation after spinal cord injury by modulating microglial glycolysis via HIF-1α. Article Snippet: Spinal cord injury (SCI), a devastating central nervous system disorder, often leads to persistent sensory, motor, and autonomic impairments that severely reduce quality of life.. Following SCI, a rapidly formed hypoxic microenvironment induces abnormal accumulation of hypoxia-inducible factor-1α (HIF-1α), whose sustained activation triggers excessive pro-inflammatory cascades and dysregulated glycolysis, thereby aggravating secondary neuronal injury.. In this study, we employed an integrated strategy combining network pharmacology, transcriptome sequencing, and in vivo and in vitro experiments to investigate the therapeutic potential of the Andrograpanin derivative Andrograpanin in SCI-induced secondary inflammation. |