aristolactam i (MedChemExpress)
92
Structured Review
MedChemExpress
aristolactam i
Aristolactam I, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hy-n2013/Aristolactam+I/pm38428544-40-4-21
Average 92 stars, based on 2 article reviews
Aristolactam I, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hy-n2013/Aristolactam+I/pm38428544-40-4-21
Average 92 stars, based on 2 article reviews
aristolactam i - by Bioz Stars,
2026-10
92/100 stars
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other:Article Title: Mitochondrial uptake of aristolactam I plays a critical role in its toxicity. Article Snippet: Aristolochic acid I (AAI), a component of aristolochic acids, can be converted to the toxic metabolite Aristolactam I (ALI) in vivo which forms aristolactam-nitrenium with delocalized positive charges.. It is widely accepted that delocalized lipophilic cations can accumulate in mitochondria due to the highly negatively charged microenvironment of the mitochondrial matrix, but the uptake of ALI by mitochondria is not known.. In this study, the cell uptake and mitochondrial localization of ALI, and its subsequent impact on mitochondrial function were investigated. |