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2 chlorotrityl resin  (Chem Impex International)


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    Structured Review

    Chem Impex International 2 chlorotrityl resin
    2 Chlorotrityl Resin, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/03458/S-Trityl-L-cysteine-2-chlorotrityl+resin/ppr0282645-178-12-14
    Average 95 stars, based on 10 article reviews
    2 chlorotrityl resin - by Bioz Stars, 2026-09
    95/100 stars

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    Related Articles

    Synthesized:

    Article Title: Wollamide Cyclic Hexapeptides Synergize with Established and New Tuberculosis Antibiotics in Targeting Mycobacterium tuberculosis
    Article Snippet: .. Briefly, peptides were synthesized on 2-chlorotrityl resin (0.8 mmol/g; Chem Impex) at a 75-μM scale on a Symphony multiplex synthesizer. ..

    Article Title: Induction of antigen-specific tolerance by nanobody-antigen adducts that target class-II major histocompatibility complexes.
    Article Snippet: 1Society of Fellows, Harvard University, Cambridge, MA, USA.. 2Program in Cellular and Molecular Medicine, Boston Children’s Hospital, Boston, MA, USA.. 3Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.

    Article Title: Wollamide Cyclic Hexapeptides Synergize with Established and New Tuberculosis Antibiotics in Targeting Mycobacterium tuberculosis.
    Article Snippet: .. Briefly, peptides were synthesized on 2-chlorotrityl resin (0.8 mmol/g; Chem Impex) at a 75-mM scale on a Symphony multiplex synthesizer. ..

    Article Title: Targeted delivery of an anti-inflammatory corticosteroid to Ly6C/G-positive cells abates severity of influenza A symptoms
    Article Snippet: .. Peptides were synthesized on 2-chlorotrityl resin (ChemImpex) following standard solid-phase peptide synthesis protocols or were obtained commercially from GenScript. ..

    Article Title: Plasma metal concentrations and their interactions with genetic susceptibility on homocysteine levels.
    Article Snippet: The distribution of Ly6C/G-positive cells in response to an infection of the mouse respiratory tract with influenza A virus was followed noninvasively over time by immuno-positron emission tomography.. We converted nanobodies that recognize Ly6C and Ly6G, markers of neutrophils and other myeloid cells, as well as an influenza hemagglutinin–specific nanobody, into Zr-labeled PEGylated positron emission tomography (PET) imaging agents.. The PET images showed strong accumulation of these imaging agents in the lungs of infected mice.

    Multiplex Assay:

    Article Title: Wollamide Cyclic Hexapeptides Synergize with Established and New Tuberculosis Antibiotics in Targeting Mycobacterium tuberculosis
    Article Snippet: .. Briefly, peptides were synthesized on 2-chlorotrityl resin (0.8 mmol/g; Chem Impex) at a 75-μM scale on a Symphony multiplex synthesizer. ..

    Article Title: Wollamide Cyclic Hexapeptides Synergize with Established and New Tuberculosis Antibiotics in Targeting Mycobacterium tuberculosis.
    Article Snippet: .. Briefly, peptides were synthesized on 2-chlorotrityl resin (0.8 mmol/g; Chem Impex) at a 75-mM scale on a Symphony multiplex synthesizer. ..

    Blocking Assay:

    Article Title: Oleyl Conjugated Histidine-Arginine Cell-Penetrating Peptides as Promising Agents for siRNA Delivery
    Article Snippet: .. The protected building block amino acids (arginine and histidine) and arginine preloaded on 2-chlorotrityl resin were purchased from Chem Impex Inc. (Bensenville, IL, USA). .. 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate (HBTU) was purchased from Acrotein ChemBio Inc. (Hoover, AL, USA).

    other:

    Article Title: Se-Glargine I. Chemical Synthesis of a Basal Insulin Analog Stabilized by an Internal Diselenide Bridge
    Article Snippet: 2-Chlorotrityl-resin (loading of 0.3-0.8 eq/g) was purchased from Chem-Impex International.



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    Podocyte-specific TLR4 deletion mitigated STZ-induced DKD, podocyte injury, and proteinuria in mice. (A) Schematic description of the strategy for generating STZ-induced diabetic mouse model in NPHS2 -Cre; TLR4 fl/fl ( TLR4 CKO) mice and in TLR4 fl/fl mice (CTL). (B) Monthly monitoring of plasma glucose levels in mice. Data are presented as mean ± SD. ** P < 0.01 vs. CTL-NC; ## P < 0.01 vs. CKO-NC. (C) Monthly monitoring of body weight in mice. Data are presented as mean ± SD. ** P < 0.01 vs. CTL-NC; # P < 0.05 vs. CKO-NC; # # P < 0.01 vs. CKO-NC; # ### P < 0.01 vs. CTL-STZ. (D) Representative images of PAS and MASSON staining of the glomeruli in mice at 12 and 16 weeks. Scale bar, 20 μm ( n = 8). (E) Representative images of HE staining of the kidney in mice at 12 and 16 weeks. Scale bar, 50 μm ( n = 8). (F) Representative IF images of the expression of SD proteins p-cadherin and synaptopodin in glomeruli at 12 and 16 weeks. Scale bar, 20 μm ( n = 8). (G) The expression of a mesenchymal marker desmin was detected in renal tissues from mice at 12 and 16 weeks by western blot analysis. P values were determined by one-way ANOVA and data are presented as mean ± SD. **** P < 0.01; # P < 0.05; ## P < 0.05 ( n = 8). (H) Representative images of TEM in podocyte ultrastructural alterations in mice. FPs effacement (blue arrow), ER dilation (red arrow) and GBM thickness were observed in podocytes in STZ-induced CTL diabetic mice, and were attenuated in TLR4 CKO diabetic mice at 16 weeks. Scale bar, 1 μm ( n = 8). (I) Determination of proteinuria in mice. Data are presented as mean ± SD. ** P < 0.01 vs. CTL-NC; # P < 0.05 vs. CKO-NC; # # P < 0.01 vs. CKO-NC; # ## P < 0.05 vs. CTL-STZ; # ### P < 0.01 vs. CTL-STZ.

    Journal: Journal of Advanced Research

    Article Title: Podocyte TLR4 deletion alleviates diabetic kidney disease through prohibiting PKCδ/SHP-1-dependent ER stress and relieving podocyte damage and inflammation

    doi: 10.1016/j.jare.2025.07.013

    Figure Lengend Snippet: Podocyte-specific TLR4 deletion mitigated STZ-induced DKD, podocyte injury, and proteinuria in mice. (A) Schematic description of the strategy for generating STZ-induced diabetic mouse model in NPHS2 -Cre; TLR4 fl/fl ( TLR4 CKO) mice and in TLR4 fl/fl mice (CTL). (B) Monthly monitoring of plasma glucose levels in mice. Data are presented as mean ± SD. ** P < 0.01 vs. CTL-NC; ## P < 0.01 vs. CKO-NC. (C) Monthly monitoring of body weight in mice. Data are presented as mean ± SD. ** P < 0.01 vs. CTL-NC; # P < 0.05 vs. CKO-NC; # # P < 0.01 vs. CKO-NC; # ### P < 0.01 vs. CTL-STZ. (D) Representative images of PAS and MASSON staining of the glomeruli in mice at 12 and 16 weeks. Scale bar, 20 μm ( n = 8). (E) Representative images of HE staining of the kidney in mice at 12 and 16 weeks. Scale bar, 50 μm ( n = 8). (F) Representative IF images of the expression of SD proteins p-cadherin and synaptopodin in glomeruli at 12 and 16 weeks. Scale bar, 20 μm ( n = 8). (G) The expression of a mesenchymal marker desmin was detected in renal tissues from mice at 12 and 16 weeks by western blot analysis. P values were determined by one-way ANOVA and data are presented as mean ± SD. **** P < 0.01; # P < 0.05; ## P < 0.05 ( n = 8). (H) Representative images of TEM in podocyte ultrastructural alterations in mice. FPs effacement (blue arrow), ER dilation (red arrow) and GBM thickness were observed in podocytes in STZ-induced CTL diabetic mice, and were attenuated in TLR4 CKO diabetic mice at 16 weeks. Scale bar, 1 μm ( n = 8). (I) Determination of proteinuria in mice. Data are presented as mean ± SD. ** P < 0.01 vs. CTL-NC; # P < 0.05 vs. CKO-NC; # # P < 0.01 vs. CKO-NC; # ## P < 0.05 vs. CTL-STZ; # ### P < 0.01 vs. CTL-STZ.

    Article Snippet: NPHS2 -Cre mice and TLR4 floxed mice (C57BL/6n background) were purchased from Cyagen Biosciences (Guangzhou, China).

    Techniques: Clinical Proteomics, Staining, Expressing, Marker, Western Blot