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cdk2 cyclin a  (Carna Inc)


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Bioz Manufacturer Symbol Carna Inc manufactures this product  
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    Structured Review

    Carna Inc cdk2 cyclin a
    Cdk2 Cyclin A, supplied by Carna Inc, used in various techniques. Bioz Stars score: 96/100, based on 27 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/04-165/CDK2-CycE1/pm22466726-22-0-5
    Average 96 stars, based on 27 article reviews
    cdk2 cyclin a - by Bioz Stars, 2026-09
    96/100 stars

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    Related Articles

    Recombinant:

    Article Title: Design, Synthesis, and Biological Evaluation of a Series of Spiro Analogues as Novel HPK1 Inhibitors
    Article Snippet: .. The recombinant human CDK2/CycE1 protein (final concentration 1 nM, purchased from Carna Biosciences, Cat No, 04-165) was preincubated with serially diluted ISM compounds (10000-0.50805 nM, 3-fold increments) in a reaction buffer [50mM HEPEs, pH 7.5; 10mM MgCl2; 2mM DTT; 0.01% Triton X100; 0.01% BSA] for 10 min at room temperature. ..

    Article Title: Discovery of Pyridine-2-Carboxamides Derivatives as Potent and Selective HPK1 Inhibitors for the Treatment of Cancer
    Article Snippet: .. The recombinant human CDK2/CycE1 protein (final concentration 1nM, purchased from Carna Biosciences, Cat No, 04-165) was preincubated with serially diluted compounds (10000-0.50805 nM, 3-fold increments) in a reaction buffer [50 mM HEPES, pH 7.5; 10 mM MgCl2; 2 mM DTT; 0.01% Triton X-100; 0.01% BSA] for 10 min at room temperature. ..

    Concentration Assay:

    Article Title: Design, Synthesis, and Biological Evaluation of a Series of Spiro Analogues as Novel HPK1 Inhibitors
    Article Snippet: .. The recombinant human CDK2/CycE1 protein (final concentration 1 nM, purchased from Carna Biosciences, Cat No, 04-165) was preincubated with serially diluted ISM compounds (10000-0.50805 nM, 3-fold increments) in a reaction buffer [50mM HEPEs, pH 7.5; 10mM MgCl2; 2mM DTT; 0.01% Triton X100; 0.01% BSA] for 10 min at room temperature. ..

    Article Title: Discovery of Pyridine-2-Carboxamides Derivatives as Potent and Selective HPK1 Inhibitors for the Treatment of Cancer
    Article Snippet: .. The recombinant human CDK2/CycE1 protein (final concentration 1nM, purchased from Carna Biosciences, Cat No, 04-165) was preincubated with serially diluted compounds (10000-0.50805 nM, 3-fold increments) in a reaction buffer [50 mM HEPES, pH 7.5; 10 mM MgCl2; 2 mM DTT; 0.01% Triton X-100; 0.01% BSA] for 10 min at room temperature. ..

    Labeling:

    Article Title: Substituted pyrimidines as CDK4/6 inhibitors
    Article Snippet: .. CDK2 protein (2.19 nM, CARNA BIOSCIENCE, cat #04-103), florescent labeled substrate FLPeptide18 (2 μM, PerkinElmer, cat #760362) was prepared in kinase assay buffer (100 mM HEPES (pH 7.5), 10 mM MgCl2, 0.05% Brij-35, 0.5 mM DTT and 0.1 mg/ml BSA). ..

    Kinase Assay:

    Article Title: Substituted pyrimidines as CDK4/6 inhibitors
    Article Snippet: .. CDK2 protein (2.19 nM, CARNA BIOSCIENCE, cat #04-103), florescent labeled substrate FLPeptide18 (2 μM, PerkinElmer, cat #760362) was prepared in kinase assay buffer (100 mM HEPES (pH 7.5), 10 mM MgCl2, 0.05% Brij-35, 0.5 mM DTT and 0.1 mg/ml BSA). ..



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