fcγ chain adcc jurkat (BPS Bioscience)
93
Structured Review
BPS Bioscience
fcγ chain adcc jurkat
Fcγ Chain Adcc Jurkat, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 93/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/60541/ADCC+Bioassay+Effector+Cell+V+variant+(High+Affinity)+-+Jurkat+Recombinant+Cell+Line/pm38968862-58-26-30
Average 93 stars, based on 10 article reviews
Fcγ Chain Adcc Jurkat, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 93/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/60541/ADCC+Bioassay+Effector+Cell+V+variant+(High+Affinity)+-+Jurkat+Recombinant+Cell+Line/pm38968862-58-26-30
Average 93 stars, based on 10 article reviews
fcγ chain adcc jurkat - by Bioz Stars,
2026-09
93/100 stars
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Bioassay:Article Title: Optimization of a U937 cell-based reporter system to assess ADCC activity of ustekinumab versus trastuzumab. Article Snippet: In the present study, the human monocytic U937 cell line, which intrinsically expresses low levels of membranebound IL-12, was systematically optimized to establish a robust target cell system for a surrogate ADCC reporter assay aimed at evaluating the effector function of ustekinumab.. ADCC activity was assessed in parallel with trastuzumab, employed as a well-characterized positive control, using a bioluminescent reporter-based platform.. To induce surface IL-12 overexpression, U937 cells were stimulated with varying concentrations of IFN-γ and lipopolysaccharide (LPS), and expression levels were quantitatively assessed by flow cytometry using FITClabelled antibody staining, alongside cell viability evaluation via trypan blue exclusion. Article Title: Antibodies and methods for making and using the same Article Snippet: .. Variant Assay:Article Title: Optimization of a U937 cell-based reporter system to assess ADCC activity of ustekinumab versus trastuzumab. Article Snippet: In the present study, the human monocytic U937 cell line, which intrinsically expresses low levels of membranebound IL-12, was systematically optimized to establish a robust target cell system for a surrogate ADCC reporter assay aimed at evaluating the effector function of ustekinumab.. ADCC activity was assessed in parallel with trastuzumab, employed as a well-characterized positive control, using a bioluminescent reporter-based platform.. To induce surface IL-12 overexpression, U937 cells were stimulated with varying concentrations of IFN-γ and lipopolysaccharide (LPS), and expression levels were quantitatively assessed by flow cytometry using FITClabelled antibody staining, alongside cell viability evaluation via trypan blue exclusion. Article Title: Antibodies and methods for making and using the same Article Snippet: .. Article Title: Efficacy and mechanism of the anti-CD38 monoclonal antibody Daratumumab against primary effusion lymphoma Article Snippet: .. Recombinant Jurkat T cells expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIIa, high affinity (V158) variant and Article Title: Elotuzumab, a potential therapeutic humanized anti-SLAMF7 monoclonal antibody, enhances natural killer cell-mediated killing of primary effusion lymphoma cells Article Snippet: All PEL/MM/mantle cell lymphoma cell lines were grown in RPMI1640 (Fujifilm Wako, Osaka, Japan) supplemented with 10% FBS (Nichirei Bioscience, Tokyo, Japan), 100 IU/ml penicillin and 100 U/ml streptomycin at 37 °C, 5% CO 2 in a humidified atmosphere [ 24 ]. .. Jurkat T cells expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIIa, high affinity (V158) variant and Article Title: Trastuzumab, a monoclonal anti-HER2 antibody modulates cytotoxicity against cholangiocarcinoma via multiple mechanisms. Article Snippet: Cholangiocarcinoma (CCA) is an aggressive and fatal cancer.. The prognosis is very poor and no optimal chemotherapy has been established.. Human epidermal growth factor receptor 2 (HER2, neu, and erbB2) is highly-expressed in breast cancer and is expressed in many other tumors but poorly expressed in CCA. Article Title: Elotuzumab, a potential therapeutic humanized anti-SLAMF7 monoclonal antibody, enhances natural killer cell-mediated killing of primary effusion lymphoma cells. Article Snippet: Primary effusion lymphoma (PEL) is a rare aggressive B-cell non-Hodgkin’s lymphoma with no optimal treatment.. Signaling lymphocytic activation molecule-F7 (SLAMF7, CD319), a type I transmembrane glycoprotein highly expressed in multiple myeloma (MM), represents a promising target for mAb-based immunotherapy.. SLAMF7 also expresses on several hematopoietic lineages including NK cells. Recombinant:Article Title: Optimization of a U937 cell-based reporter system to assess ADCC activity of ustekinumab versus trastuzumab. Article Snippet: In the present study, the human monocytic U937 cell line, which intrinsically expresses low levels of membranebound IL-12, was systematically optimized to establish a robust target cell system for a surrogate ADCC reporter assay aimed at evaluating the effector function of ustekinumab.. ADCC activity was assessed in parallel with trastuzumab, employed as a well-characterized positive control, using a bioluminescent reporter-based platform.. To induce surface IL-12 overexpression, U937 cells were stimulated with varying concentrations of IFN-γ and lipopolysaccharide (LPS), and expression levels were quantitatively assessed by flow cytometry using FITClabelled antibody staining, alongside cell viability evaluation via trypan blue exclusion. Article Title: Efficacy and mechanism of the anti-CD38 monoclonal antibody Daratumumab against primary effusion lymphoma Article Snippet: .. Recombinant Jurkat T cells expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIIa, high affinity (V158) variant and Article Title: Trastuzumab, a monoclonal anti-HER2 antibody modulates cytotoxicity against cholangiocarcinoma via multiple mechanisms. Article Snippet: Cholangiocarcinoma (CCA) is an aggressive and fatal cancer.. The prognosis is very poor and no optimal chemotherapy has been established.. Human epidermal growth factor receptor 2 (HER2, neu, and erbB2) is highly-expressed in breast cancer and is expressed in many other tumors but poorly expressed in CCA. Article Title: Efficacy and mechanism of the anti-CD38 monoclonal antibody Daratumumab against primary effusion lymphoma. Article Snippet: Primary effusion lymphoma (PEL) is a rare, aggressive B cell non-Hodgkin’s lymphoma of the body cavities with malignant effusions.. The prognosis is poor, and no optimal treatment has been established.. CD38 is a type II transmembrane glycoprotein known to overexpress in multiple myeloma (MM). Expressing:Article Title: Efficacy and mechanism of the anti-CD38 monoclonal antibody Daratumumab against primary effusion lymphoma Article Snippet: .. Recombinant Jurkat T cells expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIIa, high affinity (V158) variant and Article Title: Elotuzumab, a potential therapeutic humanized anti-SLAMF7 monoclonal antibody, enhances natural killer cell-mediated killing of primary effusion lymphoma cells Article Snippet: All PEL/MM/mantle cell lymphoma cell lines were grown in RPMI1640 (Fujifilm Wako, Osaka, Japan) supplemented with 10% FBS (Nichirei Bioscience, Tokyo, Japan), 100 IU/ml penicillin and 100 U/ml streptomycin at 37 °C, 5% CO 2 in a humidified atmosphere [ 24 ]. .. Jurkat T cells expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIIa, high affinity (V158) variant and Article Title: Trastuzumab, a monoclonal anti-HER2 antibody modulates cytotoxicity against cholangiocarcinoma via multiple mechanisms. Article Snippet: Cholangiocarcinoma (CCA) is an aggressive and fatal cancer.. The prognosis is very poor and no optimal chemotherapy has been established.. Human epidermal growth factor receptor 2 (HER2, neu, and erbB2) is highly-expressed in breast cancer and is expressed in many other tumors but poorly expressed in CCA. Article Title: Elotuzumab, a potential therapeutic humanized anti-SLAMF7 monoclonal antibody, enhances natural killer cell-mediated killing of primary effusion lymphoma cells. Article Snippet: Primary effusion lymphoma (PEL) is a rare aggressive B-cell non-Hodgkin’s lymphoma with no optimal treatment.. Signaling lymphocytic activation molecule-F7 (SLAMF7, CD319), a type I transmembrane glycoprotein highly expressed in multiple myeloma (MM), represents a promising target for mAb-based immunotherapy.. SLAMF7 also expresses on several hematopoietic lineages including NK cells. Luciferase:Article Title: Efficacy and mechanism of the anti-CD38 monoclonal antibody Daratumumab against primary effusion lymphoma Article Snippet: .. Recombinant Jurkat T cells expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIIa, high affinity (V158) variant and Article Title: Elotuzumab, a potential therapeutic humanized anti-SLAMF7 monoclonal antibody, enhances natural killer cell-mediated killing of primary effusion lymphoma cells Article Snippet: All PEL/MM/mantle cell lymphoma cell lines were grown in RPMI1640 (Fujifilm Wako, Osaka, Japan) supplemented with 10% FBS (Nichirei Bioscience, Tokyo, Japan), 100 IU/ml penicillin and 100 U/ml streptomycin at 37 °C, 5% CO 2 in a humidified atmosphere [ 24 ]. .. Jurkat T cells expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIIa, high affinity (V158) variant and Article Title: Trastuzumab, a monoclonal anti-HER2 antibody modulates cytotoxicity against cholangiocarcinoma via multiple mechanisms. Article Snippet: Cholangiocarcinoma (CCA) is an aggressive and fatal cancer.. The prognosis is very poor and no optimal chemotherapy has been established.. Human epidermal growth factor receptor 2 (HER2, neu, and erbB2) is highly-expressed in breast cancer and is expressed in many other tumors but poorly expressed in CCA. Article Title: Elotuzumab, a potential therapeutic humanized anti-SLAMF7 monoclonal antibody, enhances natural killer cell-mediated killing of primary effusion lymphoma cells. Article Snippet: Primary effusion lymphoma (PEL) is a rare aggressive B-cell non-Hodgkin’s lymphoma with no optimal treatment.. Signaling lymphocytic activation molecule-F7 (SLAMF7, CD319), a type I transmembrane glycoprotein highly expressed in multiple myeloma (MM), represents a promising target for mAb-based immunotherapy.. SLAMF7 also expresses on several hematopoietic lineages including NK cells. Control:Article Title: Efficacy and mechanism of the anti-CD38 monoclonal antibody Daratumumab against primary effusion lymphoma Article Snippet: .. Recombinant Jurkat T cells expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIIa, high affinity (V158) variant and Article Title: Elotuzumab, a potential therapeutic humanized anti-SLAMF7 monoclonal antibody, enhances natural killer cell-mediated killing of primary effusion lymphoma cells Article Snippet: All PEL/MM/mantle cell lymphoma cell lines were grown in RPMI1640 (Fujifilm Wako, Osaka, Japan) supplemented with 10% FBS (Nichirei Bioscience, Tokyo, Japan), 100 IU/ml penicillin and 100 U/ml streptomycin at 37 °C, 5% CO 2 in a humidified atmosphere [ 24 ]. .. Jurkat T cells expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIIa, high affinity (V158) variant and Article Title: Trastuzumab, a monoclonal anti-HER2 antibody modulates cytotoxicity against cholangiocarcinoma via multiple mechanisms. Article Snippet: Cholangiocarcinoma (CCA) is an aggressive and fatal cancer.. The prognosis is very poor and no optimal chemotherapy has been established.. Human epidermal growth factor receptor 2 (HER2, neu, and erbB2) is highly-expressed in breast cancer and is expressed in many other tumors but poorly expressed in CCA. Article Title: Elotuzumab, a potential therapeutic humanized anti-SLAMF7 monoclonal antibody, enhances natural killer cell-mediated killing of primary effusion lymphoma cells. Article Snippet: Primary effusion lymphoma (PEL) is a rare aggressive B-cell non-Hodgkin’s lymphoma with no optimal treatment.. Signaling lymphocytic activation molecule-F7 (SLAMF7, CD319), a type I transmembrane glycoprotein highly expressed in multiple myeloma (MM), represents a promising target for mAb-based immunotherapy.. SLAMF7 also expresses on several hematopoietic lineages including NK cells. Activity Assay:Article Title: Efficacy and mechanism of the anti-CD38 monoclonal antibody Daratumumab against primary effusion lymphoma Article Snippet: .. Recombinant Jurkat T cells expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIIa, high affinity (V158) variant and Article Title: Elotuzumab, a potential therapeutic humanized anti-SLAMF7 monoclonal antibody, enhances natural killer cell-mediated killing of primary effusion lymphoma cells Article Snippet: All PEL/MM/mantle cell lymphoma cell lines were grown in RPMI1640 (Fujifilm Wako, Osaka, Japan) supplemented with 10% FBS (Nichirei Bioscience, Tokyo, Japan), 100 IU/ml penicillin and 100 U/ml streptomycin at 37 °C, 5% CO 2 in a humidified atmosphere [ 24 ]. .. Jurkat T cells expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIIa, high affinity (V158) variant and Article Title: Trastuzumab, a monoclonal anti-HER2 antibody modulates cytotoxicity against cholangiocarcinoma via multiple mechanisms. Article Snippet: Cholangiocarcinoma (CCA) is an aggressive and fatal cancer.. The prognosis is very poor and no optimal chemotherapy has been established.. Human epidermal growth factor receptor 2 (HER2, neu, and erbB2) is highly-expressed in breast cancer and is expressed in many other tumors but poorly expressed in CCA. Article Title: Elotuzumab, a potential therapeutic humanized anti-SLAMF7 monoclonal antibody, enhances natural killer cell-mediated killing of primary effusion lymphoma cells. Article Snippet: Primary effusion lymphoma (PEL) is a rare aggressive B-cell non-Hodgkin’s lymphoma with no optimal treatment.. Signaling lymphocytic activation molecule-F7 (SLAMF7, CD319), a type I transmembrane glycoprotein highly expressed in multiple myeloma (MM), represents a promising target for mAb-based immunotherapy.. SLAMF7 also expresses on several hematopoietic lineages including NK cells. Reporter Assay:Article Title: Efficacy and mechanism of the anti-CD38 monoclonal antibody Daratumumab against primary effusion lymphoma Article Snippet: .. Recombinant Jurkat T cells expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIIa, high affinity (V158) variant and Article Title: Elotuzumab, a potential therapeutic humanized anti-SLAMF7 monoclonal antibody, enhances natural killer cell-mediated killing of primary effusion lymphoma cells Article Snippet: All PEL/MM/mantle cell lymphoma cell lines were grown in RPMI1640 (Fujifilm Wako, Osaka, Japan) supplemented with 10% FBS (Nichirei Bioscience, Tokyo, Japan), 100 IU/ml penicillin and 100 U/ml streptomycin at 37 °C, 5% CO 2 in a humidified atmosphere [ 24 ]. .. Jurkat T cells expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIIa, high affinity (V158) variant and Article Title: Trastuzumab, a monoclonal anti-HER2 antibody modulates cytotoxicity against cholangiocarcinoma via multiple mechanisms. Article Snippet: Cholangiocarcinoma (CCA) is an aggressive and fatal cancer.. The prognosis is very poor and no optimal chemotherapy has been established.. Human epidermal growth factor receptor 2 (HER2, neu, and erbB2) is highly-expressed in breast cancer and is expressed in many other tumors but poorly expressed in CCA. Article Title: Elotuzumab, a potential therapeutic humanized anti-SLAMF7 monoclonal antibody, enhances natural killer cell-mediated killing of primary effusion lymphoma cells. Article Snippet: Primary effusion lymphoma (PEL) is a rare aggressive B-cell non-Hodgkin’s lymphoma with no optimal treatment.. Signaling lymphocytic activation molecule-F7 (SLAMF7, CD319), a type I transmembrane glycoprotein highly expressed in multiple myeloma (MM), represents a promising target for mAb-based immunotherapy.. SLAMF7 also expresses on several hematopoietic lineages including NK cells. |