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nme2 inhibitor stauprimide  (MedChemExpress)


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    Structured Review

    MedChemExpress nme2 inhibitor stauprimide
    Nme2 Inhibitor Stauprimide, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy-n6747/Stauprimide/pm41713665-147-19-25
    Average 94 stars, based on 2 article reviews
    nme2 inhibitor stauprimide - by Bioz Stars, 2026-10
    94/100 stars

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    other:

    Article Title: A Capsicum annuum L. seed extract exerts anti-neuroexcitotoxicity in HT22 hippocampal neurons.
    Article Snippet: The following reagents were procured from various manufacturers: 2′,7′-dichlorofluorescin diacetate (DCFH-DA), 4′,6-diamidino-2-phenylindole dihydrochloride (DAPI), capsaicin (cat no. M2028), ethyl alcohol, L-glutamic acid monosodium salt monohydrate (glutamate), N-acetyl-L-cysteine (NAC), N-(1naphthyl)-ethylenediamine dihydrochloride, phosphoric acid, sodium hydroxide, tetraethyl ethylenediamine (TEMED), Trizma base, and Tween 20 (Sigma-Aldrich, St Louis, MO, USA); antibiotic antimycotic solution, Dulbecco’s modified Eagle’s medium (DMEM), Dulbecco’s phosphate-buffered saline (DPBS), fetal bovine serum (FBS), and trypsin–ethylenediaminetetraacetic acid (EDTA) (Welgene, Daegu, Korea); capsiate (cat no. HY-N8377), luteolin (cat no. HY-N6747) and lutein (cat no. HY-N0162) (MedChemExpress, Monmouth Junction, NJ, USA); 10% ammonium persulfate solution (APS), radioimmunoprecipitation assay buffer (RIPA), and skim milk (LPS Solution, Daejeon, Korea); bovine serum albumin (BSA) (GenDEPOT, Barker, TX, USA); 4% paraformaldehyde (PFA), 10× Tris glycine buffer, and 10× Tris glycine-SDS buffer (XOGENE, Daejeon, Korea); lactate dehydrogenase (LDH) cytotoxicity assay kit and water-soluble tetrazolium salt (WST)-8 based cell viability assay kit (DoGen, Seoul, Korea); Ca2+ assay kit (BioVision, CA, USA); PRO-PREPTM protein extraction solution (iNtRON Biotechnology, Seongnam, Korea); sodium chloride and hydrochloric acid (Samchun, Seoul, Korea); methylene alcohol (Daejung Chemicals & Metals Co., Siheung, Korea); n-butanol (J. T. Baker, Mexico City, Mexico); and polyvinylidene fluoride (PVDF) membranes (Pall Co., Port Washington, NY, USA).

    Injection:

    Article Title: NME2-driven epigenetic control of inflammasome-activated microglial lineage dynamics promotes sepsis-associated encephalopathy.
    Article Snippet: Microglia are critical in the neuroinflammatory cascade of sepsis-associated encephalopathy (SAE), yet their functional heterogeneity and transcriptional regulators remain poorly characterized.. Here, through single-cell RNA sequencing (scRNA-seq) of murine brains post-cecal ligation and puncture (CLP)-induced sepsis, we resolved six microglial clusters.. Notably, a subset of inflammasome-activated microglia emerged as a driver for neuroinflammation and cognitive impairment, with marked upregulation of Nlrp3, Il1b, Tnf and enriched pathways for interleukin-1β (IL-1β) production and neuron death.



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