whsc1 941 1240 (BPS Bioscience)
BPS Bioscience is a verified supplier 
BPS Bioscience manufactures this product 
93
Structured Review
BPS Bioscience
whsc1 941 1240
a ." width="250" height="auto" />
Whsc1 941 1240, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 93/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/51026/pmc05942779-77-1-15?v=BPS+Bioscience
Average 93 stars, based on 2 article reviews
a ." width="250" height="auto" />Whsc1 941 1240, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 93/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/51026/pmc05942779-77-1-15?v=BPS+Bioscience
Average 93 stars, based on 2 article reviews
whsc1 941 1240 - by Bioz Stars,
2026-08
93/100 stars
Images
1) Product Images from "Identification of a peptide inhibitor for the histone methyltransferase WHSC1"
Article Title: Identification of a peptide inhibitor for the histone methyltransferase WHSC1
Journal: PLoS ONE
doi: 10.1371/journal.pone.0197082
a ." title="Biochemical and biophysical peptide inhibitor potency values for WHSC1 941–1240 and WHSC1L1 1054–1285 Figure Legend Snippet: Biochemical and biophysical peptide inhibitor potency values for WHSC1 941–1240 and WHSC1L1 1054–1285
Techniques Used: Sequencing
Figure Legend Snippet: Representative peptide inhibitor biochemical dose-response curves for (A) WHSC1 941–1240 and (B) WHSC1L1 1054–1285. Error bars represent the standard deviation of three independent replicates. Resulting IC 50 values are reported in .
Techniques Used: Standard Deviation
a ." title="Biochemical IC50 values for norleucine peptide inhibitors derived from the H4K44 and H3K36 ... " property="contentUrl" width="100%" height="100%"/>
Figure Legend Snippet: Biochemical IC 50 values for norleucine peptide inhibitors derived from the H4K44 and H3K36 sequences
Techniques Used: Derivative Assay, Sequencing
Figure Legend Snippet: PTD2 biochemical IC 50 values for a panel of HMT enzymes.
Techniques Used:
Figure Legend Snippet: WHSC1 was immobilized on a streptavidin-coated chip and peptide inhibitor was co-injected with SAM utilizing a 3-fold, 5-point dilution series ending at a 20 μM top concentration. Data reported in is presented as the standard deviation of three independent experiments.
Techniques Used: Injection, Concentration Assay, Standard Deviation
Figure Legend Snippet: Upper panel, calorimetric trace for ligand titration; lower panel, binding isotherm from calorimetric trace. WHSC1 concentration in the cell was 10 μM supplemented with 100 μM SAM. PTD2 concentration in the syringe was 100 μM.
Techniques Used: Titration, Binding Assay, Concentration Assay
Figure Legend Snippet: WHSC1 was immobilized on a streptavidin-coated chip and peptide inhibitor was either injected in the absence of cofactor (left panel), co-injected with SAH (middle panel), or co-injected with SFG (right panel) utilizing a 2-fold, 10-point dilution series ending at a 100 μM top concentration.
Techniques Used: Injection, Concentration Assay
Figure Legend Snippet: (A) Superposition of NSD family proteins (green/yellow = WHSC1L1-PTD2 (PDB code = 6CEN); cyan = WHSC1L1 (PDB code = 5UPD); magenta = WHSC1 (PDB code = 5LSU); purple = NSD1 (PDB code = 3OOI). All protein chains are shown as ribbons; SAM and PTD2 are depicted in stick representation. (B) Structure of WHSC1L1-PTD2-SAM ternary complex. Hydrogen bonds are indicated with dashed lines. (C) Superposition of WHSC1L1-PTD2 and SETD2-H3.3 K36M (grey; PDB code = 5JJY).
Techniques Used:
![Fig. 3. Fruiting bodies of Angiococcus disciformis DSM 52716T (a), Cystobacter minus DSM 14751 [b, c, d (side view)] and Cystobacter violaceus DSM 14727T (e). Bars, 100 mm (a, c), 200 mm (b, d, e).](https://pub-med-unpaywalled-images-cdn.bioz.com/pub_med_ids_ending_with_6530/pm26286530/pm26286530__page6_image1.jpg)