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isobavachin  (MedChemExpress)


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    Structured Review

    MedChemExpress isobavachin
    Isobavachin, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy-n0762/Isobavachin/pm35973629-76-18-46
    Average 93 stars, based on 5 article reviews
    isobavachin - by Bioz Stars, 2026-10
    93/100 stars

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    other:

    Article Title: Bavachinin, a main compound of Psoraleae Fructus, facilitates GSDMD-mediated pyroptosis and causes hepatotoxicity in mice.
    Article Snippet: Psoraleae Fructus (PF, Psoralea corylifolia L.), a traditional medicine with a long history of application, is widely used clinically for the treatment of various diseases.. However, the reports of PF-related adverse reactions, such as hepatotoxicity, phototoxic dermatitis, and allergy, are increasing year by year, with liver injury being the mostly common.. Our previous studies have demonstrated that PF and its preparations can cause liver injury in lipopolysaccharide (LPS)-mediated susceptibility mouse model, but the mechanism of PF-related liver injury is unclear.

    Article Title: Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity.
    Article Snippet: Psoraleae Fructus (PF) is a well-known traditional herbal medicine in China, and it is widely used for osteoporosis, vitiligo, and other diseases in clinical settings.. However, liver injury caused by PF and its preparations has been frequently reported in recent years.. Our previous studies have demonstrated that PF could cause idiosyncratic drug-induced liver injury (IDILI), but the mechanism underlying its hepatotoxicity remains unclear.

    Article Title: Discovery of Bakuchiol as Aim2 Inflammasome Activator and Cause Hepatotoxicity
    Article Snippet: 2.3 Drug, reagents, and antibodies Bakuchiol (HY-N0235), angelicin (HY-N0763), bavachin (HY-N0233), bavachinin (HY-N0234), corylin (HY-N0236), daidzin (HY-N0018), isobavachin (HY-N0762), isobavachalcone (HY-13065), neobavaisoflavone (HY-N0720), psoralidin (HYN0232),psoralen (HY-N0053), 5-methoxypsoralen (HY-N0370), 8-methoxypsoralen (HY-30151) were brought from MedChemExpress (NJ, USA).

    Article Title: Discovery of bakuchiol as an AIM2 inflammasome activator and cause of hepatotoxicity.
    Article Snippet: Ethnopharmacological relevance: Psoralea corylifolia (P. corylifolia Linn.) is a traditional Chinese medicinal plant that exhibits significant aphrodisiac, diuretic, and anti-rheumatic effects.. However, it has been reported to cause hepatic injury, but the precise mechanisms remain unclear.. Aim of the study: To evaluate the safety and risk of P. corylifolia and to elucidate the underlying mechanisms of drug-induced liver injury.

    Colony Assay:

    Article Title: Exploring the mechanisms of Hu-gu-xiao-ji formula and its components for treatment on non-small cell lung cancer using UPLC-QTOF-MS/MS, network pharmacology, and experiments.
    Article Snippet: Please cite this article as: Wang, J., Wang, X., Li, Y., Huang, Q., Li, Z., Zhao, Y., Zhang, C., Ding, L., Zhou, R., Xiao, Z., Yu, Y., Zhu, Y., Zhang, H., Exploring the mechanisms of Hu-gu-xiao-ji formula and its components for treatment on non-small cell lung cancer using UPLC-QTOF-MS/MS, network pharmacology, and experiments, Journal of Ethnopharmacology, https://doi.org/10.1016/ j.jep.2025.120637.



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    93
    MedChemExpress isobavachin
    Isobavachin, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy-n0762/Isobavachin/pm35973629-76-18-46
    Average 93 stars, based on 1 article reviews
    isobavachin - by Bioz Stars, 2026-10
    93/100 stars
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