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pybrop  (Chem Impex International)


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    Structured Review

    Chem Impex International pybrop
    Pybrop, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/02275/Bromo-tris-pyrrolidino-phosphonium+hexafluorophosphate/pm37071494__jo3c00145_si_001-15-5-9
    Average 95 stars, based on 5 article reviews
    pybrop - by Bioz Stars, 2026-09
    95/100 stars

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    Related Articles

    other:

    Article Title: Oxime-based linker libraries as a general approach for the rapid generation and screening of multidentate inhibitors
    Article Snippet: Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate, PyBroP (Chem-Impex, cat. no. 02275).

    Article Title: Rapid esterification of nucleosides to solid-phase supports for oligonucleotide synthesis using uronium and phosphonium coupling reagents.
    Article Snippet: Nucleosides can be esterified to solid-phase supports using uronium or phosphonium coupling reagents and a coupling additive, such as 1-hydroxybenzotriazole (HOBT), 7-aza-1-hydroxybenzotriazole (HOAT), N-methylimidazole (NMI), or 4-(dimethylamino)pyridine (DMAP).. However, DMAP was far superior to other additives and high nucleoside loadings (up to 60 μmol/g) and rapid coupling reactions (e10 min) were possible.. Hydroxyl-derivatized CPG was attached to nucleosides with 3′-succinyl or 3′hydroquinone-O,O′-diacetic acid (HQDA or Q-Linker) carboxyl groups through a primary ester linkage.

    Article Title: Pyrazoles
    Article Snippet: Method C Preparation of Compounds of the Invention According to Method C A mixture of the amine (0.2 mmol), 1-methyl-5-phenyl-1H-pyrazole-4-carboxylic acid (40 mg, 0.2 mmol, Maybridge plc, Cornwall, UK), DIPEA (0.14 mL, 0.8 mmol, Aldrich), PyBrop (Chem-Impex International, Inc., Wood Dale, Ill.; 102 mg, 0.8 mmol) and DMAP (0.5 mg, 0.004 mmol, Aldrich) in dry dichloromethane (2 mL) was stirred overnight at room temperature.

    Article Title: Pyrazoles
    Article Snippet: 5-Bromo-1-methyl-1H-pyrazole-4-carboxylic acid (29.6 mmol), decahydro-quinoline (Aldrich Chemical Company, Inc., Milwaukee, Wis.; 4.9 g, 35.5 mmol), diisopropylethylamine (11 mL, 59.2 mmol), and PyBrop (bromo-tris-pyrrolidino-phophonium hexafluorophosphate) (Chem-Impex International, Inc., Wood Dale, Ill.; 16.6 g, 35.5 mmol) were mixed together in dry dichloromethane (70 mL) and dry dimethylformamide (20 mL).

    Purification:

    Article Title: Preparation of Heteroaryl Ethers from Azine N-Oxides and Alcohols.
    Article Snippet: .. For the experiments described herein, PyBroP was purchased from Chem-Impex International, Inc., and used without further purification. ..

    Transferring:

    Article Title: Oxime-based linker libraries as a general approach for the rapid generation and screening of multidentate inhibitors
    Article Snippet: .. 8| Use the multichannel pipette to add 5 μl from the first Titertube row of the diluted inhibitor to the first four rows of the 96-well plate (A1–D12 for screen 1). (continued) © 20 12 N at u re A m er ic a, In c. A ll ri g h ts r es er ve d . 692 | VOL.7 NO.4 | 2012 | nature protocols 1-Hydroxybenzotriazole (HOBT; Aldrich, cat. no. 711489) N,N′-Diisopropylcarbodiimide (DIC; Aldrich, cat. no. D125407) Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate (PyBroP; Chem-Impex, cat. no. 02275) N,N-Diethylisopropylsilane (Aldrich, cat. no. 550043) ! cautIon It is corrosive. .. Piperidine (Aldrich, cat. no. 104094) ! cautIon It is corrosive and toxic.



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