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Siemens AG diffracplus 5000
Diffracplus 5000, supplied by Siemens AG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/diffracplus/diffracplus+5000/pm20840162-2567-5-5
Average 90 stars, based on 1 article reviews
diffracplus 5000 - by Bioz Stars, 2026-10
90/100 stars

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Article Title: UK-PharmSci 2010 - The Science of Medicines. Abstracts from the UK-PharmSci Conference, 1-3 September 2010.
Article Snippet: PXRD studies were conducted on Siemens DIFFRACplus 5000.

Article Title: Effects of Polymer and Surfactant on the Dissolution and Transformation Profiles of Cocrystals in Aqueous Media
Article Snippet: Capturing solubility advantages of cocrystals is of great interest, and thus to understand the mechanism by which different excipients could maintain the supersaturation generated by cocrystals at the course of absorption in aqueous media is essential.. To achieve this aim, the impact of different excipients on dissolution behavior of indomethacin−saccharin (IND−SAC) were monitored by measuring the concentrations of cocrystal components in the absence and presence of various concentration of excipients by HPLC, and solid phases were analyzed by differential scanning calorimetry after each experiment and the potential of Raman spectroscopy for monitoring phase transformations in situ was tested.. No dissolution advantage was offered by cocrystals in the absence of any solution additive.

X-ray Diffraction:

Article Title: Solid-state vibrational spectroscopic investigation of cocrystals and salt of indomethacin
Article Snippet: Knowledge and control of the solid forms of active pharmaceutical ingredients are important aspects of drug development in the pharmaceutical industry.. In this paper, the process of the molecular selfassembly of saccharin cocrystals and the 2-amino-5-methylpyridine salt of indomethacin, in terms of the hydrogen bonding patterns, has been studied in the solid-state using vibrational spectroscopy (Raman and infrared).. Interaction patterns in the respective crystalline states were obtained from the single crystal data.



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