hy n1497 (MedChemExpress)
94
Structured Review
MedChemExpress
hy n1497
Hy N1497, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hy-n1497/Plumbagin/pmc11035880-46-1-7
Average 94 stars, based on 8 article reviews
Hy N1497, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hy-n1497/Plumbagin/pmc11035880-46-1-7
Average 94 stars, based on 8 article reviews
hy n1497 - by Bioz Stars,
2026-10
94/100 stars
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Injection:Article Title: Plumbagin improves myocardial fibrosis after myocardial infarction by inhibiting the AKT/mTOR pathway to upregulate autophagy levels. Article Snippet: Cardiac fibrosis is a chronic inflammatory response that considerably impacts cardiac function following myocardial infarction (MI).. Although Plumbagin, a natural compound, has been shown to have anti-fibrotic effects by suppresses the ROS and NF-κB pathways in liver fibrosis, its role in regulating cardiac function and cardiac fibrosis post-MI remains unknown.. In this study, we demonstrate that Plumbagin effectively inhibits TGFβ1-induced myocardial fibroblast fibrosis and promotes autophagy activation by suppressing the AKT/mTOR pathway. Virus:Article Title: Inhibition of mPTP and GSDME-mediated pyroptosis alleviates lung injury in septic mice. Article Snippet: Objective: To explore the role of mitochondrial permeability transition pore (mPTP) and gasdermin E (GSDME) mediated pyroptosis in septic lung injury in mice model. Methods: Adult male c57BL/6J mice were randomly assigned with 10 mice in each group.. Sepsis model was established by cecal ligation and puncture (CLP) operation.. Alisporivir (AL) was used to inhibit the opening of mPTP, plumbagin (PL) was used to open mPTP. Bioprocessing:Article Title: Inhibition of mPTP and GSDME-mediated pyroptosis alleviates lung injury in septic mice. Article Snippet: Objective: To explore the role of mitochondrial permeability transition pore (mPTP) and gasdermin E (GSDME) mediated pyroptosis in septic lung injury in mice model. Methods: Adult male c57BL/6J mice were randomly assigned with 10 mice in each group.. Sepsis model was established by cecal ligation and puncture (CLP) operation.. Alisporivir (AL) was used to inhibit the opening of mPTP, plumbagin (PL) was used to open mPTP. Synthesized:Article Title: Inhibition of mPTP and GSDME-mediated pyroptosis alleviates lung injury in septic mice. Article Snippet: Objective: To explore the role of mitochondrial permeability transition pore (mPTP) and gasdermin E (GSDME) mediated pyroptosis in septic lung injury in mice model. Methods: Adult male c57BL/6J mice were randomly assigned with 10 mice in each group.. Sepsis model was established by cecal ligation and puncture (CLP) operation.. Alisporivir (AL) was used to inhibit the opening of mPTP, plumbagin (PL) was used to open mPTP. Multiple Displacement Amplification:Article Title: Inhibition of mPTP and GSDME-mediated pyroptosis alleviates lung injury in septic mice. Article Snippet: Objective: To explore the role of mitochondrial permeability transition pore (mPTP) and gasdermin E (GSDME) mediated pyroptosis in septic lung injury in mice model. Methods: Adult male c57BL/6J mice were randomly assigned with 10 mice in each group.. Sepsis model was established by cecal ligation and puncture (CLP) operation.. Alisporivir (AL) was used to inhibit the opening of mPTP, plumbagin (PL) was used to open mPTP. Membrane:Article Title: Inhibition of mPTP and GSDME-mediated pyroptosis alleviates lung injury in septic mice. Article Snippet: Objective: To explore the role of mitochondrial permeability transition pore (mPTP) and gasdermin E (GSDME) mediated pyroptosis in septic lung injury in mice model. Methods: Adult male c57BL/6J mice were randomly assigned with 10 mice in each group.. Sepsis model was established by cecal ligation and puncture (CLP) operation.. Alisporivir (AL) was used to inhibit the opening of mPTP, plumbagin (PL) was used to open mPTP. ATP Assay:Article Title: Inhibition of mPTP and GSDME-mediated pyroptosis alleviates lung injury in septic mice. Article Snippet: Objective: To explore the role of mitochondrial permeability transition pore (mPTP) and gasdermin E (GSDME) mediated pyroptosis in septic lung injury in mice model. Methods: Adult male c57BL/6J mice were randomly assigned with 10 mice in each group.. Sepsis model was established by cecal ligation and puncture (CLP) operation.. Alisporivir (AL) was used to inhibit the opening of mPTP, plumbagin (PL) was used to open mPTP. Enzyme-linked Immunosorbent Assay:Article Title: Inhibition of mPTP and GSDME-mediated pyroptosis alleviates lung injury in septic mice. Article Snippet: Objective: To explore the role of mitochondrial permeability transition pore (mPTP) and gasdermin E (GSDME) mediated pyroptosis in septic lung injury in mice model. Methods: Adult male c57BL/6J mice were randomly assigned with 10 mice in each group.. Sepsis model was established by cecal ligation and puncture (CLP) operation.. Alisporivir (AL) was used to inhibit the opening of mPTP, plumbagin (PL) was used to open mPTP. Marker:Article Title: Inhibition of mPTP and GSDME-mediated pyroptosis alleviates lung injury in septic mice. Article Snippet: Objective: To explore the role of mitochondrial permeability transition pore (mPTP) and gasdermin E (GSDME) mediated pyroptosis in septic lung injury in mice model. Methods: Adult male c57BL/6J mice were randomly assigned with 10 mice in each group.. Sepsis model was established by cecal ligation and puncture (CLP) operation.. Alisporivir (AL) was used to inhibit the opening of mPTP, plumbagin (PL) was used to open mPTP. |