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aptt-based algorithm  (Johns Hopkins HealthCare)

 
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    Johns Hopkins HealthCare aptt-based algorithm
    Aptt Based Algorithm, supplied by Johns Hopkins HealthCare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aptt/aptt+based+algorithm/pm25740425-34-38-2
    Average 90 stars, based on 1 article reviews
    aptt-based algorithm - by Bioz Stars, 2026-09
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    Related Articles

    other:

    Article Title: Retrospective cohort study comparing activated partial thromboplastin time versus anti-factor Xa activity nomograms for therapeutic unfractionated heparin monitoring in pediatrics.
    Article Snippet: In May 2010, the hospital policy for monitoring UFH at the Johns Hopkins Hospital, including the Children’s Center, changed from using the aPTT-based algorithm to using the anti-Xabased algorithm .

    Article Title: Retrospective cohort study comparing activated partial thromboplastin time versus anti-factor Xa activity nomograms for therapeutic unfractionated heparin monitoring in pediatrics.
    Article Snippet: At the Johns Hopkins Hospital over a 28- month period from 2010 to 2011, a cohort of pediatric patients on UFH was managed using an anti-Xa algorithm; prior to that, patients on UFH had been managed with an aPTT-based algorithm.



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    Image Search Results


    (A) NO release rates from bare TPU and hydrogel-coated surfaces measured by a Griess-based assay (n = 6). (B) Fluorescence images of platelet adhesion on bare TPU, PDM, PD@Cu, and PDM@Cu surfaces with and without NO donors. (C) Quantification of platelet adhesion by LDH assay (n = 6). (D) SEM images of platelet morphology on bare TPU and hydrogel-coated surfaces. (E) APTT and (F) TT of bare TPU and hydrogel-coated surfaces (n = 3). (G) Digital photographs of thrombus formation on bare TPU and hydrogel-coated surfaces after 5, 10, and 15 min during recalcification assays.

    Journal: Bioactive Materials

    Article Title: Robust and durable zwitterionic hydrogel coating with catechol-Cu 2+ coordination for antithrombotic and antibacterial blood-contacting devices

    doi: 10.1016/j.bioactmat.2026.02.036

    Figure Lengend Snippet: (A) NO release rates from bare TPU and hydrogel-coated surfaces measured by a Griess-based assay (n = 6). (B) Fluorescence images of platelet adhesion on bare TPU, PDM, PD@Cu, and PDM@Cu surfaces with and without NO donors. (C) Quantification of platelet adhesion by LDH assay (n = 6). (D) SEM images of platelet morphology on bare TPU and hydrogel-coated surfaces. (E) APTT and (F) TT of bare TPU and hydrogel-coated surfaces (n = 3). (G) Digital photographs of thrombus formation on bare TPU and hydrogel-coated surfaces after 5, 10, and 15 min during recalcification assays.

    Article Snippet: Cell counting kit-8 (CCK-8), activated partial thromboplastin time (APTT) kit, thrombin time (TT) test kit, and enhanced BCA protein assay kit were obtained from Beyotime Biotechnology Inc., Shanghai, China.

    Techniques: Griess Assay, Fluorescence, Lactate Dehydrogenase Assay

    Anticoagulant performance of surface coatings. (A) Protein adsorption on the surfaces. (B) Platelet adhesion density quantified from (C) fluorescence images of DiOC6-stained platelets. Clotting times determined using (D) APTT and (E) TT assays. Statistical comparisons of samples with PET were performed using a one-way ANOVA test.

    Journal: Materials Today Bio

    Article Title: Antithrombotic and antibacterial surface coating based on spiky silver nanoparticles: A counterattack against clotting and biofilm

    doi: 10.1016/j.mtbio.2026.102762

    Figure Lengend Snippet: Anticoagulant performance of surface coatings. (A) Protein adsorption on the surfaces. (B) Platelet adhesion density quantified from (C) fluorescence images of DiOC6-stained platelets. Clotting times determined using (D) APTT and (E) TT assays. Statistical comparisons of samples with PET were performed using a one-way ANOVA test.

    Article Snippet: For the APTT assay, 50 μL of PPP was combined with 50 μL of APTT reagent (Dade® Actin FSL, Siemens Healthineers, Erlangen, Germany) and incubated at 37 °C for 30 min.

    Techniques: Adsorption, Fluorescence, Staining, Coagulation