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    MedChemExpress hi
    Hi, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 90/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy-n7059/Lactobionic+acid/pm30121004-7-57-153
    Average 90 stars, based on 4 article reviews
    hi - by Bioz Stars, 2026-10
    90/100 stars

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    Article Title: Analysis of driver injury severity in single-vehicle crashes on rural and urban roadways.
    Article Snippet: This study analyzes driver injury severities for single-vehicle crashes occurring in rural and urban areas using data collected in New Mexico from 2010 to 2011.. Nested logit models and mixed logit models are developed in order to account for the correlation between severity categories (No injury, Possible injury, Visible injury, Incapacitating injury and fatality) and individual heterogeneity among drivers.. Various factors, such as crash and environment characteristics, geometric features, and driver behavior are examined in this study.

    Article Title: Immobilized bioprocess for organic carbon and nitrogen removal
    Article Snippet: +886-2-3366-7427 b Department of Civil and Environmental Engineering , University of Utah , 110 South Central Campus Drive, 2068 MCE, Salt Lake City , UT , 84112 , USA c Department of Molecular Biosciences and Bioengineering , University of Hawaii at Manoa , Honolulu , Hawaii , 96822 , USA Published online: 31 Jan 2012.

    Article Title: Examining driver injury severity in intersection-related crashes using cluster analysis and hierarchical Bayesian models.
    Article Snippet: Traffic crashes are more likely to occur at intersections where the traffic environment is complicated.. In this study, a hybrid approach combining cluster analysis and hierarchical Bayesian models is developed to examine driver injury severity patterns in intersection-related crashes based on two-year crash data in New Mexico.. Three clusters are defined by K-means cluster analysis based on weather and roadway environmental conditions in order to reveal drivers’ risk compensation instability under diverse external environment.

    Bicinchoninic Acid Protein Assay:

    Article Title: Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis.
    Article Snippet: Compound Servicebio Cat#4583 Oil Red O Sigma-Aldrich Cat# 625 TMRM AAT Bioquest Cat# 22221 MitoTracker Red CMXRos YEASEN Cat# 40741ES50 Safranin O Sigma-Aldrich Cat#S2255 Rotenone Dalian Meilun Cat#MB7162 Digitonin Sigma-Aldrich Cat# D5628 Succinate Shanghai Maclin Cat# D822253 Pyruvate Sigma-Aldrich Cat# P2256 Glutamate Shanghai Maclin Cat#L810495 Malate Shanghai Maclin Cat#L813179 Ascorbate Sigma-Aldrich Cat#A7631 TMPD Shanghai Maclin Cat#T819055 ADP Shanghai Maclin Cat#A844435 AMP Sigma-Aldrich Cat#A2252 ATP Shanghai Maclin Cat#A800906 FCCP Dalian Meilun Cat#MB3642 (Continued on next page) e2 Cell Metabolism 31, 892–908.e1–e11, May 5, 2020 .. REAGENT or RESOURCE SOURCE IDENTIFIER Malonic acid Shanghai Maclin Cat#M813040 Antimycin A Dalian Meilun Cat# MB1384 Sodium azide Sigma-Aldrich Cat#S8032 Oligomycin Sigma-Aldrich Cat#O4876 Lactobionic acid Shanghai Maclin Cat#L812453 Taurine Sigma-Aldrich Cat#T0625 Valinomycin Shanghai Maclin Cat#V820378 Nigericin MedChemExpress Cat# HY-100381 BSA, essentially fatty acid free Equitech Bio Cat# BAH66-0100 Sodium palmitate Sigma-Aldrich Cat# P9767 Oleic acid Sigma-Aldrich Cat#O1008 DAPI Invitrogen Cat#S36939 Pazopanib Selleck Cat#S3012 ZM336372 Selleck Cat#S2720 SU1498 Selleck Cat#S6535 Tyrphostin AG 1296 Selleck Cat#S8024 Liver Perfusion Medium Thermo Fisher Scientific Cat#17701-038 Liver Digestion Medium Thermo Fisher Scientific Cat#17701-034 Pronase E Roche Cat#10165921001 Collagenase IV GIBCO Cat#17104019 DNase I Roche Cat#10104159001 Crystal violet Sinopharm Chemical Reagent Cat#71012314 Critical Commercial Assays BCA Protein assay kit Thermo Fisher Scientific Cat#23225 Transcriptor first-strand cDNA synthesis kit Roche Cat#04896866001 Triglyceride (TG) assay kit Wako Cat#290-63701 Cholesterol assay kit Wako Cat#294-65801 NEFA assay kit Wako Cat#294-63601 Triglyceride (TG) assay kit Solarbio Cat#BC0625 Mouse TNF ELISA kit Cloud-Clone Co. Cat#SEA133Mu Mouse MCP1(CCL2) ELISA kit Cloud-Clone Co. Cat#SEA087Mu Cell Counting Kit-8 assay kit Bimake Cat#B34304 Enhanced enzyme-labeled goat anti-rabbit IgG kit Beijing ZSGB-Bio Cat#PV-9001 3,30-Diaminobenzidine (DAB) substrate kit Beijing ZSGB-Bio Cat#ZLI-9018 RNA 6000 Nano kit Agilent Cat#5067-1511 MGIEasy RNA Library Prep Kit MGI Tech Co. Cat#1000006384 Deposited Data RNA-seq data of HFHC-fed mice This paper, NCBI SRA PRJNA613854 RNA-seq data of HFD-fed mice This paper, NCBI SRA PRJNA613938 RNA-seq data of HFHC-fed mice treated with CC and sorafenib This paper, NCBI SRA PRJNA613940 RNA-seq data of NASH monkeys This paper, NCBI SRA PRJNA614574 Proteomic data of NASH monkeys This paper, PRIDE PXD018256 Phospho-proteomic data of PA-treated L02 This paper, PRIDE PXD018214 Publicly available transcriptomic datasets from sorafenib treated HCC cell lines GEO database GSE43053, GSE73571, GSE96793, GSE102863 (Continued on next page) Cell Metabolism 31, 892–908.e1–e11, May 5, 2020 e3 .. REAGENT or RESOURCE SOURCE IDENTIFIER Experimental Models: Cell Lines Human: L02 (HL-7702) China Center for Type Culture Collection, Wuhan, China.

    cDNA Synthesis:

    Article Title: Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis.
    Article Snippet: Compound Servicebio Cat#4583 Oil Red O Sigma-Aldrich Cat# 625 TMRM AAT Bioquest Cat# 22221 MitoTracker Red CMXRos YEASEN Cat# 40741ES50 Safranin O Sigma-Aldrich Cat#S2255 Rotenone Dalian Meilun Cat#MB7162 Digitonin Sigma-Aldrich Cat# D5628 Succinate Shanghai Maclin Cat# D822253 Pyruvate Sigma-Aldrich Cat# P2256 Glutamate Shanghai Maclin Cat#L810495 Malate Shanghai Maclin Cat#L813179 Ascorbate Sigma-Aldrich Cat#A7631 TMPD Shanghai Maclin Cat#T819055 ADP Shanghai Maclin Cat#A844435 AMP Sigma-Aldrich Cat#A2252 ATP Shanghai Maclin Cat#A800906 FCCP Dalian Meilun Cat#MB3642 (Continued on next page) e2 Cell Metabolism 31, 892–908.e1–e11, May 5, 2020 .. REAGENT or RESOURCE SOURCE IDENTIFIER Malonic acid Shanghai Maclin Cat#M813040 Antimycin A Dalian Meilun Cat# MB1384 Sodium azide Sigma-Aldrich Cat#S8032 Oligomycin Sigma-Aldrich Cat#O4876 Lactobionic acid Shanghai Maclin Cat#L812453 Taurine Sigma-Aldrich Cat#T0625 Valinomycin Shanghai Maclin Cat#V820378 Nigericin MedChemExpress Cat# HY-100381 BSA, essentially fatty acid free Equitech Bio Cat# BAH66-0100 Sodium palmitate Sigma-Aldrich Cat# P9767 Oleic acid Sigma-Aldrich Cat#O1008 DAPI Invitrogen Cat#S36939 Pazopanib Selleck Cat#S3012 ZM336372 Selleck Cat#S2720 SU1498 Selleck Cat#S6535 Tyrphostin AG 1296 Selleck Cat#S8024 Liver Perfusion Medium Thermo Fisher Scientific Cat#17701-038 Liver Digestion Medium Thermo Fisher Scientific Cat#17701-034 Pronase E Roche Cat#10165921001 Collagenase IV GIBCO Cat#17104019 DNase I Roche Cat#10104159001 Crystal violet Sinopharm Chemical Reagent Cat#71012314 Critical Commercial Assays BCA Protein assay kit Thermo Fisher Scientific Cat#23225 Transcriptor first-strand cDNA synthesis kit Roche Cat#04896866001 Triglyceride (TG) assay kit Wako Cat#290-63701 Cholesterol assay kit Wako Cat#294-65801 NEFA assay kit Wako Cat#294-63601 Triglyceride (TG) assay kit Solarbio Cat#BC0625 Mouse TNF ELISA kit Cloud-Clone Co. Cat#SEA133Mu Mouse MCP1(CCL2) ELISA kit Cloud-Clone Co. Cat#SEA087Mu Cell Counting Kit-8 assay kit Bimake Cat#B34304 Enhanced enzyme-labeled goat anti-rabbit IgG kit Beijing ZSGB-Bio Cat#PV-9001 3,30-Diaminobenzidine (DAB) substrate kit Beijing ZSGB-Bio Cat#ZLI-9018 RNA 6000 Nano kit Agilent Cat#5067-1511 MGIEasy RNA Library Prep Kit MGI Tech Co. Cat#1000006384 Deposited Data RNA-seq data of HFHC-fed mice This paper, NCBI SRA PRJNA613854 RNA-seq data of HFD-fed mice This paper, NCBI SRA PRJNA613938 RNA-seq data of HFHC-fed mice treated with CC and sorafenib This paper, NCBI SRA PRJNA613940 RNA-seq data of NASH monkeys This paper, NCBI SRA PRJNA614574 Proteomic data of NASH monkeys This paper, PRIDE PXD018256 Phospho-proteomic data of PA-treated L02 This paper, PRIDE PXD018214 Publicly available transcriptomic datasets from sorafenib treated HCC cell lines GEO database GSE43053, GSE73571, GSE96793, GSE102863 (Continued on next page) Cell Metabolism 31, 892–908.e1–e11, May 5, 2020 e3 .. REAGENT or RESOURCE SOURCE IDENTIFIER Experimental Models: Cell Lines Human: L02 (HL-7702) China Center for Type Culture Collection, Wuhan, China.

    Cholesterol Assay:

    Article Title: Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis.
    Article Snippet: Compound Servicebio Cat#4583 Oil Red O Sigma-Aldrich Cat# 625 TMRM AAT Bioquest Cat# 22221 MitoTracker Red CMXRos YEASEN Cat# 40741ES50 Safranin O Sigma-Aldrich Cat#S2255 Rotenone Dalian Meilun Cat#MB7162 Digitonin Sigma-Aldrich Cat# D5628 Succinate Shanghai Maclin Cat# D822253 Pyruvate Sigma-Aldrich Cat# P2256 Glutamate Shanghai Maclin Cat#L810495 Malate Shanghai Maclin Cat#L813179 Ascorbate Sigma-Aldrich Cat#A7631 TMPD Shanghai Maclin Cat#T819055 ADP Shanghai Maclin Cat#A844435 AMP Sigma-Aldrich Cat#A2252 ATP Shanghai Maclin Cat#A800906 FCCP Dalian Meilun Cat#MB3642 (Continued on next page) e2 Cell Metabolism 31, 892–908.e1–e11, May 5, 2020 .. REAGENT or RESOURCE SOURCE IDENTIFIER Malonic acid Shanghai Maclin Cat#M813040 Antimycin A Dalian Meilun Cat# MB1384 Sodium azide Sigma-Aldrich Cat#S8032 Oligomycin Sigma-Aldrich Cat#O4876 Lactobionic acid Shanghai Maclin Cat#L812453 Taurine Sigma-Aldrich Cat#T0625 Valinomycin Shanghai Maclin Cat#V820378 Nigericin MedChemExpress Cat# HY-100381 BSA, essentially fatty acid free Equitech Bio Cat# BAH66-0100 Sodium palmitate Sigma-Aldrich Cat# P9767 Oleic acid Sigma-Aldrich Cat#O1008 DAPI Invitrogen Cat#S36939 Pazopanib Selleck Cat#S3012 ZM336372 Selleck Cat#S2720 SU1498 Selleck Cat#S6535 Tyrphostin AG 1296 Selleck Cat#S8024 Liver Perfusion Medium Thermo Fisher Scientific Cat#17701-038 Liver Digestion Medium Thermo Fisher Scientific Cat#17701-034 Pronase E Roche Cat#10165921001 Collagenase IV GIBCO Cat#17104019 DNase I Roche Cat#10104159001 Crystal violet Sinopharm Chemical Reagent Cat#71012314 Critical Commercial Assays BCA Protein assay kit Thermo Fisher Scientific Cat#23225 Transcriptor first-strand cDNA synthesis kit Roche Cat#04896866001 Triglyceride (TG) assay kit Wako Cat#290-63701 Cholesterol assay kit Wako Cat#294-65801 NEFA assay kit Wako Cat#294-63601 Triglyceride (TG) assay kit Solarbio Cat#BC0625 Mouse TNF ELISA kit Cloud-Clone Co. Cat#SEA133Mu Mouse MCP1(CCL2) ELISA kit Cloud-Clone Co. Cat#SEA087Mu Cell Counting Kit-8 assay kit Bimake Cat#B34304 Enhanced enzyme-labeled goat anti-rabbit IgG kit Beijing ZSGB-Bio Cat#PV-9001 3,30-Diaminobenzidine (DAB) substrate kit Beijing ZSGB-Bio Cat#ZLI-9018 RNA 6000 Nano kit Agilent Cat#5067-1511 MGIEasy RNA Library Prep Kit MGI Tech Co. Cat#1000006384 Deposited Data RNA-seq data of HFHC-fed mice This paper, NCBI SRA PRJNA613854 RNA-seq data of HFD-fed mice This paper, NCBI SRA PRJNA613938 RNA-seq data of HFHC-fed mice treated with CC and sorafenib This paper, NCBI SRA PRJNA613940 RNA-seq data of NASH monkeys This paper, NCBI SRA PRJNA614574 Proteomic data of NASH monkeys This paper, PRIDE PXD018256 Phospho-proteomic data of PA-treated L02 This paper, PRIDE PXD018214 Publicly available transcriptomic datasets from sorafenib treated HCC cell lines GEO database GSE43053, GSE73571, GSE96793, GSE102863 (Continued on next page) Cell Metabolism 31, 892–908.e1–e11, May 5, 2020 e3 .. REAGENT or RESOURCE SOURCE IDENTIFIER Experimental Models: Cell Lines Human: L02 (HL-7702) China Center for Type Culture Collection, Wuhan, China.

    Enzyme-linked Immunosorbent Assay:

    Article Title: Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis.
    Article Snippet: Compound Servicebio Cat#4583 Oil Red O Sigma-Aldrich Cat# 625 TMRM AAT Bioquest Cat# 22221 MitoTracker Red CMXRos YEASEN Cat# 40741ES50 Safranin O Sigma-Aldrich Cat#S2255 Rotenone Dalian Meilun Cat#MB7162 Digitonin Sigma-Aldrich Cat# D5628 Succinate Shanghai Maclin Cat# D822253 Pyruvate Sigma-Aldrich Cat# P2256 Glutamate Shanghai Maclin Cat#L810495 Malate Shanghai Maclin Cat#L813179 Ascorbate Sigma-Aldrich Cat#A7631 TMPD Shanghai Maclin Cat#T819055 ADP Shanghai Maclin Cat#A844435 AMP Sigma-Aldrich Cat#A2252 ATP Shanghai Maclin Cat#A800906 FCCP Dalian Meilun Cat#MB3642 (Continued on next page) e2 Cell Metabolism 31, 892–908.e1–e11, May 5, 2020 .. REAGENT or RESOURCE SOURCE IDENTIFIER Malonic acid Shanghai Maclin Cat#M813040 Antimycin A Dalian Meilun Cat# MB1384 Sodium azide Sigma-Aldrich Cat#S8032 Oligomycin Sigma-Aldrich Cat#O4876 Lactobionic acid Shanghai Maclin Cat#L812453 Taurine Sigma-Aldrich Cat#T0625 Valinomycin Shanghai Maclin Cat#V820378 Nigericin MedChemExpress Cat# HY-100381 BSA, essentially fatty acid free Equitech Bio Cat# BAH66-0100 Sodium palmitate Sigma-Aldrich Cat# P9767 Oleic acid Sigma-Aldrich Cat#O1008 DAPI Invitrogen Cat#S36939 Pazopanib Selleck Cat#S3012 ZM336372 Selleck Cat#S2720 SU1498 Selleck Cat#S6535 Tyrphostin AG 1296 Selleck Cat#S8024 Liver Perfusion Medium Thermo Fisher Scientific Cat#17701-038 Liver Digestion Medium Thermo Fisher Scientific Cat#17701-034 Pronase E Roche Cat#10165921001 Collagenase IV GIBCO Cat#17104019 DNase I Roche Cat#10104159001 Crystal violet Sinopharm Chemical Reagent Cat#71012314 Critical Commercial Assays BCA Protein assay kit Thermo Fisher Scientific Cat#23225 Transcriptor first-strand cDNA synthesis kit Roche Cat#04896866001 Triglyceride (TG) assay kit Wako Cat#290-63701 Cholesterol assay kit Wako Cat#294-65801 NEFA assay kit Wako Cat#294-63601 Triglyceride (TG) assay kit Solarbio Cat#BC0625 Mouse TNF ELISA kit Cloud-Clone Co. Cat#SEA133Mu Mouse MCP1(CCL2) ELISA kit Cloud-Clone Co. Cat#SEA087Mu Cell Counting Kit-8 assay kit Bimake Cat#B34304 Enhanced enzyme-labeled goat anti-rabbit IgG kit Beijing ZSGB-Bio Cat#PV-9001 3,30-Diaminobenzidine (DAB) substrate kit Beijing ZSGB-Bio Cat#ZLI-9018 RNA 6000 Nano kit Agilent Cat#5067-1511 MGIEasy RNA Library Prep Kit MGI Tech Co. Cat#1000006384 Deposited Data RNA-seq data of HFHC-fed mice This paper, NCBI SRA PRJNA613854 RNA-seq data of HFD-fed mice This paper, NCBI SRA PRJNA613938 RNA-seq data of HFHC-fed mice treated with CC and sorafenib This paper, NCBI SRA PRJNA613940 RNA-seq data of NASH monkeys This paper, NCBI SRA PRJNA614574 Proteomic data of NASH monkeys This paper, PRIDE PXD018256 Phospho-proteomic data of PA-treated L02 This paper, PRIDE PXD018214 Publicly available transcriptomic datasets from sorafenib treated HCC cell lines GEO database GSE43053, GSE73571, GSE96793, GSE102863 (Continued on next page) Cell Metabolism 31, 892–908.e1–e11, May 5, 2020 e3 .. REAGENT or RESOURCE SOURCE IDENTIFIER Experimental Models: Cell Lines Human: L02 (HL-7702) China Center for Type Culture Collection, Wuhan, China.

    CCK-8 Assay:

    Article Title: Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis.
    Article Snippet: Compound Servicebio Cat#4583 Oil Red O Sigma-Aldrich Cat# 625 TMRM AAT Bioquest Cat# 22221 MitoTracker Red CMXRos YEASEN Cat# 40741ES50 Safranin O Sigma-Aldrich Cat#S2255 Rotenone Dalian Meilun Cat#MB7162 Digitonin Sigma-Aldrich Cat# D5628 Succinate Shanghai Maclin Cat# D822253 Pyruvate Sigma-Aldrich Cat# P2256 Glutamate Shanghai Maclin Cat#L810495 Malate Shanghai Maclin Cat#L813179 Ascorbate Sigma-Aldrich Cat#A7631 TMPD Shanghai Maclin Cat#T819055 ADP Shanghai Maclin Cat#A844435 AMP Sigma-Aldrich Cat#A2252 ATP Shanghai Maclin Cat#A800906 FCCP Dalian Meilun Cat#MB3642 (Continued on next page) e2 Cell Metabolism 31, 892–908.e1–e11, May 5, 2020 .. REAGENT or RESOURCE SOURCE IDENTIFIER Malonic acid Shanghai Maclin Cat#M813040 Antimycin A Dalian Meilun Cat# MB1384 Sodium azide Sigma-Aldrich Cat#S8032 Oligomycin Sigma-Aldrich Cat#O4876 Lactobionic acid Shanghai Maclin Cat#L812453 Taurine Sigma-Aldrich Cat#T0625 Valinomycin Shanghai Maclin Cat#V820378 Nigericin MedChemExpress Cat# HY-100381 BSA, essentially fatty acid free Equitech Bio Cat# BAH66-0100 Sodium palmitate Sigma-Aldrich Cat# P9767 Oleic acid Sigma-Aldrich Cat#O1008 DAPI Invitrogen Cat#S36939 Pazopanib Selleck Cat#S3012 ZM336372 Selleck Cat#S2720 SU1498 Selleck Cat#S6535 Tyrphostin AG 1296 Selleck Cat#S8024 Liver Perfusion Medium Thermo Fisher Scientific Cat#17701-038 Liver Digestion Medium Thermo Fisher Scientific Cat#17701-034 Pronase E Roche Cat#10165921001 Collagenase IV GIBCO Cat#17104019 DNase I Roche Cat#10104159001 Crystal violet Sinopharm Chemical Reagent Cat#71012314 Critical Commercial Assays BCA Protein assay kit Thermo Fisher Scientific Cat#23225 Transcriptor first-strand cDNA synthesis kit Roche Cat#04896866001 Triglyceride (TG) assay kit Wako Cat#290-63701 Cholesterol assay kit Wako Cat#294-65801 NEFA assay kit Wako Cat#294-63601 Triglyceride (TG) assay kit Solarbio Cat#BC0625 Mouse TNF ELISA kit Cloud-Clone Co. Cat#SEA133Mu Mouse MCP1(CCL2) ELISA kit Cloud-Clone Co. Cat#SEA087Mu Cell Counting Kit-8 assay kit Bimake Cat#B34304 Enhanced enzyme-labeled goat anti-rabbit IgG kit Beijing ZSGB-Bio Cat#PV-9001 3,30-Diaminobenzidine (DAB) substrate kit Beijing ZSGB-Bio Cat#ZLI-9018 RNA 6000 Nano kit Agilent Cat#5067-1511 MGIEasy RNA Library Prep Kit MGI Tech Co. Cat#1000006384 Deposited Data RNA-seq data of HFHC-fed mice This paper, NCBI SRA PRJNA613854 RNA-seq data of HFD-fed mice This paper, NCBI SRA PRJNA613938 RNA-seq data of HFHC-fed mice treated with CC and sorafenib This paper, NCBI SRA PRJNA613940 RNA-seq data of NASH monkeys This paper, NCBI SRA PRJNA614574 Proteomic data of NASH monkeys This paper, PRIDE PXD018256 Phospho-proteomic data of PA-treated L02 This paper, PRIDE PXD018214 Publicly available transcriptomic datasets from sorafenib treated HCC cell lines GEO database GSE43053, GSE73571, GSE96793, GSE102863 (Continued on next page) Cell Metabolism 31, 892–908.e1–e11, May 5, 2020 e3 .. REAGENT or RESOURCE SOURCE IDENTIFIER Experimental Models: Cell Lines Human: L02 (HL-7702) China Center for Type Culture Collection, Wuhan, China.

    RNA Sequencing:

    Article Title: Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis.
    Article Snippet: Compound Servicebio Cat#4583 Oil Red O Sigma-Aldrich Cat# 625 TMRM AAT Bioquest Cat# 22221 MitoTracker Red CMXRos YEASEN Cat# 40741ES50 Safranin O Sigma-Aldrich Cat#S2255 Rotenone Dalian Meilun Cat#MB7162 Digitonin Sigma-Aldrich Cat# D5628 Succinate Shanghai Maclin Cat# D822253 Pyruvate Sigma-Aldrich Cat# P2256 Glutamate Shanghai Maclin Cat#L810495 Malate Shanghai Maclin Cat#L813179 Ascorbate Sigma-Aldrich Cat#A7631 TMPD Shanghai Maclin Cat#T819055 ADP Shanghai Maclin Cat#A844435 AMP Sigma-Aldrich Cat#A2252 ATP Shanghai Maclin Cat#A800906 FCCP Dalian Meilun Cat#MB3642 (Continued on next page) e2 Cell Metabolism 31, 892–908.e1–e11, May 5, 2020 .. REAGENT or RESOURCE SOURCE IDENTIFIER Malonic acid Shanghai Maclin Cat#M813040 Antimycin A Dalian Meilun Cat# MB1384 Sodium azide Sigma-Aldrich Cat#S8032 Oligomycin Sigma-Aldrich Cat#O4876 Lactobionic acid Shanghai Maclin Cat#L812453 Taurine Sigma-Aldrich Cat#T0625 Valinomycin Shanghai Maclin Cat#V820378 Nigericin MedChemExpress Cat# HY-100381 BSA, essentially fatty acid free Equitech Bio Cat# BAH66-0100 Sodium palmitate Sigma-Aldrich Cat# P9767 Oleic acid Sigma-Aldrich Cat#O1008 DAPI Invitrogen Cat#S36939 Pazopanib Selleck Cat#S3012 ZM336372 Selleck Cat#S2720 SU1498 Selleck Cat#S6535 Tyrphostin AG 1296 Selleck Cat#S8024 Liver Perfusion Medium Thermo Fisher Scientific Cat#17701-038 Liver Digestion Medium Thermo Fisher Scientific Cat#17701-034 Pronase E Roche Cat#10165921001 Collagenase IV GIBCO Cat#17104019 DNase I Roche Cat#10104159001 Crystal violet Sinopharm Chemical Reagent Cat#71012314 Critical Commercial Assays BCA Protein assay kit Thermo Fisher Scientific Cat#23225 Transcriptor first-strand cDNA synthesis kit Roche Cat#04896866001 Triglyceride (TG) assay kit Wako Cat#290-63701 Cholesterol assay kit Wako Cat#294-65801 NEFA assay kit Wako Cat#294-63601 Triglyceride (TG) assay kit Solarbio Cat#BC0625 Mouse TNF ELISA kit Cloud-Clone Co. Cat#SEA133Mu Mouse MCP1(CCL2) ELISA kit Cloud-Clone Co. Cat#SEA087Mu Cell Counting Kit-8 assay kit Bimake Cat#B34304 Enhanced enzyme-labeled goat anti-rabbit IgG kit Beijing ZSGB-Bio Cat#PV-9001 3,30-Diaminobenzidine (DAB) substrate kit Beijing ZSGB-Bio Cat#ZLI-9018 RNA 6000 Nano kit Agilent Cat#5067-1511 MGIEasy RNA Library Prep Kit MGI Tech Co. Cat#1000006384 Deposited Data RNA-seq data of HFHC-fed mice This paper, NCBI SRA PRJNA613854 RNA-seq data of HFD-fed mice This paper, NCBI SRA PRJNA613938 RNA-seq data of HFHC-fed mice treated with CC and sorafenib This paper, NCBI SRA PRJNA613940 RNA-seq data of NASH monkeys This paper, NCBI SRA PRJNA614574 Proteomic data of NASH monkeys This paper, PRIDE PXD018256 Phospho-proteomic data of PA-treated L02 This paper, PRIDE PXD018214 Publicly available transcriptomic datasets from sorafenib treated HCC cell lines GEO database GSE43053, GSE73571, GSE96793, GSE102863 (Continued on next page) Cell Metabolism 31, 892–908.e1–e11, May 5, 2020 e3 .. REAGENT or RESOURCE SOURCE IDENTIFIER Experimental Models: Cell Lines Human: L02 (HL-7702) China Center for Type Culture Collection, Wuhan, China.



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