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1 5 hexadiyne  (Thermo Fisher)


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    Structured Review

    Thermo Fisher 1 5 hexadiyne
    1 5 Hexadiyne, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/018720%2E04/1%2C5-Hexadiyne%2C+50%25+in+pentane/pm36617235-44-4-11
    Average 94 stars, based on 1 article reviews
    1 5 hexadiyne - by Bioz Stars, 2026-09
    94/100 stars

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    other:

    Article Title: Aerobic catabolism of isobutylene by Mycolicibacterium sp. ELW1 requires inducible, plasmid-borne ibc genes
    Article Snippet: The organic chemicals used in this study, their purities, and the suppliers are as follows: Alexa Fluor 647 azide, triethylammonium salt (99% purity; Invitrogen, Grand Island, NY, USA); Tris-hydroxypropyltriazolylmethylamine (95% purity; Lumiprobe, Hunt Valley, MD, USA); 1,5-hexadiyne (50% [vol/vol] in pentane; Alfa Aesar, Ward Hill, MA, USA); 2-methyl-1,2-epoxypropane (isobutylene oxide, 99+%; Alfa Aesar, Ward Hill, MA, USA); 2-methyl-1,2-propanediol (Oakwood Chemical, Estill, SC, USA); PageRuler Prestained NIR Protein Ladder (Thermo Scientific, Waltham, MA, USA).

    Article Title: Diyne inactivators and activity-based fluorescent labeling of phenol hydroxylase in Pseudomonas sp. CF600.
    Article Snippet: An activity-based labeling (ABL) approach was investigated for the phenol-oxidizing bacterium, Pseudomonas sp. CF600.. Phenol-grown cells were exposed to several different terminal diynes, and following cell breakage, extracts of these cells were added to coppercatalyzed alkyne/azide cycloaddition reactions containing Alexa Fluor 647 azide.. Analysis of total cell proteins by sodium dodecyl sulfate–polyacrylamide gel electrophoresis and near-infrared scanning demonstrated covalent fluorescent labeling of a 58and a 34kDa polypeptide in all diyne-treated cell types.

    Article Title: Activity-Based Protein Profiling of Ammonia Monooxygenase in Nitrosomonas europaea
    Article Snippet: 1,5-Hexadiyne (50% v/v in pentane) was obtained from Alfa Aesar (Ward 168 Hill, MA).

    Article Title: Total Synthesis and Biological Evaluation of (5Z,9Z)-5,9-Hexadecadienoic Acid, an Inhibitor of Human Topoisomerase I
    Article Snippet: The naturally occurring (5Z,9Z)-5,9-hexadecadienoic acid was synthesized stereochemically pure in six steps starting with commercially available 1,5-hexadiyne.. The title compound was antimicrobial against the Gram-positive bacteria Staphylococcus aureus (MIC 80 μM) and Streptococcus faecalis (MIC 200 μM), but inactive against Gram-negative bacteria such as Pseudomonas aeruginosa.. In addition, the (5Z,9Z)5,9-hexadecadienoic acid completely inhibits human topoisomerase I at a concentration of 800 μM, while 5,9-hexadecadiynoic acid and hexadecanoic acid do not inhibit topoisomerase I (>1000 μM).

    Purification:

    Article Title: Silver(I) Double and Multiple Salts Containing 1,5-Hexadiyne-1,6-diide and Nitrate Ions
    Article Snippet: Five new silver(I) double and triple salts containing conformationally flexible 1,5-hexadiyne-1,6-diide (−C CCH2CH2C C , C6H4) and nitrate ions, namely Ag2C6H4 ·7AgNO3 (1) , Ag2C6H4 ·3AgNO3 ·2AgF (2) , A g 2 C 6 H 4 · 4 A g NO 3 · 2 L 1 ( 3 ; L 1 = i m i d a z o l e ) , Ag2C6H4 ·2AgNO3 ·2AgL2 (4 ; HL2 = pyrazole), and Ag2C6H4·4AgNO3·2L3 (5; L3 = 3,5-dimethylpyrazole), have been synthesized, in which the C6H4 2− species was found to adopt two distinct configurations: anti in 1 and 3 and gauche in 2, 4, and 5.. Complex 1 features an unusual Ag5⊂C6H4⊃Ag4 aggregate as the basic building unit, and such aggregates are interconnected by the nitrate ions to generate a three-dimensional coordination network.. Complex 2 exhibits a three-dimensional coordination network constructed with compact C6H4⊃Ag7 units, nitrate ions, and fluoride ions that assume a μ3 trigonal-pyramidal coordination mode.



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