Review



silibinin  (MedChemExpress)


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    Structured Review

    MedChemExpress silibinin
    Silibinin, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy-n0779a/Silybin/pm34883284-38-0-2
    Average 94 stars, based on 6 article reviews
    silibinin - by Bioz Stars, 2026-10
    94/100 stars

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    Related Articles

    Microscopy:

    Article Title: Silybin Improves Acute Kidney Injury by Regulating HDAC6/NF-κB/NLRP3 Signaling to Reduce Inflammation and Ferroptosis.
    Article Snippet: Inflammation and ferroptosis play a crucial role in cisplatin (CP)-induced acute kidney injury (AKI).. Silybin (SYB), a polyphenolic flavonoid, has shown renal protective effects, but its underlying mechanisms remain unclear.. CP-induced HK-2 cell and mouse AKI models were used to explore the role of SYB.

    Concentration Assay:

    Article Title: BNIP3 contributes to silibinin-induced DNA double strand breaks in glioma cells via inhibition of mTOR.
    Article Snippet: BNIP3 is found to eliminate cancer cells via causing mitochondrial damage and endoplasmic reticulum stress, but it remains elusive of its role in regulating DNA double strand breaks (DSBs).. In this study, we find that silibinin triggers DNA DSBs, ROS accumulation and expressional upregulation of BNIP3 in glioma cells.. Mitigation of ROS with antioxidant GSH significantly inhibits silibinin-induced DNA DSBs and glioma cell death.



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