polyclonal anti endothelin receptor a (Alomone Labs)

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Alomone Labs polyclonal anti endothelin receptor a
ET-1 concentrations are not significantly different in BALB-STD or IFN-γ-STD mice compared with controls. Samples are peptide extracts from total lung homogenates. Data are expressed as means ± SEM. n = 5 mice in two independent experiments. CON, control; ET-1, <t>endothelin-1;</t> IFN, interferon; STD, short-term depletion.

ET-1 concentrations are not significantly different in BALB-STD or IFN-γ-STD mice compared with controls. Samples are peptide extracts from total lung homogenates. Data are expressed as means ± SEM. n = 5 mice in two independent experiments. CON, control; ET-1, <t>endothelin-1;</t> IFN, interferon; STD, short-term depletion.

Polyclonal Anti Endothelin Receptor A, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 28 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/aer-004/Anti-Endothelin+Receptor+A+Antibody/pmc04729275-85-0-16
Average 91 stars, based on 28 article reviews

polyclonal anti endothelin receptor a - by Bioz Stars, 2026-09

91/100 stars

Images

1) Product Images from "Vascular Dysfunction in Pneumocystis -Associated Pulmonary Hypertension Is Related to Endothelin Response and Adrenomedullin Concentration"

Article Title: Vascular Dysfunction in Pneumocystis -Associated Pulmonary Hypertension Is Related to Endothelin Response and Adrenomedullin Concentration

Journal: The American Journal of Pathology

doi: 10.1016/j.ajpath.2015.10.008

Figure Legend Snippet: ET-1 concentrations are not significantly different in BALB-STD or IFN-γ-STD mice compared with controls. Samples are peptide extracts from total lung homogenates. Data are expressed as means ± SEM. n = 5 mice in two independent experiments. CON, control; ET-1, endothelin-1; IFN, interferon; STD, short-term depletion.

Techniques Used:

Figure Legend Snippet: Small pulmonary artery profiles show increasing vasoconstriction when treated with a cumulative dose response of ET-1. Shown is a representative profile from a BALB-STD mouse precision cut lung slices sample. ET-1, endothelin-1; STD, short-term depletion.

Techniques Used:

The response to ET-1 is enhanced in BALB-STD mice. A: Vasoconstriction in small pulmonary artery profiles in BALB-STD mice is significantly greater over the range of 10−10 to 10−9 ET-1. B: This coincides with a significant increase in the ETAR in BALB-STD mice total lung tissue as indicated by quantification of Western blot analysis. Data are expressed as means ± SEM. n = 4 to 5 (B) or n = 16 to 35 profiles per group across 4 to 5 mice (A) in two independent experiments. ∗P ≤ 0.05 versus IFN-γ-STD and controls. CON, control; ETAR, endothelin receptor A; ET-1, endothelin-1; IFN, interferon; STD, short-term depletion.

Figure Legend Snippet: The response to ET-1 is enhanced in BALB-STD mice. A: Vasoconstriction in small pulmonary artery profiles in BALB-STD mice is significantly greater over the range of 10−10 to 10−9 ET-1. B: This coincides with a significant increase in the ETAR in BALB-STD mice total lung tissue as indicated by quantification of Western blot analysis. Data are expressed as means ± SEM. n = 4 to 5 (B) or n = 16 to 35 profiles per group across 4 to 5 mice (A) in two independent experiments. ∗P ≤ 0.05 versus IFN-γ-STD and controls. CON, control; ETAR, endothelin receptor A; ET-1, endothelin-1; IFN, interferon; STD, short-term depletion.

Techniques Used: Western Blot

Western Blot:

Article Title: Endothelin-axis antagonism enhances tumor perfusion in pancreatic cancer.
Article Snippet: 42 Delivery of therapeutic agents in pancreatic cancer (PC) is impaired due to its hypovascular and 43 desmoplastic tumor microenvironment.. The Endothelin (ET)-axis is the major regulator of 44 vasomotor tone under physiological conditions and is highly upregulated in multiple cancers.. We 45 investigated the effect of dual endothelin receptor antagonist bosentan on perfusion and 46 macromolecular transport in a PC cell-fibroblast co-implantation tumor model using Dynamic 47 Contrast Enhancement Magnetic Resonance Imaging (DCE-MRI).

Immunofluorescence:

Saline:

Article Title: Effects of age and caloric restriction in the vascular response of renal arteries to endothelin-1 in rats.
Article Snippet: Cardiovascular alterations are the most prevalent cause of impaired physiological function in aged individuals with kidney being one the most affected organs.. Aging induced alterations in renal circulation are associated with a decrease in endothelium derived relaxing factors such as nitric oxide (NO) and with an increase in contracting factors such as endothelin-1(ET-1).. As caloric restriction (CR) exerts beneficial effects preventing some of the aging induced alterations in cardiovascular system, the aim of this study was to analyze the effects of age and caloric restriction in the vascular response of renal arteries to ET-1 in aged rats.

Incubation:

Article Title: Chronic exposure to low doses of estradiol-17ß increases blood pressure in young female rats: A possible role for central Endothelin-1
Article Snippet: .. Blots were probed overnight at 4 °C with polyclonal rabbit anti ET A antibody (1:200 dilution; Alomone Labs, Israel) and monoclonal mouse β-tubulin antibody (1:1,000 dilution; Millipore; Temecula, CA), washed and incubated with the appropriate secondary antibodies for 1 h at 4 °C. ..

Article Title: Irreversible and sustained upregulation of endothelin axis during oncogene-associated pancreatic inflammation and cancer
Article Snippet: .. The tissues were blocked with 2.5% horse serum and incubated with primary antibodies overnight diluted in PBS: anti-ET A R, 1:300, Alomone Labs, AER-001; anti-ET A R, 1:300, Santacruz, sc-135902; anti-ET B R, 1:300, Alomone labs, AER-002; anti-ET B R, 1:300, Santacruz, sc-21196; anti-CK19, 1:200, TROMA III, anti-F4/80, 1:80, e-Biosciences, 14-4801-82; anti-α-SMA, 1:200, Abcam, ab7817; anti-amylase 1:300, Sigma. ..

other:

Article Title: Role of endothelin receptor type A on catecholamine regulation in the olfactory bulb of DOCA-Salt hypertensive rats: Hemodynamic implications
Article Snippet: Anti-ET A , Alomone, Jerusalem, ISR , 1:500 , 18-20 h in rocking agitation.

Recombinant:

Article Title: Impaired migration and lung invasion of human melanoma by a novel small molecule targeting the transmembrane domain of death receptor p75 NTR .
Article Snippet: Reagents and tools table Reagent/resource Reference or source Identifier or catalog number Experimental models AS19 bacteria cells (E. coli) Good et al, 2000 n/a COS-7 cells (green monkey) ATCC CRL-1651 A875 sh-p75NTR cells (H. sapiens) Goh et al, 2018 n/a A875-NT cells (H. sapiens) Goh et al, 2018 n/a WM115 cells (H. sapiens) ATCC CRL-1675 © The Author(s) EMBO Molecular Medicine 13 D ow nloaded from https://w w w .em bopress.org on Septem ber 29, 2025 from IP 182.93.78.163. .. Reagent/resource Reference or source Identifier or catalog number SCID mice (M. musculus) Charles River Strain Code 394 Recombinant DNA p75NTR TMD Goh et al, 2018 n/a Ara-GFP Goh et al, 2018 n/a p75NTR-EGFP* Goh et al, 2018 n/a pMM-LR6 Fu et al, 2019 n/a Antibodies P75ntr ECD Alomone Labs ANT-007 P75ntr ECD Promega G323A H nucleolin Abcam ab136649 GAPDH Cell Signalling Technologies 2118 Actin Cell Signalling Technologies 4967 PARP Cell Signalling Technologies 9542 Fascin Invitrogen MA5-11483 Alexa FluorTM 488 Goat anti-Mouse IgG ThermoFisher A-11029 Alexa FluorTM 568 Goat anti-Rabbit ThermoFisher A-11011 Chemicals, enzymes and other reagents Chemical library Chemical Biology Consortium Sweden www.cbcs.se Div17E5 Glixx Custom synthesis Np75-4A22 SAI Life India Custom synthesis Q-vd-Oph Sigma-Aldrich 1135695-98-5 Software nmrPipe Delaglio et al, 1995 n/a Ccpnmr Vranken, 2005 n/a Statistical Analysis Software SAS Institute n/a GraphPad Prism GraphPad Software Inc n/a ..

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