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aminocyanophthalide 6  (Chem Impex International)


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    Structured Review

    Chem Impex International aminocyanophthalide 6
    Aminocyanophthalide 6, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/02323/2-Hydroxypyridine/us08709431-539-29-3
    Average 95 stars, based on 1 article reviews
    aminocyanophthalide 6 - by Bioz Stars, 2026-09
    95/100 stars

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    Article Title: Enediyne compounds, conjugates thereof, and uses and methods therefor
    Article Snippet: Boc-protected citrulline 6a (Chem-Impex, 0.726 g, 2.64 mmol) and N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC, 0.578 g, 2.9 mmol) in DCM:DMF (17:3, 20 mL) was stirred at RT for 30 min. Then aminocyanophthalide 6 (0.23 g, 1.32 mmol) was added and stirred at RT for 18 h. The reaction mixture was worked up with ethyl acetate, washed with saturated NaHCO3 solution, and further washed with water and brine.

    Article Title: Enediyne compounds, conjugates thereof, and uses and methods therefor
    Article Snippet: Boc-protected citrulline 6a (Chem-Impex, 0.726 g, 2.64 mmol) and N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC, 0.578 g, 2.9 mmol) in DCM:DMF (17:3,20 mL) was stirred at RT for 30 min. Then aminocyanophthalide 6 (0.23 g, 1.32 mmol) was added and stirred at RT for 18 h. The reaction mixture was worked up with ethyl acetate, washed with saturated NaHCO3 solution, and further washed with water and brine.

    Article Title: Supramolecular Click Product Interactions Induce Dynamic Stiffening of Extracellular Matrix-Mimetic Hydrogels.
    Article Snippet: Progressive stiffening of the extracellular matrix (ECM) is observed in tissue development as well as in pathologies such as cancer, cardiovascular disease, and fibrotic disease.. However, methods to recapitulate this phenomenon in vitro face critical limitations.. Here, we present a poly(ethylene glycol)-based peptide-functionalized ECM-mimetic hydrogel platform capable of facile, user-controlled dynamic stiffening.



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